n
Epithelial hyperplasia
Atypical ductal hyperplasia
Intraductal papilloma
Intraductal carcinoma
Ja
wn
Duct ectasia with inflammatory change fe)
ae 5 DCIS
Ductal epithelial hyperplasia id, a
Infiltrating ductal carcinoma ID:
Fibrocystic change is 5
Mucinous carcinoma
Papilloma
ADH (atypical ductal hyperplasia)
Sclerosing adenosis
location
Border
length
Morphology
margin
Micro calcification
Surrounding
hypoechogenicity
ductal wall
contents
DUPLEX
Mostly central
Clear
Less than 1 cm
Regular
Well defined
Absent
If present in periductal mastitis
thin
Inspissated secretion ,clotted
blood
No flow or minimal periductal
Mostly peripheral
Unclear
Larger than 1 cm
Irregular
Ill defined
Present
present
thickening
Mass attached to wall .no move
in changing position
Flow in mass
The differential diagnosis for an intraductal mass
inspissated secretions
Infection
Hemorrhage
solitary or multiple papillomas
malignancy (DCIS IDC)
most disease arising in the TDLU
ÁMDS3 pauwyy JG
AMDSZ peuuuy J
Untreated duct ectasia —— > obliteration of the
breast ducts ———» abscess formation.
ducts dilate ——> contain cholesterol crystals,
calcification, and protein ———» _ inflammatory
reaction ——> nipple discharge.
Dr Esawy
Dr Anmed Esawy
Dr Esawy
Ja
sy
Benign ductal Diseases
ÁMDS3 pauwyy JG
‘ductal ectasia with debris on it
freely movable Not attaches to wall , diffuse
ÁmDs3 pauyyv JG
Dilated ducts secondary to benign duct ectasid ina patient with pain behind the nipple and
in the retroareolar region. US images of the left breast, obtained at the 3-0'clock position, show tubular
anechoic areas (arrowheads) behind the nipple (a) and in the retroareolar region (b). N in b = nipple
well defined duct ectasia with intraductal homogeneous echogenecity (arrows) in the subareolar
area of the left breast.
An echogenic intraductal nodule (arrowhead) is shown
no evidence of intraductal calcification
benign duct ectasia
CC Mammogram show radiodense tubular structures
(arrow) converging toward the nipple in the anterior
and slightly superior right breast
Amps3 pPaWUY Jd
jal MRI of breasts shows hyperintense
tine ectatic ducts
Bilateral Severe
Mammary Duct
Ectasia
multiple dilated branching ducts. no
associated microcalcifications
US image shows anechoic tubular structures extending
toward the nipple, findings that correspond to dilated
ectatic ducts. Note the focal areas of dilatation (arrows)
Duct ectasia. (a, b) vo (a)
and spot compression MLOXb)
mammograms show radio: se
tubular structures convergit
toward the nipple in the anterior
and slightly superior right bri
(arrows in b).
—
GE à E. À
tissue surrounding the dilated
which contain echogenic debris ducts is hypervascular
Duct ectasia with inflammatory infiltrates in woman. MLO (a) and craniocaudal (b)
DE with Inflammatory Infiltrates
ÁmDs3 pauyyv JG
DE with Inflammatory Infiltrates
magnified craniocaudal mammogram (e) show
focal ductal dilatation with well-circumscribed
tubular encapsulated-appearing masses (arrow in ¢)
in the upper outer quadrant of the right breast
a -
focal ductal dilatation, There are soft-tissue nodules no associated flow within the masses
(arrows in d) within the duct, which correspond to
the masses seen at mammography.
Amps3
DE with Inflammatory Infiltrates
palpable or nonpalpable suspected ductal processer
lesion =
US evaluation is critical for correct diagnosis of
inflammatory infiltrates
ÁMDS3 PSWUY
Percutaneous biopsy is often required to exclude a
malignant cause
tetroareolar region show a 7-mm cyst with multiple tiny septa
dilated ducts and adjacent cysts that may contain inspissated secretions
Apocrine metaplasia in a woman with a history of bilateral milky nipple
discharge and subsequent bloody nipple discharge from a duct
Papillomas
Typically, they are located within a few centimeters of the
nipple and grow within the duct
asymptomatic or manifest as serous or sanguineous nipple
discharge
increased upgrade
potential include lesion size greater than 1 cm
lesion location more than 3 cm from the nipple
patient age greater than 50 years
Most institutions warrant surgical excision for CNB papilloma
ÁMDS3 pauwyy JG
RL
>
Papilloma in a woman with spontaneous nipple discharge
retroareolar region at the 12-0'clock position show dilated ducts
and a solid intraductal mass (arrow)
Pathologic intraductal papilloma
+ MAMMOGRAMot least three no
rows) in the pe ”
anterior and posterior LEFT bi y yu
e
#4 DA Papillomatosis
a
Papilloma. Mammography shows a round, hyper dense
lesion with not well demarcated margins that is located
more than 3cm from the nipple
ÁmDs3 pauyyv JG
Mammographic s fatt surrounding
benign lesions that displace fat by their mass effect
rather than invading surrounding fatty tissue
(arrowheads) — pe:
tubular structure/asymmetric ductal d
nonsubareolar location (arrows) Im
a
E a mo
anechoic dilated Socle regul
contours that measure 2 cm (cal )
— - -
multiple papillomas tend to occur in distal ducts in the TOL
>
They are more often associated with =
Hyperplasia 2
Atypia m
DEIS ro}
invasive cancer 3
sclerosing adenosis
radial scars
Malignant ductal Diseases
ÁMDS3 pauwyy JG
Dr
sawy
seal
US image shows a dilated duct containing an hypoechoic intraductal mass with arterial flow
ÁmDs3 pauyyv JG
A =
ss comedo type DCIS ne =
ill defined duct ectasia filled with intraductal heterogeneous echogenecities and intraductal
nodules in the peripheral portion
associated ductal wall thickening (arrows).
mucinous carcinoma with infiltrating ductal components
several aggregated cysts with ill-defined duct ectasia are noted in the peripheral ducts
Intraductal heterogeneous hypoechogenicities with ductal wall thickenings (arrows)
Surrounding hypoechoic parenchymal change (arrowheads)
Bilateral mammograms show a 4-
cm segment of asymmetrically
dilated ducts in the upper inner
quadrant of her right breast
(arrows).
overall indistinct structure of the
ductal walls irregular, serpiginous
shape
No suggestive calcifications or
discrete masses
ductal structures inthe right breast
branching, irregular, serpiginous hypoechoic ductal structures with internal
echogenicity that extend toward the upper inner aspect of the breast (arrows)
Typically DCIS manifests as calcifications at mammography
4% of cases it may manifest as a solid mass with or withouß
associated calcifications
ÁMDS3 pa
ESOO po e mass (cursors),
in a dilated duct (arrow). The mass
conteins multiple punctate echogenic
foci, a finding suspicious for
DC IS in woman with
a 2-week history of new-
onset nipple discharge
small focus of pleomorphic
microcalcifications (arrow) in
the retroareolar region
large irregul
mass with
echotextu
nipple
za #4 :
focal asymmetry with associated distortion in the =
central upper right breast, a finding that corresponds pe 4
to the area of concern as indicated by the patient. e
MR imaging with contrast material diagnose
several occult malignancies in the setting of
sanguineous nipple discharge
Although negative imaging work-up for nipple
discharge
ÁMDS3 pauwyy JG
high-nuclear-grade ductal carcinoma in
situ (DCIS) of the solid and pbpillary
types with associated sec
focal necrosis
mi - —
US image shows a dilated duct (arrow)
filled with hypoechoic material
containing a few isoechoic-hyperechoic
foci (arrowhead
Color Doppler image shows periductal hypervascularity
Ultrasound features of mammary duct ectasia. (A) Ultrasound-identified pipe-like hypo
echo under the right nipple (arrow) with clear border. (B) Color Doppler flow imaging identified
weak blood signals. Arrow indicates the thick dotted echo and cloddy hyper echo
IDC not intraductal papilloma.
Invasive ductal carcinoma misdiagnosed as Color Doppler flow imaging identified no
intraductal papilloma using US. (A) Solid blood signal. US diagnosed intraductal
nodules and dilated duct under the right papilloma.
nipple with smooth and clear pipe wall
Intraductal papilloma diagnosed using US with MRI. 2 Series yes echo sel “lies
(A) US identified a hyper echo nodule with dilated uct Under the nipple [arrow] and clear border.
a Color Doppler flow imaging identified no blood
duct above the nipple (arrow). = # = à
signal. US diagnosed intraductal papilloma
normal ducts are not typically visible, they intersperse with the
background breast parenchyma >
ducts are dilated non-enhanced T1-weighted images as ne
signal-intensity branching tubular structures an appearance due
to proteinaceous or sometimes hemorrhagic material in its
interior
Amos
Usually no associated enhancement with contrast medium
Papilloma. MR Sagittal contrast-enhanced fat-
saturated Tl-weighted
enhancing ovoid lesion (arrow) near the nipple