Buffer system for bph

Buffer system for bph

1. BUFFER SYSTEM MAN BAHADUR RANA BPH ACAS,NEPAL

2. A buffer solution  a weak acid mixed with its conjugate base ( or weak base and conjugate acid ) resist changes in pH when a small amount of a strong acid or base is added to it. Definition Buffer solutions

3. Eg : Acetate buffer. Bicarbonate buffer Buffers  constant pH values  the ability to resist changes in pH. They are used to calibrate the pH meter. Buffer solutions

4. Biological Buffer system Buffer solutions

5. A- Bicarbonate buffer system: • plasma (NaHCO3 /H2CO3 ). carbonic acid  proton donor bicarbonate  proton acceptor : Buffer solutions

6. plasma and the intracellular fluids conjugate bases (Pr−) at the blood pH 7.4 and form conjugate acids ( HPr ) accepting H+. The protein buffer system Buffer solutions

7. 1. The Phosphate Buffer System cytoplasm of all cells, Na2HPO4 /NaH2PO4 H2PO4 – acts as proton donor and HPO4 2– as proton acceptor : Buffer solutions

8. buffering CO2 RBC Inside RBC, CO2 + H2O  (H2CO3) carbonic anhydrase . In lungs Hemoglobin buffer system Buffer solutions

9. an acidic (−COOH) and a basic (− NH2) group. zwitterion The aminoacid buffer system Buffer solutions OH-