Calcium metabolism, vitamin d, parathyroid hormone

1. Calcium Metabolism, Vitamin D,
Parathyroid Hormone and Calcitonin
Shibani Hegde-080201024
Riddhi Joshi-080201027

2. Calcium-Importance
•Key role played by calcium in:
1.Skeletal muscle contraction
2.Cardiac muscle contraction
3.Smooth muscles contraction
4.Blood clotting
5.Transmission of nerve impulses

3. Distribution of Calcium in the Body
% distribution of total
body calcium
•1. ECF - 0.1%
•2. Intracellular – 1%
•3. Bones – Rest (Serve
as Reservoirs)
•Calcium Distribution in
ECF

4. Calcium Exchange Between Different
Tissue Compartments
1000

5. Bone And Its Relation to Extracellular
Calcium
•Bone = matrix (collagen + ground substance) +
salts (mostly hydroxyapetite, some
amorphous)
•Exchangeable calcium – readily mobilizable
salts like calcium phosphate and other
amorphous salts

6. Bone And Its Relation to Extracellular
Calcium
•Bone = matrix (collagen + ground substance) +
salts (mostly hydroxyapetite, some
amorphous)
•Exchangeable calcium – readily mobilizable
salts like calcium phosphate and other
amorphous salts