Cerbera thevetia

for under graduates

1. CERBERA thevetia ANAKHA RAJENDRAN ROLL NO:23

2. CERBERA THEVETIA IS A POISONOUS PLANT NATIVE TO CENTRAL AND SOUTHERN MEXICO ALL PARTS OF THE PLANT ARE POISONOUS THE FLOWERS ARE LARGE,BELL SHAPED AND YELLOW,SPIRALLY TWISTED LOBES AND SPREADING LEAVES ARE LANCEOLATE SHAPED FRUIT IS GLOBULAR LIGHT GREEN,CONTAINS A SINGLE NUT WHICH IS TRIANGULAR WITH 4 CHAMBERS EACH ENCLOSING A PALE YELLOW SEED WITH A DEEP GROOVE ALONG THE EDGE SEEDS CONTAIN 4% OF CARDIAC GLYCOSIDE ‘THEVETIN’ MILKY JUICE EXUDES FROM ALL PARTS OF THE PLANT

3. ACTIVE PRINCIPLES THEVETIN THEVETOXIN CERBERIN NERIFOLIN PERUVOSIDE RUVOSIDE

4. SIGNS AND SYMPTOMS SAP OF THE PLANT MAY CAUSE INFLAMMATION IN SENSITIVE INDIVIDUALS CHEWING THE BARK OR SEED KERNEL CAUSES A SLIGHT NUMBING SENSATION AND FEELING OF HEAT IN THE MOUTH AND PURGING INGESTION CAUSES BURNING PAIN IN THE MOUTH,DRYNESS OF THROAT,TINGLING AND NUMBNESS OF TONGUE,VOMITING,DIARRHOEA,HEADACHE GIDDINESS,DILATED PUPILS,LOSS OF MUSCULAR POWER AND FAINTING PULSE IS RAPID,WEAK AND IRREGULAR BLOOD PRESSURE LOW HEART BLOCK,COLLAPSE AND DEATH FROM PERIPHERAL CIRCULATORY FAILURE OCCURS

5. FATAL DOSE 8-10 SEEDS:15-20 g ROOT:5-10 LEAVES FATAL PERIOD 2-3 HOURS

6. POST MORTEM APPEARANCES STOMACH AND DUODENUM MAY BE CONGESTED AND SHOWS FRAGMENTS OF SEEDS

7. TREATMENT WASH OUT THE STOMACH SODIUM MOLAR LACTATE TRANSFUSION WITH GLUCOSE AND 1mg ATROPINE,2ml ADRENALINE AND 2mg NORADRENALINE IS BENEFICIAL ACTIVATED CHARCOAL ANTI ARRHYTHMIC DRUGS ARE INDICATED IN THE PRESENCE OF ARRHYTHMIAS SYMPTOMATIC TREATMENT

8. CIRCUMSTANCES OF POISONING ROOT AND SEEDS ARE USED FOR SUICIDE AND HOMICIDE ROOT AND SEEDS ARE USED FOR CRIMINAL ABORTION CATTLE POISONING:SEEDS ARE CRUSHED AND FED TO THE ANIMAL WITH CORN OR BREAD

9. PRESERVATION OF VISCERA THE USUAL VISCERA TAKEN FOR CHEMICAL ANALYSIS: STOMACH WITH CONTENTS AND 30cm OF UPPER INTESTINE IN ONE BOTTLE 500gm OF LIVER AND HALF OF EACH KIDNEY IN THE SECOND BOTTLE 30ml OF BLOOD 30ml OF URINE A SAMPLE OF THE PRESERVATIVE SHOULD BE TAKEN IN ANOTHER BOTTLE RECTIFIED SPIRIT IS A GOOD PRESERVATIVE IN CASE OF PLANT POISONING SINCE PLANT POISONS ARE GLYCOSIDES AND ALKALOIDS WHICH REACT WITH SODIUM CHLORIDE

10. THANK YOU THANK YOU