About the disease 01 Routes of Infection 02 Pathogenesis and its clinical signs 03 Gross lesions 04 Microscopic lesions 05 Diagnosis 06 Table of contents
About the disease 01 Highly contagious disease of pig characterized by Intestinal disturbances, diarrhea, pneumonia and skin hemorrhages
Swine fever , also known as Hog cholera or Swine plague , is a disease native to America. It is highly contagious and its prevalence led to the first notice of an animal disease by the federal government in 1860 Introduction
Etiology Only one serotype Virus family Flaviviridae Virus genus Pestivirus About the disease
Incubation period : 1 to 4 days by artificial infection and 7 days in natural infection
The virus enters blood Pathogenesis Erythematous patches of skin and enteritis Multiplication in tonsillar tissue 03
Clinical signs Fits Howling
Clinical signs Wobbling gait Coma
04 Gross Lesions 1. Intestine - Necrotic enteritis - Spherical ‘button ulcers’ – Mucosa of Caecum and Colon.
2. Skin - Erythematous patches in the ventral surface of the abdomen and thorax, ears, inner aspects of thigh, perineum and snout
3. Kidney – Subcapsular hemorrhages and renal cortex shows “ Turkey egg ” appearance due to petechiae.
Spleen - Splenic infarcts
5 . Lymph node - Swollen lymph node and red in color.
05 Microscopic lesion Haemorrhages may be seen in the bowman's space and interstitial areas. Button ulcer - Occurs due to infarction, develops following occlusion of small arterioles by swelling and hydropic changes in its endothelium. Splenic infarcts. Disseminated non-purulent meningo-encephalomyelitis. Croupous pneumonia
History Symptoms Lesions Laboratory testing 06 Diagnosis
Laboratory testing: Agar gel precipitation test Fluorescent antibody technique