Classification of antineoplastic agent .pptx

Classification of antineoplastic agent

1. Classification of Antineoplastic Agents Dr. Navidha

2. DRUGS ACTING DIRECTLY ON CELLS (CYTOTOXIC DRUGS) 1.ALKYLATING AGENTS- Nitrogen mustards Mechlorethamine, Cyclophosphamide, Ifosfamide. Ethylenimine Thio-TEPA. Alkyl sulfonate Busulfan. Nitrosourease Carmustin, Lomustine. Triazine Dacarbazine.

3. 2.ANTIMETABOLITES- Folate antagonist Methotrixate. Purine antagonist 6-Mercaopurine, 6-Thioguanine. Pyrimidine 5-Fluorouracil, antagonist Cytarabine . 3.VINCA ALKALOIDS Vincristine , Vinblastine 4.TAXANES Paclitaxal , Docetaxel . 5.EPIPODOPHYLLOTOXIN Etopside .

4. 6.CAMPHOTHECIN Topotecan ANALOOGUES Irinotecan. 7.ANTIBIOTICS ActinomycinD Doxorubicin, Mitoxantrone 8.MISCELLANEOUS Hydrxyurea , Procarbazine , Cisplatin , L- Aasparginase , Carboplatin ,

5. DRUGS ALTERING HORMONAL MILLIEU 1.GLUCOCORTICOIDS Prednisolone 2.ESTROGENS Fosfestrol , Ethylestradiol . 3.SELECTIVE ESTROGEN RECEPTOR MODULATOR Tamoxifen . Toremifene . 4.SELECTIVE ESTROGEN RECEPTOR REGULATOR Fulvestrant 5.AROMATSE Letrozole , INHIBITOR Anastrozole .