Classification of Powders According to Indian Pharmacopoeia_By_Mukesh_Shukla.pptx

Classification of Powders according to Indian Pharmacopoeia

1. Presented by Mr. Mukesh Shukla Assistant professor Hygia institute of pharmacy, Lucknow Classification of Powders According to Indian Pharmacopoeia (IP)

2. Classification of Powders According to Indian Pharmacopoeia Why Classify Powders? Ensures uniformity and quality in pharmaceutical formulations Controls particle size for efficacy, stability, and safety Facilitates proper processing and dosage form design

3. Official Grades of Powder by IP Coarse Powder Moderately Coarse Powder Moderately Fine Powder Fine Powder Very Fine Powder

4. Coarse Powder Passes through sieve No. 10 (aperture 1700 µm) Not more than 40% passes through sieve No. 44 (355 µm) Used for bulk powders where large particle size is acceptable

5. Moderately Coarse Powder Passes through sieve No. 22 (710 µm) Not more than 40% passes through sieve No. 60 (250 µm) Intermediate particle size for moderate dissolution rates

6. Moderately Fine Powder Passes through sieve No. 44 (355 µm) Not more than 40% passes through sieve No. 85 (180 µm) Commonly used for powders requiring finer subdivision

7. Fine Powder Passes through sieve No. 85 (180 µm) No lower limit specified by IP Used when rapid dissolution or absorption is needed

8. Very Fine Powder Passes through sieve No. 120 (125 µm) No lower limit specified by IP Ideal for inhalation powders and topical applications requiring very fine particles

9. Visual Scale Comparison of Powder Grades Coarse powder particles ~ 1700 µm (about the size of a grain of sand) Very fine powder particles ~ 125 µm (about 1/8th the diameter of a human hair) Demonstrates the dramatic size reduction across grades

10. Summary & Importance IP classification standardizes powder quality for pharmaceutical use Particle size impacts drug delivery, stability, and patient safety Understanding these grades helps optimize formulation and manufacturing processes Questions?