cod liver oil

cod liver oil biological source,preparation,chemical cosntiturnts,uses

1. SAM HIGGINBOTTOM UNIVERSITY OF AGRICULTURE TECHNOLOGY AND SCIENCES ALLAHABAD, U.P,211008 Abhishek Kumar Karn B.Pharmacy 3 rd semester Prepared By: Cod liver Oil

2. COD LIVER OIL Synonymes : Oleum morrhi Biological Source : It is prepared from fresh liver of cod fish, Gadus morrhua and other species of Gadus . Family : Gadidae Geographical Source : They are prepared in Scotland, Iceland, Germany, Denmark and Britain. Cod liver oil is a dietary supplement derived from liver of cod fish

3. Preparation: I . Liver are removed from the cod fish. ii . Liver is cleaned thoroughly to make it free from fatty substances and attached tissues like gall-bladder. iii . Then liver are heated in water at about 80°C. iv . The oil exhudes , floats on the top , and separated , washed and water is removed. V . The dehydrated oil is cooled to separate stearin. Vi . The suspended materials are removed by the centrifugation.

4. Description: Colour – Pale yellow thin liquid Taste – Slightly fishy Odour – Fishy It is freely soluble in chloroform, ether, carbon disulphide , and petroleum ether and slightly soluble in alcohol.

5. Chemical constituents: i . It contains of vitamin A and vitamin D. ii. The oil contains glyceryl ester of oleic, linoleic, gadoleic , myristic , Palmitic and other acids. iii. Cod liver oil also contains 7% eicosapaenoic acid and docosahexanoic acid. Chemical Test: I . A solution of cod liver oil in chloroform is treated with sulphuric acid. A violet colour changing to purple or brown is formed due to presence of vitamin A. Ii . Cod liver oil (1ml) dissolved in chloroform (10ml).Few drops of saturated solution of antimony trichloride is added to the solution. A blue coloration is formed due to presence of vitamin A.

6. Uses : 1. The oil is used as source of vitamins. 2. As a nutritive. 3. Treatment of Rickets and Tuberculosis. 4.The application of cod liver oil ointment on wounds to speeds up the healing process. 5.Omega-3 fatty acids in cod liver oil reduces the inflammation of the cells. 6. Cod liver oil cures the gastric ulcers and prevents the development of duodenal ulcers. 7.Reduces cholesterol level. Storage: The oil is sensitive to light and air. It should be stored in air tight , completely filled , coloured containers .

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