compression and compaction.pptx

tablet

1. CONTENTS: PHYSICS OF TABLET COMPRESSION COMPRESSION CONSOLIDATION EFFECT OF FRICTION DISTRIBUTION OF FORCES COMPACTION PROFILE SOLUBILITY

2. COMPRESSION AND COMPACTION COMPRESSION: Compression means reduction of bulk volume of material as a result of the removal of gaseous phase(air) by applied pressure. COMPACTION: Compaction of the powder is the term is used to describe the situation in which the materials are subjected to some level of mechanical force. COMPACTION =Compression + Consolidation of two phases (solid-gas) on application of force.

3. PHYSICS OF TABLET COMPRESSION Tablet compression physics includes: Transmission of forces during compression Distribution of forces in tablets The effect of applied pressure on the relative volume of the powder Interparticulate adhesion and cohesion forces Tablet compression energies Mechanical strength of tablets Detailed description of the tools used in these studies and working methods.

4. STEPS INVOLVED IN THE COMPRESSION OF TABLET: Transitional repacking or particle rearrangement Deformation Fragmentation Bonding (here removal of process) Deformation of solid body Ejection PROCESS OF TABLET COMPRESSION: 1.transitional repacking or particle rearrangement It can be used for stress applied transformation of removal of stress