El (1:100.000)= 0.01 mg = 10 meg
[(1:10.000)= 0.1 mg
3 Use in PEA, Asystole, VF , pulseless VT , anaphylaxis, Asthma, | BP & bradycardia (as
AY block):
> In cardiac arrest (PEA, Asystole, VF, pulseless VT):
v IVILO push: 0.01 mg/kg repeated every 3-5 min (max 1 mg).
Y EDT: mg flow 3 ml NS & 5 breaths (by BWM) (max dose 2.5 mg).
Anaphylaxis (Severe to Moderate):
v IM: 0.01 mg/kg (max 0.3 mg) in upper outer thigh, repeated every 5 - 15 minutes
as needed.
Y IV (Anaphylactic shock): 0.01 mg/kg (1:10,000) over 5 min (max 0.1 mg).
Symptomatic bradycardia/shock; 0.05 — 1 ug/kg/min continuous IV infusion.
Pediat
v
vv
Asthma: 0.01 mg/kg SC q0.5h — q4h x 3 doses, In severe attacks may repeat
q20min x 3 doses (max 0.3 mg).
FIRST DRAWER
A. For ACLS mediations (Recesetation drugs) :
v IV/1O: 1 mg IV push every 3-5 min every 3-5 min (max dose 3 mg).
Y ETT:2-2.5 mg diluted in 5 ml NS flow by 5 breaths (by BVM).
Anaphylaxis (Severe to Moderate):
Y Inhalation Nebulized: 0.5 mL ofdiluted in 2.5 mL normal saline.
æ But the adverse effects, such as tachycardia, arrhythmias, ischemia, and
rebound swelling may limit administration. So ; May repeat once. Do not use
again for at least 3 hrs. Inhalation also given in acute laryngeal edema,
croup, epiglottitis, bronchospasm & asthma.
Y IM: 0.3-0.5 mg (0.3-0.5 mL) in upper outer thigh, repeated every 5-10 min as
necessary.
Y
= Give 1: 10,000 (100 jg) over 5 min every 5-10 min.
= Give 1: 100,000 (10 pg) over 5 min every 5-10 min.
Y Continuous IV infusion (Anaphylactic shock): at rates of 1 - 4 ug/min. why??
may be initiated in adults to prevent the need for repeat epinephrine 1: 10,000
or 1: 100,000,
Symptomatic bradveardia/s hock : 2-10 pg/min continuous IV infusion (tiriate to
response).
3 mg (1:1,000)SC q0.5h- q4h.
FIRST DRAWER
A. For ACLS mediations (Recesetation drugs) :
2) | 1mg/1ml Or 0.5 mg /Iml (0.02 mg/kg)
E, . Use in bradycardia : :
: > Bradycardia with pulse: i
! Pediatric Y IVAO push: 0.02 mg/kg (max dose 0.5 mg) ; May repeat once. :
H Y” ETT: 0.03 mg/kg diluted in 3 ml NS flow by 5 breaths (by BVM). 5
: > Atropine Consider in infant with Succinylcholine. i
Adult > Bradycardia with pulse: E
Y 1% line in AV Block: IV bolus 0.5 mg/kg Repeat every 3 to 5 not
: exceeding the maximum dose of 3 mg.
FIRST DRAWER
A. For ACLS mediations (Recesetation drugs) :
» #
# Use in stabile Narrow PSVT/SVT :
: > IV push fast : 1" dose 0.1 mg/kg IV rapid bolus (max 6 mg), 2" dose 0.2
: Pediatric mg/kg (max 12 mg). (max all dose 18 mg). Following by 10 mL NS.
Adult > IV push fast : 1" dose IV rapid bolus 6 mg, 2™ dose 12 mg rapid bolus, 3"
i dose 12 mg rapid bolus (re peat within 1-2 min). (max all dose 30 mg). :
: Following by 20 mL NS. :
: @® Adenosine used in pregnancy. i
_ Avoid adenosine.| in irregular wide QRS: tachycardia.
A ERA ELPEFFETETETFTETT FE
FIRST DRAWER
A. For ACLS mediations (Recesetation drugs) :
4) 150 mg /3ml > (use in arrhythmias last drugs, For resistant pulseless VT/VF).
# Use in arrhythmias last drugs, For resistant pulseless VT/VE :
> Cardiac Arrest (pulseless VT/VF): 5 mg/kg IV/IO (max 300 mg) bolus
Pediatric diluted with 20 mL dextrose, repeat twice to a max of 15 mg/kg/day.
> Wide complex tachycardia (stable) VT with pulse: 5 mg/kg IV over 20-60
minutes (max 300 mg), may repeat to a max of 15 mg/kg/day.
> Cardiac Arrest (pulseless VT/VF): 300 mg IV/IO bolus diluted in 20 mL
Adult dextrose, repeat 2" dose 150 mg diluted in 20 mL dextrose after 3-5 min,
> Wide complex tachycardia (stable) as VT with pulse: IV over 20-60
minutes, may repeat to a max of 15 mg/kg/day.
2 Don’t use in 2" or 3" degree AV Block.
e,
assis
FIRST DRAWER
A. For ACLS mediations (Recesetation drugs) :
= Use during intubation if patient has increase intracranial pressure (ICP). :
= Lidocaine is recommended when Amiodarone is not available for VT & VF.
> Cardiac Arrest (pulseless VT/VF): 1“ dose 1 mg/kg IV rapid bolus, 2"* dose
Pediatric half 1° dose every 5-10 min. (maximum total dose 3 mg/kg). Following by 5
mL NS (push fast).
æ ETT: 2-3 mg diluted in 5 mi NS flow by 5 breaths (by BVM).
> Wide complex tachyarrhythmia (stable) VI with pulse: 1" dose 1 mg/kg IV
bolus, 2" infusion dose 20— 50 meg/kg/min (maximum total dose 100 mg).
> RSI: 1-2 mg/kg IV push over one min.
Cardiac Arrest (pulseless VT/VF): 1“ dose 1-1.5 mg/kg IV/IO bolus, repeat
2" dose half 1” dose every 5-10 min (maximum total dose 3 mg/kg),
maintain dose 1-4 mg/min (0.014-0.057 mg/kg/min).
> Wide complex tachycardia (stable) as VT: 1* dose 0.5-1.5 mg/kg IVAO
bolus over 2-3 min, 2"* maintain dose infusion dose 20 - 50 mcg/kg/min or
maintain dose 1-4 mg/min (up to 300 mg in any 1-h period).
RSI: 1-2 mg/kg IV push over one
v
Adult
v
FIRST DRAWER
A. For ACLS mediations (Recesetation drugs) :
amide (Sodium channel blocker:
Used with Ventricular Arrhythmia, supraventricular arrhythmias.
= Initial dose: 20-50 mg/min IV, hypotension ensues, or the QRS complex is prolonged by
: 50% from its original duration (maximum dose 17 mg/kg)
: = Maintenance infusion rate: 1-4 mg/min
: = OR100 mg IVevery5 min until the arrhythmia is controlled or one of the above
i conditions is met.
: @ Itshould be avoided in patients with prolonged QT intervals, torsades de pointes, or
A congestive heart failure, atrial fibrillation/flutter, hepatotoxicit:
FIRST DRAWER
A. For ACLS mediations (Recesetation drugs) :
7) METETE sem/t0m
= Used in hypomagnesemia, acute & severe bronchial asthma, severe anaphylactic,
preeclampsia & cardiac arrest only with torsades de pointes or resistant VF (after
ine).
FIRST DRAWER
A. For ACLS mediations (Recesetation drugs) :
Used in hyperkalemia, hypocalcemia, annels blocker overdose or B-adrenergic
blocker overdose, after multiple blood transfusions.
= Routine calcium administration is not recommended during resuscitation because oflack :
of proven efficacy and because of possible harmful effects. :
" Calcium may be given 60 to 100 mg/kg (0.6 to 1.0 mL/kg ofa 10% solution) via the IV.
FIRST DRAWER
A. For ACLS mediations (Recesetation drugs) :
9) ETES as Metoprolol 5 mg , Propranolol 0.1 mg/kg , Esmolol 0.5 mg/kg, Labetalol 100 mg.
Onset | Duration | IV Dose (Adult)
Propranolol | Oral: Oral: Indications: rate control in SVT & VT, AFib/AFlut & HTN.
Vial Smg | 1-2h 6-12h SVT £ VT: 1-3 mg/dose slow IVP; may repeat every 2-5 min
IV: IV: up to a total of 5 mg.
<imin | 4-6h OR 0.5-1 mg over 1 min; may repeat, ifnecessary, up to a
Vial 1g 2-10 ial 250 -500 meg/kg IV over 1 minute; ifnot
min adequate effect followed by maintenance infusion > starting
Pregnancy 50 meg/kg/min IV over 4 min (titrated to therapeutic effect).
category C If not adequate effect response, two additional 150 meg/kg
bolus doses may be given prior to increasing the infusion rate
to 100 meg/kg/min (after second bolus) and 150 meg/kg/min
(after third bolus), as required. After 4 minutes at the rate of
150 meg/kg/min, the infusion rate may be increased to a
maximum rate of 200 meg/kg/min (without an additional
bolus dose).
Metoprolol | Oral: Oral: Indications: HTN, acute MI (oral), angina, rate control in
Smginj |1-2h | 24h AFib/AFlut.
IV: IV: Initial: 1.25-5 mg IV every 5 min up to 15 mg initial dose
Labetalol | Oral: Oral: Indications: HTN.
Vial 100 mg | 20 min- | 8-12h TV bolus (initial): 10 - 20 mg (0,25 mg/kg for an 80-kg) IVP
2h IV: over2 min; may administer 40-80 mg at 10-min intervals
Pregnaney | IV: 2-18h (maximum total cumulative dose 300 mg/kg).
category C | 2-5 min TV infusion (acute loading): Initial: 2 mg/min, titrate to
response (maximum total cumulative dose 300 mg/kg).
à IV Dose :
:| Diltiazem 15-20 mg (0.25 mg/Kg) IV bolus over 2 min, followed by IV infusion at 5-10 mg/h. |:
¿| 20 mg æ Diltiazem used in pregnancy. E
Verapamil | 2.5-5 mg (0.075 to 0.15 mg/Kg) IV bolus over 2-3 min; if after 15 — 30 min the
5 mg dysrhythmia persists, may with a repeat dose 5-10 mg, ifnecessary.
= Verapamil may cause hypotension that can be pre vented by pretreatment
with calcium chloride or gluconate (500 to 1000 mg).
@® Verapamil used in pregnanc
¿o Used for rate control in atrial fibrillation (not first line), atrial flutter, congestive heart failure
: unre lieved by diuretics and ACE inhibitors, paroxsymal atrial tachycardia). :
: = Afib: 0.3 to 0.5 mg jal bolus with a repeat dose in 4 hours. OR
H .25 mg IV every 2 hours up to 1.5 mg total. Repeat dosing is necessary when
H loading digoxin due to the prolonged distribution phase.
> Maintenance dosing is 0.125 to 0.375 mg daily. :
: æ Digoxin contraindicated in patients with ventricular arrhythmias, WPW syndrome (potential :
: for ventricular fibrillation), Acute myocardial infarction, beri-beri heart disease, electrolyte — :
: imbalances, sinus node disease, AV block, and Renal impairment. :
: @ Digoxin used in pregnanc
FIRST DRAWER
A. For ACLS mediations (Recesetation drugs) :
8.4% / 50ml (1 mEq/kg)
Used in prolonged resuscitation with effective ventilation, overdoses ofsodium channel
blocking agents (such as procainamide and tricyclic antidepressants), preexisting
hyperkalemia, not use ful in hypercarbic acidosis such as cardiac arrest and CPR without
intubation, diabetic ketoacidosis.
= Initial dose 1 mEq/kg IV/IO bolus (given only after adequate ventilation with child €
neonates or pre mature infants), then followed by IV/IO infusion of 150 mEq NaHCO 3 /L
: solution to maintain alkalosis — until serum pH > 7.45 (7.50-7.55 for severe overdose).
¿o Without adequate ventilation, the child cannot compensate for the release ofcarbon
i dioxide by buffering the hydrogen ions, and the adverse effects of bicarbonate therapy
surpass any bene ficial effects. the neonates or premature infants, dilute sodium
bicarbonate 1:1 with sterile water, not saline, to reduce the hype rosmolarity of the solution. |
ss AAA
sneeeeeaeeesseneaeed
13) SAR ene 40U IV x 1 > use in pediatric cardiac arrest (Instead of 2" Epi dose)
FIRST DRAWER
B. Sedation and Analgesia drugs:
TABLE Sedative and anesthesia agent, amnesic drugs
Name of drugs TV dose Onset Duration (min)
Morphine 0.1 to 0.2 mg/kg 10 min 240 360
Fentanyl 1 to 2 ng/kg Or 0.05 to 0.4 mg/kg | 1-2 min 30-40
Midozolam 0.1 to 0.2 mg/kg. [1 to 2 min 30-60
Ketamine 500mg/10ml 1 to 4.5 mg/kg. | 2 to 3 min 5 to 10
Etomidate 0.2 to 0.6 mg/kg. [_30 seconds 5 to 10
Propofol 1 to 2.5 mg/kg. | 1 min 5 to 10
C. Muscle relaxant (Paralysis): For rapid sequence intubation (RSD.
FIRST DRAWER
TABLE Skeletal muscle relaxant drugs
Name of drugs IV dose for facilitate intubation. Onset (min) Duration (min)
Succinylcholine 0.5 to 2 mg/kg. (use 2 mg/kg for 1 5-10
Action
a, B, and dopaminergic
+ Dose dependent
= <5 micrograms/kg/min: DA 1,DA 2
5-10 micrograms/kg/min: $ 1
>10 micrograms/kg/min: @
Dobutamine 250mg/5ml inj
2-20 ug/kg/min B, , some f; and a, in large dosages
Norepinephrine 4mg/4ml inj
0.5-50 ug/min Or
0.02-2 ug/kg/min
Primarily a, ‚some ßı
FIRST DRAWER
E. Antidotes drugs
1. Sodium bicarbonate : (see more before).
2. Thiamin: amp.
Thiamin antidote for ethanol toxicity:
* Wernicke’s syndrome (A condition frequently encountered in chronic alcoholics, largely due to
thiamin deficiency and characterized by disturbances in ocular motility, pupillary alterations,
nystagmus, and ataxia with tremors; an organic-toxic psychosis is often an associated finding).
= Korsakoff's syndrome (An alcohol amnestic syndrome characterized by confusion and seve
impairment of memory, especially for recent events, for which the patient compensates by
confabulation; typically encountered in chronic alcoholics; delirium tremens may precede th
syndrome).
— Pediatric Dose: 5-10 mg IV.
— Adult Dose: 100 mg IV.
A. Activated charcoal : 1 gram/kg. Ingestion within the previous hour
Activated charcoal used with all patient ingestion toxic substance within the previous hour by
gastric Lavage via NG tube 36 to 40F-gauge orogastric tube (22 to 24F in children) with Position
the patient on the left side with the head down 20 degrees; toxic substance adsorbed by
activated charcoal; may be effective when given > 60 minutes after ingestion.
Administration: three time gastric Lavage:
1) 1“ time gastric Lavage with 500 mL (10 mL/kg in children) of tap water or Normal saline;
continue until returned fluid is clear.
2) 2" time gastric Lavage with activated charcoal 50 tab via NG tube before removal keep in
10 - 15 minutes then aspiration all fluid with activated charcoal from gastric.
3) 3" time gastric Lavage with activated charcoal 50 tab via NG tube; but keep gastric without
removal.
6.
FIRST DRAWER
E. Antidotes drugs
Antiscropian amp.
CroFab antivenin (ANTISNAKE):
= CroFab antivenin antidote for Rattlesnake bite.
— Five vials minimum dose by infusion in normal saline; increase is rate dependent on
patient’s tolerance; may cause anaphylaxis.
Atropine: Img or 0.5 mg / ml (see more before)
= Atropine antidote for Organophosphates poisoning
— Test dose, 1-2 mg IV in adults, 0.03 mg/kg in children; titrate to drying of pulmonary secretions.
Protopam (PAM): 500 mg /20 ml.
= PAM antidote for Organophos phates poisoning.
— Loading dose: 1-2 g IV in adults, 25-50 mg/kg in children.
— Adult maintenance dose: 500 mg/hr or 1-2 g q4-6h.
Flumaze nil:
= Flumaze nil antidote for Benzodiaze pines.
— Pediatric Dose: 0.01 mg/kg IV.
— Adult Dose: 0.2 mg IV.
10.
FIRST DRAWER
E. Antidotes drugs
Naloxone: 4mg/Iml
= Naloxone antidote for respiratory and neurologic depression due to opioids intoxication
unresponsive to 02 and hyperventilation post RSI or Post-operative such as Morphine, Codeine
& Heroin.
% Examination Findings (most common in bold): Miosis, respiratory de pression, central
nervous system depression, Hypothermia, bradycardia.
— Foradults: Bolus: 0.04 - 2 mg IV/IO/IM/SC/IN every 2 minutes to effect. IV Infusion: 2/3
effective bolus dose.
— For pediatric: Bolus: 0.1 mg/kg IV/IO/IM/SC/IN every 2 min PRN (max 2 mg). IV Infusion:
0.002-0.16 mg/kg/hr.
N-acetylcysteine:
= N-acetylcysteine antidote for acetaminophen poisoning.
— Foradults & pediatric:
+ 1% dose: 150 mg/kg IV over I hour.
+ 2" dose: 50 mg/kg IV over 4 hours.
= 3" dose: 100 mg/kg IV over 16 hours.
Calcium chloride: 10% /10 ml + 27.2 mg/mL elemental Ca.
= Calcium chloride antidote for Calcium channel antagonists toxicity.
— Pediatric Dose: 0.2-0.25 mL/kg IV.
— Adult Dose: 10 mL IV.
= Calcium gluconate used in Hypermagnesemia, Hypocalcemia. (see more before)
— Pediatric Dose: 0.6-0.8 mL/kg IV.
— Adult Dose: 10-30 mL IV.
12. Dextrose (glucose): 40 % /20ml
= Dextrose 40/50 % antidote for hypoglycemia due to insulin/Oral hypoglyce mic over dose.
— Pediatric Dose: 0.5 gram/kg IV.
— Adult Dose: 1 gram/kg IV.
13. Octreotide: 50 or 100 ug /0.5 ml.
= Octreotide antidote for hypoglycemia due to Sulfonylureas (oldest class of oral antidiabe ti
agents) toxicity.
= 50g SC q12h, 5-10 ug/kg/24 hr IV.
14. Digoxin Fab:
= Digoxin Fab antidote for digoxin toxicity.
— Pediatric Dose: 1-2 vials IV.
— Adult Dose: 5-10 vials.
FIRST DRAWER
E. Antidotes drugs
15. Glucagon: vial
= Glucagon antidote for Calcium channel blockers & ß-Blockers toxicity.
— Pediatric Dose: 50-150 meg/kg IV.
— Adult Dose: 3-10 mg IV.
16. Methylene blue:
= Methylene blue antidote for Oxidizing toxins (e.g., nitrites, benzocaine, sulfonamides).
— Pediatric Dose: 1-2 mg/kg IV.
— Neonates: 0.3-1.0 mg/kg IV.
— Adult Dose: 1-2 mg/kg IV.
17. Pyridoxine:
= Pyridoxine antidote for Isoniazid, Hydrazine € Gyromitra esculenta toxicity.
— Adult & Pediatric Dose: Gram for gram if amount isoniazid ingested is known.
— Pediatric Dose: 70 mg/kg IV (maximum 5 grams).
— Adult Dose: 5 grams IV.
B. Hydroxocobalamin:
= Hydroxocobalamin antidote for Cyanide & Nitroprusside toxicity.
— Adult & Pediatric Dose: 70 mg/kg IV (maximum 5 grams). Can be repeated up to 3 times.
Administer with sodium thiosulfate.
FIRST DRAWER
E. Other drugs
Tetanus toxoid (vaccine) & Antitetanus serum:}
Recommendations for Tetanus Prophylaxis
en = Clean Minor Wounds All Other Wounds +
Tetanus Toxoid + Tetanus Toxoid +
<3 or uncertain doses | Yes |No | Yes |
23 doses | Last dose within 5 y
| Last dose within 5-10y
Last dose >10
No
Yes
Tetanus immune globulin Tetanus toxoid
* | Especially if wound care delayed (> 6 h), deep (> 1 cm), grossly contaminated, exposed to
saliva or feces, stellate, ischemic or infected, avulsions, punctures, or crush injuries.
+ | Tetanus toxoid: Tdap if adult and no prior record of administration, otherwise tetanus -
diphtheria toxoid if >7 years and diphthe ria-tetanus toxoid if < 7 years, preferably
administered into the deltoid.
Tetanus immune globulin: adult dose, 250-500 IU adi
immunization
ered into deltoid opposite the
++
SE POR ae
FIRST DRAWER
E. Other drugs
Halodol 5 mg.
Phenytoin 15-20 mg/kg, loading does at 50 mg/min IV.
Glucose: 50% 0.5-1 g/kg.
Dexamethasone: 8mg/Iml.
Diphenhydramin AMP (Anti allergic)
La 20mg
Nitroglyce rine: (Nitroprusside) 50mg/10ml.
Streptokinase (original) 1.500000 u vials, Use thrombolysis in:
A. Acute myocardial infarction with ST segment elevation myocardial infarction (STEMI):
Stre ptokinase 1.500000 u with 50 cc Isotonic NS by Syringe-pump infusion > during one hour with
monitoring BP & HR/10 minutes ifthere is no conti ca
B. Thick & located empyema pleural effusions post chest tube: injected by thoracic surgeon,
pulmonologist, or interventional radiologist into the pleural space in an attempt to dissolve
adhesions and allow fluid to drain freely.
10. KCL 20 mEq/Sml
11. Heparin.
3. SECOND
DRAWER for (Breathing and Airway) :
BYM.
Stethoscope.
02 Nasal cannula, O2 face masks, Venturi masks multiple size & Non-rebreathing mask.
Laryngoscope: Handle with multiple size of Blade : Miller Blade (straight blade) multiple size
and Macintosh Blade (curved blade) multiple size
Intravenous (IV) Line or Catheter multiple size € Intraosseous line and catheter (In older
children and adults in Distal radius and ulna or Proximal tibia)
Pressure Bag (Pressure Pump) Blood pump)
Alcohol swabs.
Blood sets & IV fluid sets.
Central Venous Line multiple size & CVP measurement.
Blood sampling tubes.
Syringes multiple size.
Bedside Glucometer.
Arm-boards (Intravenous Board) 1 long, 1 short & Restraints.
5. FOURTH DRAWER for Circulation IV solutions and tubing:
Ringers Lactated 500 ml
Normal saline 500 ml
D5W 500 ml
6. FIFTH DRAWER for Cardiac, Chest Procedures:
Electrodes.
Masks and eye protection.
Chest Tube with Water Seal chest drain.