Dadimadi Ghrita- a herbal formulation ppt

It is an herbal formulation useful for pandu (anemia). These PowerPoints mention various references, uses, indications, research updates, etc.

1. Dadimadi Ghrita Presented by Dr Anjali Gambhava 2 nd yr P.G Scholar R.S.B.K. Department, PIA.

2. Introduction Main references Ingredients Method of preparation Various references Indications Properties of drug Discussion Research updates Market Availability References Content

3. Sneha + Kalpana Sneha : Fat or Fatty Materials Kalpana : Pharmaceutical process of medicaments E.g. ghrita and taila kalpana Ghritas are in preparation in which ghee is boiled with prescribed kashaya and kalka of drugs according to formula. This process ensure the absorption of the active therapeutic principles of the ingredients used. Introduction

4. Charaka samhita chikitsa sthana : pandu rogadhikara Astanga hridya chikitsa sthana : pandu rogadhikara Bhaishjya ratnavali prathama bhag : prameha chikitsa Bhavprakasha dwitya bhag : prameha pidika rogadhikara Reference

5. Astanga hridya / Charak samhita

6. Ingredients

7. Ingredients Latin name Dadima Punica granatum Dhanyaka Coriandrum sativum Chitraka Plumbago zeylanica Sunthi Zingiber officinale Pippali Piper longum

8. Method of preparation

9. Dadimadi ghrita (B.R/B.P)

10. Kalka dravya Sneha dravya Drava dravya Dadimabija , vidanga , tandula , haridra , chavya , jiraka , haritaki , bibhitaki , amalaki , sunthi , pippali , goksura , yamani , dhanyaka , vrksamla , pippalimula , badar twak , saindhav lavana - each 1 karsha Ghrita - 1 prashtha ( 768 gms ) Jala - 4 prashtha (3.72 lit) Ingredients

11. Dadimadi ghrita ( bruhat ) B.R. 37

12. Kalka dravya Kwath dravya Sneha dravya Drava dravya Dadima , chavya , jiraka , vidanga , haridra , daru haridra , draksha , khajura , yunjata ( munja mula ), nila kamal , gaja pippali , ajmoda , maha nimba tawak , kakoli , sunthi,vacha , devdaru , chavya , kustha , gambhari , yasthimadhu , sariva , indravaruni , murva , vansalochana , karkatasrngi , dhanyaka , kulattha,mahameda , nimba , bruhati dwya , sahadevi , triphala , vasamula , saptala , nirgundi patra - each 5 gms Dadima - 64 pala water- 12 lit. reduced up to 3 lit. Go ghrita - 1 prastha (768 gms ) Jala - 3 lit Ingredients

13. Dadimadi ghrita ( mahat ) B.R. 37

14. Kalk dravya Sneha dravya Drava dravya Kwatha dravya Draksha , khajura , triphala , renuka , asta varga ( meda , maha meda , kakoli , kshir kakoli , jivaka risbhaka , ruddhi , vruddhi ), nisha dwya , bimbi phala , kustha , ela , vidari kanda , ati bala , su shilajatu , twaka , ushira , abhraka bhasma - each sardha pichu - 1.5 karsha Go ghrita - 1 prastha Go dugdha - 1 prastha Water- 3 lit. Dadima , yava , kulattha , satavari - each 1 prastha , water for decoction -12 lit. reduced 3 lit. Ingredients

15. Indications (According to charak / Astang hridya )

16. According to bhaishjya ratnavali / bhavaprakash

17. Drug Rasa Guna Virya Vipaka Karma Dadima M, A, Ks Laghu , snigdha Ushna Madhura Tridoshhara Dhanyaka Ks, T, M,K Laghu , snigdha Ushna Madhura Tridoshhara Chitraka K Laghu , Ruksha , Tikshana Ushna Katu Kaphavata Samaka Sunthi K Guru, Ruksha Ushna Madhura Kaphavata Samaka Pippali K Laghu , Snigdha , Tikshna Anushna sheeta Madhura Tridosh hara Properties of drug

18. As Dadima is madhura rasatmaka , the recipe prepared from it became palatable by pregnant women. Shunthi is amapachaka as well dhanyaka possesses dipana and pachana properties along with chitraka – agnimandyahara which helps to break dosha-dushya complex. Most of the herbs from this recipe acts on digestive systems. In anaemia in pregnancy, there is mainly pitta vitiation. Dadima possesses laghu and snigdha properties; madhura , kashaya and amla tastes; madhura vipaka and anushna veerya . It does pittashamana by madhura and kashaya tastes. Dhanyaka is laghu and snigdha properties;kashaya , tikta and madhura rasa; madhuravipaka and ushnaveerya . hence it is tridoshahara , ushna = vatashamana ; kashaya , tikta , madhura = pittashamana , tikta , katu , ushna = kaphashamana . Being antidypsetic , digestive, astringent, liver stimulant and anthelmintic – its useful in emesis, anorexia and indigestion. Bhavaprakasha has described it as it alleviates pitta . Chitraka holds tikshna , laghu , ruksha – properties; katu , tikta – tastes’ katu vipaka and ushna veerya . Because of that it alleviates kapha-vata , but increases pitta , but here it is processed with cow ghee, hence its pitta vardhaka property is reduced. It enhances the circulation of gastric mucus membrane, thus helps in digestion and absorption. Discussion

19. Shunthi contains laghu and snigdha – properties; katu – taste; madhura vipaka and ushna veerya . Bhavaprakasha has described its use in pandu . It helps in alleviating vata-kapha and pitta . It is appetizer and digestive, hence acts as amapachaka . Pippali acquires laghu , snigdha and tikshna – properties, katu – taste, madhura – vipaka and anushna-sheeta veerya . Hence it balances kapha - vata . Being katu taste and madhura vipaka , it acts on raktadhatu , enhances raktadhatvagni and raktadhatu . It is a good rejuvenator of rakta dhatu . Therefore it is used in this recipe which is useful for anaemia in pregnancy. Ghrita is rasayana and balya , hence its given strength in pregnancy. Thus as a whole this recipe breaks dosha-dushya complex in anaemia in pregnancy and helps to restore health which is ultimately useful for proper nourishment of foetus as well as mother.

20. Effect of Dadimadi Ghrita in Garbhini Pandu (Anaemia in Pregnancy) – IJPRA- August 2023 Dr. Bhagyashree Shinde , Dr. Amit Shinde Conclusion : Dadimadi ghrita has good effect on anaemia in pregnancy which was helpful to increase Hb % as well it was helpful in reducing pandutva (faintness in colour of nails, eyes and skin), pindikodveshatana (pain in calf muscles), hridspanda (increased heart rate), akshikutashotha (swelling around eyes) and klama (fatigue). As well this drug has illustrated good effect on agni (digestive power) and nourishment of pregnant woman without any side effects to foetus and pregnant woman. Research updates

21. Clinical Efficacy and Safety of Punarnavadi Mandura and Dadimadi Ghrita in the Management of Iron Deficiency Anemia : A Prospective Open-label Multicenter Study July 2017 - Journal of Research in Ayurvedic Science Rajesh Sannd Dose: 500 mg tab BD punarnavadi mandur 10 gms BD dadimadi ghrita for 12 weeks Conclusion: At the end of 12 weeks, compared with baseline, statistically significant increase was observed in mean serum iron level (p-value = 0.005). However, mean change from baseline to 84th day in hemoglobin level (p-value = 0.325) was not significant. A significant improvement in symptoms of anemia ,

22. A Comparative Clinical Study of the Effect of Dadimadi Ghrita and Ferrous Sulphate in Management of Garbhini Pandu w.s.r . to Anaemia in Pregnancy Dr Neetika Gautam , Dr Jolly Saxena International Journal for Multidisciplinary Research- Nov.- Dec- 2021 Result : The haemoglobin of all the patients who were enrolled in the study was found to be decreased (Between 8gm% to 10gm%), thus the data of all 55 patients has been put to calculation and analysis. When DG and FS was given to the patients, haemoglobin level was increased in all the patients of both the groups. In few patients the rise in Hb % was between 1.0gm% to 1.5gm% (5 patients). In 45 patients the rise in Hb % was between 1.6gm% to 2.5gm%. Both DG and FS increased Hb % in comparable and almost parallel manner. Only in one subject the rise in Hb % was more than 3gm% and this subject belonged to FS group.

23. A COMPARATIVE CLINICAL STUDY OF DADIMADI GHRITA WITH MANDUR VATAK AND VYOSHADHI GHRITA WITH HARITAKYADI GUTIKA IN THE MANAGEMENT OF PANDU ROGA W.S.R TO IRON DEFICIENCY ANEMIA Dr. Dhanalaxmi R. Sampaganv World Journal of Pharmaceutical Research- 10 th march 2023 Group A DG 10 ml+ mandur vataka 500 mg BD 2 times Group B VG 10 ml + Haritkyadi Gutika 250 mg BD 2 times Conclusion: In the present study of clinical trials of Dadimadi Ghrita with Mandura Vatak and Vyoshadhi Ghrita with Haritakyadi Gutika in Pandu , Group B has better effect than Group A.

24. Market availability 165 /- rs

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