Dentinogenesis

Process of Dentinogenesis explained. Courtesy Ten Cates and James Avery

1. Dentinogenesis
Dr. Syed Sadatullah
Assistant Professor

2. Dentinogenesis
The formation of dentin is called dentinogenesis, which
starts before amelogenesis
Dentin is formed by odontoblast cells
Dentinogenesis takes place in two phases: first the
formation of organic collagen matrix and second the
deposition of hydroxyapetite crystals
At the beginning of dentinogenesis the odontoblast elongate
resulting in the formation of Tomes fibres or odontoblastic
processes
Dr.Syed Sadatullah

3. Morphological changes in odontoblasts during dentinogenesis
Dr.Syed Sadatullah

4. Dr.Syed Sadatullah
Odontoblasts then secrete matrix protein at the apical end
of the cell and along its process
The secreted matrix is collagenous and not mineralized
hence it is called predentin
As the matrix is being secreted the odontoblasts move
towards the centre of the future pulp
The matrix that forms around the elongated cell process
eventually mineralizes and the odontoblastic process will
lie within a dentinal tubule

5. As each day passes predentin is formed along the pulpal
boundary, the adjacent predentin that was formed during
the previous day mineralizes and becomes dentin
During the period of crown development approximately
4µm of dentin is laid down in every 24 hours
Incremental deposition and mineralization of dentine
begins below the cusps, at the tips of the pulp horns at the
DEJ
Dentinogenesis continues life long but slows down after the
tooth is completely erupted
Dr.Syed Sadatullah

6. Formation of enamel and dentine in increments
Dr.Syed Sadatullah

7. Odontoblasts in dentinal tubules
Dr.Syed Sadatullah