Consideration D. The occurrence of MDD is not better explained by schizoaffective disorder, schizophrenia, schizophreniform disorder, delusional disorder, or other unspecified
Consideration
Risk and Prognostic factors Temperamental Environmental Genetic & Physiological
Development & Course Onset: Before age 10 years Not Apply to before 6 With chronic irritability, more prone to unipolar depression more common to adolescents Course Chronic Severe Non episodic
Development & Course: Early and insidious (Childhood, adolescents, early adult life) Chronic course Early onset associate with comorbidity (Substance and personality disorder)