Development of heart and formation of heart.pptx

Heart development with valve and wall formation stages

1. Development of heart Presented by – Group 07 Presentation on Chitkara Business School Dept. of Healthcare Management

2. Introduction M esodermal origin M esenchymal cells in cardiogenic area form 2 angioblastic cords These cords become canalized to form 2 endothelial heart tubes and these 2 tubes futher fuse to form a single endothelial heart tube . 2

3. 3 Linear heart Single endothelial heart tube shows dilatations Bulbous cordis Ventricle Atrium Sinus venosus

4. 4 Segmentation of heart tube and their fate

5. 5 Cardiac looping BULBUS CORDIS Lies at the arterial end of linear heart tube C ranial most part of linear heart SINUS VENOSUS V einous end of the heart Has left and right horns(elongations of sinus venosus)

6. Formation of Atria 6 AV canal divides into 2 halves i.e. right and left 2 AV cushions appear on dorsal and ventral walls T hey grow towards each other and fuse, these fused cushions form septum intermedium or atrio ventricular septum Formation of atrio ventricular septum or septation of atrio ventricular canal

7. Formation of Septum spurium 7 Right and left venous valve join to form of septum spurium

8. Formation of atrial septum 8 Atrial chamber undergoes division into right and left by formation of 2 septa Septum primum Septum Secundum

9. Formation of atrial septum 9

10. Separation of aorta and pulmonary trunk 10 Spiral Septum appears within truncus arteriosus and subdivides it into ascending aorta and pulmonary arteries. They fuse along the axis of the cylinder extending down towards the ventricles. Interventricular foramen obliterated by mass of endocardial tissues from interventricular septum, endocardial cushions & Spiral Septum.

11. Development of ventricles (interventricular septum) 11 Conus of bulbus cordis merge with cavity of primitive ventricle. Interventricular septum grows upwards from the floor of bulbo ventricular cavity & divide it into right & left halves. 2 ridges (right & Left bulbar ridges) from the wall of the conical part of bulbar cavity (Spiral septum), grows towards each other and fuse form bulbar septum. The gap between upper edge of interventricular septum and lower edge of bulbar septum, is filled by proliferation of tissues from atrioventricular Cusions.

12. Exterior of Heart 12 Heart tube is suspended from the dorsal wall of the pericardial cavity which constitude dorsal mesocardium. Caudal part of the heart tube (atrium, sinus venosus) is embedded within the septum transversum Bulbus cordis and ventricle in pericardial cavity grows rapidlv & becomes folded to form U-shape Bulbo-ventricular loop.-The atrium and sinus venous freed from septum transversum. Arterial and venous ends come closer to each other and the space between them becomes the transverse sinus of pericardium.

13. Development of Heart Valve 13 Formed by proliferation of connection tissue under endocardium of left and right atrioventricular canals. There are 2 pairs of atrioventricular valves A pair of atrioventricular valves Tricuspid and Bicuspid valves are proliferation of connective tissue under endocardium of the right and left atrioventricular canals. A pair of semilunar valves Aortic and pulmonary valves derived from endocardial cushion that are formed at the junction of the truncus arteriosus and conus cordis.

14. Development of Heart Valve 14

15. Conduction system of Heart 15 The heart is able to contract on its own because it contains specialized cardiac muscle tissue that spontaneously forms impulses and transmits them to the myocardium to initiate contraction. The conducting system of the heart is composed of the following five components Sinuatrial Node (SA Node) Atrioventricular Node (AV Node) Atrioventricular Bundle (of His) Left and right branches of bundles (of His) Subendocardial Purkinje fibres

16. Thank You 16