Dextran.pdf

Biochemistry

1. POLYSACCHARIDES
Homopolysaccharides
Storage
homopolysa
ccharides
Structural
homopolysa
ccharides
vStarch
vGlycogen
vDextrin
vGlycogen
vInulin
vCellulose
vChitin
Heteropolysaccharides
Mucopolysaccharides or GAG’s
vHyaluronic acid
vChondroitin sulfate
vHeparin
vKeratansulfate

2. DEXTRAN
vThese are highly branched homopolymers of glucose units with 1-6,1-
4, and 1-3 linkages
vThese are produced by micro organisms
vTheyhave molecular weight 1 million to 4 millions
vTheyarehighly inert
vUsedinpreparation of gels in SDS-PAGE
vIt isoftenadministered through intravenous infusion as plasma volume
expander in the treatment of hypovolemic shock

3. DEXTROSE, DEXTRIN AND DEXTRAN ARE DIFFERENT
DEXTROSE
D-glucose is otherwise
called DEXTROSE, a
term often used in
bed-side medicine,
eg:dextrose drip
DEXTRIN
It is the partially
digested product of
starch
DEXTRAN
It is high molecular
weight carbohydrate,
synthesized by
bacteria