Differences between Oral glucose tolerance test and Oral glucose challenge test

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1. outline Introduction History of OGTT and OGCT OGTT and indications OGTT procedure and result interpretation OGCT and it indications OGCT procedure and result interpretation Gestational diabetes Contrast between OGTT and OGCT Conclusion References 10/7/2020 2

2. Introduction 10/7/2020 3

3. H istory OGTT and OGCT 10/7/2020 4

4. OGTT OGTT is a test that access the body ability to tolerate a measure quantity of glucose. Rate of glucose absorption, ability of beta cell to secret insulin and property of the insulin to decrease blood glucose level determine the extent of glucose tolerance. 10/7/2020 5

5. 10/7/2020 6 Indications

6. Patient prep The patient is instructed to eat good carbohydrate diet for 3 days prior to the test . The patient should avoid some certain drugs for 2 days prior to the test Patient should avoid smoking. Streesful exercise is to be avoided prior to test The will fast over night. 10/7/2020 7

7. procedure 10/7/2020 8

8. Result interpretation Fasting plasma glucose should be less than 5.6 mmol /L. value between 5.6 and 6.9 mmol /L indicate pre-diabetes, and value above 7.0 mmol /L are diagnostic of DM For 2 hour GTT; glucose level below 7.0 mmol /L is normal and value above 10 mmol /L confirm a diagnosis for DM Glucose level between 7.8 and 11.1 mmol /L indicate “impaired glucose tolerance” 10/7/2020 9

9. OGCT It access the ability body to clear off a measure dose of glucose in a specific time. OGCT is a random test. It is done between 24 th to 28 th week of pregnancy . 10/7/2020 10

10. Indication 10/7/2020 11

11. OGCT procedure and result interpretation Patient is ask to drink 50mg of glucose solution. Blood is drawn 1 hour later for glucose estimation. Result interpretation Glucose level <140mg/ dL (7.8 mmol /L), is negative no further test needed. The test is positive if glucose level is >140mg/ dL (7.8mmol/L), and OGTT will be done the next day to confirm GDM 10/7/2020 12

12. Gestational diabetes (GDM) GDM, is a type of diabetes which develops during the pregnancy This occure as a result of placental hormones (progesterone , Placental lactogen , growth hormone and corticotropin releasing hormone) interferances with Insulin action . 10/7/2020 13

13. Complications of GDM 10/7/2020 14

14. Differences between OGTT and OGCT 10/7/2020 15