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Tract 3

1. Digestive Tract 3

3. Major layers and organization of the digestive tract

4. Small Intestine

7. Celiac disease (celiac sprue) is a disorder of the small
intestine mucosa that causes malabsorption and can lead to
damage or destruction of the villi. The cause of celiac
disease is an immune reaction against gluten or other
proteins in wheat and certain other types of grain. The
resulting inflammation affects the enterocytes, leading to
reduced nutrient absorption.

8. Duodenal (Brunner) glands

9. Brunner's Glands - only region of the
gastrointestinal tract (along with the esophagus)
with glands in the submucosa.

10. Gastroduodenal
Junction
The stomach and the duodenum are composed of the four
layers characteristic of the gastrointestinal tract. However,
pyloric glands are located in the mucosa whereas the
duodenal glands are located in the submucosa.

11. Circular folds (plicae circulares) of the jejunum

12. Enterocytes

13. Goblet cells

15. Enteroendocrine cell

16. Enteroendocrine cells

17. Paneth cells

19. Peyer's Patches - diffuse aggregations of lymphoid cells in
the lamina propria.

20. M (microfold) cells

22. Microvasculature, lymphatics, and muscle in villi

23. Small Intestine

24. Large Intestine

25. large intestine

26. Wall of the large intestine

28. Hemorrhoids
Swollen blood vessels in the mucosa or submucosa of the anal
canal can cause a painful disorder called hemorrhoids. This
common condition typically results from a low-fiber diet,
constipation, prolonged sitting, or straining at defecation,
conditions that produce increased pressure on these blood
vessels.

29. Colon mucosa

30. Colon
Auerbach's (or Myenteric) Plexus -
provides motor innervation
of the muscularis externa.

31. Colonocytes
Mucosa of the rectoanal junction

32. Rectum
This specimen is from the rectum as it narrows approaching the
anal canal.

33. Recto-Anal Junction
The anal canal is the site where there is a transition from
the simple columnar epithelium of the colon to the stratified
squamous epithelium of skin.

34. Sebaceous Glands
Stratified Squamous Epithelium

36. Summary of distinguishing digestive tract features, by region and
layers.

37. Thank You!