Our Infrastructure
•Built-In Expertise
o>20 experienced members of customer support team including clinical physicists
o>30% of Sun Nuclear is dedicated to Research and Development
o>15 AAPM Task Group memberships including TG-142, TG-016, and TG-100
•Systems
o CE & ISO Quality Management System (QMS)
o9 FDA 510(k) clearances
oThree Radiation Bunkers
–Varian 21EX
»Customer training in the Sun Nuclear Training Center
–Clinac 2100C, 80 leaf MLC (X: 6,15; e: 6,9,12,15, 18)
»Research & Development
–Cobalt 60, 2000 Ci
»Manufacturing tests
•Vertical Integration
oCore competencies include R&D, manufacturing, radiation test, Sales/Marketing
Sun Nuclear Training Center
•Industry focus on proper training to comply with requirements
•5,000 sq ft facility located in Melbourne, FL
oLecture hall comfortably seats 60
oControl console connected to 65- and 80-inch monitors
oFully commissioned linac and TPS
oBunker modeled after a clinical setting
Leading Technology
•The Right Detector for the Right Application
oManufacturer of both diode and ion chamber arrays
oSunPoint® Diode detectors
–Offering smaller volume, better sensitivity, less drift and increased lifetime
•Fast Setup
oPortable and lightweight
oSingle power/data cable
oNo pre-irradiation or warm up required
•Increased Efficiencies
oDevice integrated electrometers
oUser performed array calibration
•Convenient Product Licensing
oUnlimited computer stations per product
license (where applicable)
oInternet downloadable – no waiting
oProduct license files work on all computers
–No computer specific codes
Independence & Transparency
SNC Data File
•Sun Nuclear software
oSolutions are independent of planning and delivery vendors
–Proper checks and balances
oSun Nuclear owns and maintains all of its own code base
–No “black boxes”
–All algorithms documented in online help
–Ensures prompt customer service
•Sun Nuclear data
oMeasurement based
oOpen format for export and analysis
oOriginal raw and processed data
•25 Detectors:
oOutput, flatness, symmetry, energy and field size
•No additional buildup required
•Ion chambers and diodes
•Automatic temperature & pressure correction
•Real-time wireless option
•Only one entry into room
•Software included
oWith trend analysis database
An advanced tool for daily quality assurance of a radiation therapy beam
•The Daily QA 3™ uses both ion
chambers & diodes
oRight detector for the right application
•Daily QA 3™ has 25 detectors:
o5 chambers for flatness/symmetry
o4 chambers for electron energy checks
o4 chambers for photon energy checks
o12 diodes for light-radiation
coincidence
Detector Geometry
•Measurements at multiple depths
oEntrance and exit measurements
•Central 10x10 contains ~221 detectors
o442 detectors with ‘Merge’ feature
•Detectors are arranged on a HeliGrid™
oIncreases BEV data density and reduces detector overlap
SunPoint® Diode Detectors
•Reproducibility
Short term: +/- 0.15% (15 consecutive 60 cGy
fields)
Long term: +/- 0.2% (9 month period)
Sensitivity change: < 0.5%/kGy at 6MV,
1.5%/kGy at 10 MeV
User calibrated in only 15 minutes (typically
every 12-18 months)
•Sometimes, smaller is better
More than 4500 times smaller than ion
chambers
Allow TRUE point to point comparison with the
TPS calculated dose
Offer 10 times or more sensitivity than ion
chambers – despite small size
Measure in Absolute Dose with no warm-up
time required
•ArcCHECK features a versatile central cavity
oMay be used to accommodate different detectors and inserts
oMultiPlug
TM
(left) also accommodates EBT film cassette and up to 25
unique locations including isocenter, measuring every pulse
Central Cavity Options
Why in vivo dosimetry?
“A quantification of the effectiveness of EPID dosimetry and software-based plan
verification systems in detecting incidents in radiotherapy”
Bojechko C, Phillips M, Kalet A, Ford E.C.
Department of Radiation Oncology, University of Washington
Med Phys 42(9), Sept 2015
•C Study over 2.5 years of all failure modes 4437 Patients - 343
incidents rated “potentially severe” or “critical –
•Pre-Tx EPID dosimetry detected 6% of errors (physics calculation
errors, treatment machine error, and corrupted plans) – all modes with
low number of occurrences
•First Fraction in vivo QA detected 74% of all failures – incidents with the
highest occurrence (patient setup, CT dataset errors)
“The most effective EPID-based dosimetry verification is in vivo
measurements during the first fraction”
•All Fraction in vivo QA added the ability to detect other common errors
(movement on the table, treatment machine error, and setup errors)
“In vivo all fraction dosimetry gives an added benefit to 20% of events”
First fraction in vivo
Why PerFRACTION
TM
?
Industry Challenges to overcome to by SNC’s 30 R&D Physicists and
Engineers to ensure a comprehensive and Fully automated solution
for patient treatment QA.
•Take the patient into account =Hundreds of images every day
•Automated
•Independent
•No additional time clinical workflow, and minimal impact to the review
team
•Therapists and Physicists
•Robust
•Able to Determine both Patient and Machine Deviations
oChanges to patient anatomy
oMLC drift
oDifferences in gantry rotation or linac output
Delivery Error Sensitivity
1
“Monitoring daily MLC positional errors using trajectory log files and EPID measurements for IMRT and VMAT deliveries,” A. Agnew, et al., 2014 Phys. Med. Biol. 59 N49
2
Varian Field Safety Notice CP-12459, July 2014
The “New Way”
oReturns to the true intent of the second calculation -
verifying patient dose
oInput - RT Plan data from TPS
oReconstructs patient dose in 3D using CCCS algorithm
oDisplays Planned vs. Calculated:
–Point Dose calculations (including points of interest in
plan)
–DVH
–3D Dose comparison
–Clinical Goals/protocols
MU vs Dose Calculation
SNC Machine Dashboard
•Presents all recently executed tests. Failed tests are highlighted red.
Approve the tests from the dashboard or click the test to drill down and
scrutinize the results.