Page 1 of 7 Paul C. Chikezie
Paul C. Chikezie Ph.D.; FHEA
Coventry, England, United Kingdom, CV2 4HT |??????+447985292250
??????
[email protected] |
[email protected]
Professional Profile |?????? RESEARCHGATE | GOOGLE SCHOLAR | ORCID ID | LINKEDIN | SCOPUS
Industry: Education & Instruction, Scientific Research & Development:
Senior Teaching Fellow in Biomedical Science at Coventry University, England, United Kingdom (2023 – 2025)
and a Fellow of the Higher Education Academy (FHEA); Appointed Professor of Medical Biochemistry at Imo
State University, Owerri, Nigeria (October, 2017); Endorsed by the Royal Society (UK, 2024) as a global
scholar of exceptional talent in biochemistry and academic leadership; Research Scientist/Lecturer and
Administrator at Imo State University (2000 – 2023); over twenty-five (25) years of research and cognitive
experience in academia with one hundred and forty (140) scholarly publications. Served as the Head of
Department (HOD) of Biochemistry, and Associate Dean of the Faculty of Biological Sciences; Proficient in
teaching and research in biomedical science:- bioenergetics & intermediary metabolism, enzymology, molecular
pathophysiology/diagnostic biochemistry, target internal organ toxicity assessment, cell & molecular biology,
haemoglobinopathies, and related topics. Multiple grants recipient and Principal Researcher/Investigator of the
Tertiary Education Trust Fund (TETFund) Institution-Based Research Intervention Programme; serving as an External
Examiner of postgraduate programmes, External Assessor for professorial promotion, Course/Module Facilitator,
and Visiting Professor at various universities overseas: Committed to inspiring the next generation of professionals
through engaging lectures and hands-on laboratory instruction
Summary of Core Competencies
Curriculum design & academic programme development
Quality assurance & academic governance (Moderator, CQEM)
Module leadership across biological & biomedical science domains
Student-centred teaching using inclusive & technology-enhanced methods; audio-visual technology
Blended learning approach- lectures, seminars, practical sessions, and student-led discussions
Mentoring & pastoral care (academic adviser to 400+ students)
Research supervision at undergraduate & postgraduate levels
Implementing university research projects and publishing in reputable scientific journals
Interdisciplinary Expertise: nutrition/food biochemistry, structure & biocatalysis, biosignaling,
bioactive compounds (natural products), toxicology/biochemical pharmacology
Specific Analytical Skills for Laboratory Project Supervision
Extraction, isolation, identification and characterization of bioactive compounds/plant natural
products (PNPs) for biological and pharmacological screening and metabolite profiling:
Analytical protocols and instrumentation: Polarity Extraction, Thin-Layer Chromatography (TLC), Column
Chromatography, Sephadex Chromatography. Spectroscopic techniques: Ultraviolet-Visible (UV-VIS)
and Infrared (IR) spectrophotometry- PerkinElmer Spectrophotometer, USA and Gas Chromatography-
Mass Spectrometry (GC-MS)-Agilent Technologies, Inc., USA, Fourier Transform-Infrared Spectroscopy
(FT-IR)- PerkinElmer, USA and Hyphenated Techniques e.g. LC-UV.
Medicinal/therapeutic bioactive compounds and pathophysiology (preclinical studies):
Measurement of therapeutic benefits of bioactive compounds in hyperlipidaemia/dyslipidemia,
atherogenicity, – blood lipid profiling, hyperglycaemia/diabetes mellitus, methaemoglobinemia, sickle
erythrocyte membrane destabilization and sickle haemoglobin (HbS) polymerization – biophysical
analyses using rodent and in vitro models; Erythrocyte MCF index and MetHb% using GC-MS, FT-IR
and UV-VIS spectrophotometry.
Broad skills in cell biology and chemistry:
Use of erythrocyte enzymes, notably, glutathione S-transferases, NADH-methaemoglobin reductase,
lactate dehydrogenase and system metabolites (GSH/GSSG ratio, MDA, bilirubin, urea, uric acids,
creatinine, electrolytes, cholesterol, TAG, etc.) as bio-indicators in pathology using rodent and in vitro
models, GC-MS, FT-IR and UV-VIS spectrophotometry. Isolation and separation of plasmid DNA digest
using the Qiagen plasmid miniprep kit and agarose gel electrophoresis.
Preclinical diagnostic pathology (enzymology & histology):
Diagnostic use of enzyme biomarkers (AST, ALT, γ-GT, ALP, ACP, LDH, etc.) to assess organ and tissue
damage and heavy metal exposure in rodent models using UV-VIS spectrophotometry.
Nutraceuticals and food chemistry applications & toxicology:
Diet supplementation and food processing and hazardous substances in foods, amino acids profiling,
protein efficiency ratio (PER), polyphenol oxidases from food and browning reactions, extraction,
purification and assay of enzymes from foods, organoleptic properties and eliminating toxic substances
(e.g. aflatoxins, cyanogenic glycosides, heavy metals) from foods and wines using UV-VIS
spectrophotometry.