Bhallatakarasayana
By
Dr.Krishika.M,
Dept of Rasayana evamVajeekarana
Kaher’sShri BMK Ayurveda Mahavidhyala,
Belagavi, Karnataka.
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Introduction:
➢Bhallataka: SemicarpusAnacardium
(Seimeion-Marking/ Tracing; Carpus-Nut; Anacardium-Heart-shaped)
➢Named as Marking nut.
➢It is considered under Upavishaand phalavisha
➢CharakaAcharya have explained bhallatakarasayanaas Urjaskaraand Susrutha
highlightenedits use as a Naimittikarasayana.
➢Bhallatakarasayanayogasin bruhattrayis.
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➢Bhallataka
➢Veervrikshya
➢Ruksha
➢Agnimukhi
➢Dhanu
➢Agnika
➢Veertaru
➢Krimighna
➢Tailabeeja
➢Arushkara
➢Agnivakrak
➢Tapana
➢Dahana
➢Bhalli(corrosive)
➢Shophakrita
➢Anala
➢Vranakrita
➢Shophahetu
➢Sphotabeejaka
➢Vahni
Synonyms:
In Charakasamhitaone of the cause of
Agantujashotha(exogenous swelling) is
contact of fruits or flowers of
Bhallatakawith body.
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Rasa panchaka
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Shodhana:
Poisonous plants are subjected to shodhanasanskara(purification process), before its
therapeutic useto reduces toxicity levels.
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भल्लातकाननपुष्टाननधान्यराशौननधापयेत्|
ग्रीष्मेसांगृह्यहेमन्तेथवादुस्थनग्धदहमैवणपुः||६६||
सांथकृत्यतान्यष्टगुर्ेससललेऽष्टौपवपाचयेत्|
अष्टाांशसशष्टांतत्क्वािांसक्षीरांशीतलांपपबेत्||६७||
वधणयेत्प्रत्यहांचानुतरैकैकमरुष्करम्|
सप्तराररयांयावत्रीणर्रीणर्ततःपरम्||६८||
आचत्वाररांशतथताननह्रासयेद्द्वृद्धधवितः|
VardhamanaBhallatakayogam:
8 fruits, increased by one for 3 weeks then increased daily 3 till it attains 40 –Total of 1oo(in 7 weeks)
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Precaution while consuming Formulation of Bhallataka
❑Pathya-Person should consume milk & rice and ghee in large quantity.
❑Varjya(Avoid)-Walking in sun, excess sexual intercourse, exposure to excess heat, Use
of hot water
Contra-indications:
❑Small children,
❑Very old persons
❑Pregnant women
❑Individuals of predominant of Pitta constitution.
❑Summer season
Precautions:
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Pharmacodynamics:
Anti-inflammatory activity
•Methanolic, ethanolic, chloroform, ethyl acetate and
petroleum ether extracts of fruits of SA proved to have
anti-inflammatory activity in albino rats. The extract
showed significant anti-inflammatory activity
comparable to the reference standard aspirin
Antiatherogenic effect •Semecarpusanacardium(SA) shows antioxidant
property. It has capacity to scavenge the superoxide
and hydroxyl radicals at low concentrations. The
process of atherogenesis initiated by peroxidation of
lipids in low-density lipoproteins was also found
inhibited by SA
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•Nuts of SA, extracted with milk,provedmainly for its locomotor and
nootropic activities in different experimental animal models.
Nootropic activity:
Antimicrobial activity•Alcoholic extract of dry nuts of SA (Bhallatak) showed
bactericidal activity in vitroagainst gram negative strains
(Escherichia coli, Salmonella typhi) and two gram positive strains
(Staphylococcus aureusand Corynebacterium diphtheriae).
Hypoglycemiceffect •Ethanolic extract of dried nuts of SA is effective in reducing
blood glucose and investigated in both normal (hypoglycemic)
and streptozotocin-induced diabetic (antihyperglycemic) rats.
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AntispermatogenicEffect
•Semecarpusanacardiumextract feeding caused
antispermatogeniceffect evidenced by reduction in
numbers of spermatogenic cells and spermatozoa in
male albino rats.
Nephrotoxicity
•Significant alteration in activity levels of marker enzymes of
kidney as well as histological structure leading to nephritis
were observed, indicating renal dysfunctioningin albino rat.
Results exhibited nephrotoxicity inducing potential of SA nut
oil extract
Fatal dose:
❑Fatal Dose:
-5-8 seeds
-10 gm –marking nut juice
-10 ml –oil
❑Fatal Period –12-24 hrs
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Signs & Symptoms:
1) Dermal Exposure –When applied to skin, it causes irritation,
inflammation, vesication formation, pain & itching. The blister
contains serum. The skin lesion resembles a contusion. Later on, the
lesion turned into an ulcer with sloughing of skin.
2) Ingestion –causes
i) Blister formation in & around oral cavity
ii) Vomiting
iii) Diarrhea
iv) Abdominal pain
v) Hypotension / shock
vi) Delirium
vii) Coma
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Improper usage:
When manifestation of toxicity observed,
Internal:
❑Medication of Bhallatakais stopped and white albumen of coconut or juice of
leaves of Chincha(Tamarindus indica)
❑Sesamum or coconut is given to eat.
Local application:
❑Local application of paste of tila(sesamum) rubbed with buffalo milk and mixed
with butter
❑Local application of paste of Yashtimadhu(Glycyrrhiza glabra) and
tila(seasamum) rubbed with milk
❑Local application of rubbed Shalapatra(Desmodiungangetictum).
ArushkaraShothaghna
❑Paste of tila(sesamum) with goat milk and butter
❑Krishna mrittika(Black clay) lepa
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Ayurveda Treatment
1) Local –
i) To wash the contaminated part skin with
soap wash
ii) Apply coconut oil on affected part
2) Internally
i) Stomach wash
ii) Use of demulcents
iii) To relieve pain Inj. Morphine –10mg
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Allopathic management:
➢The specific antidote for the toxicity of Bhallatakais Bibhitaka(Terminaliabelerica).
➢The decoction or powder preparations with fruit rind and bark of Terminalia belerica
are effective for the sudden reactions and for systemic effects.
➢Drugs that mitigate Pitta like milk and clarified butter and other drugs with cold
potency may also be used
.
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Antidote:
Five cases of contact dermatitis caused during different stages of shodhanasanskaraof
Bhallatakafruits due to improper handling of utensils and disposal of media used in shodhana
procedure.
Tx: (advised till lakshonopashama–yeidedresults in 20 days)
▪The affected persons were advised external application with pounded Nimba(Azadirachta
indica) leaves on affected parts
▪Internal administration of
Sarivadyasava30 ml thrice daily after food
Triphalachurna5gm before food twice daily.
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Case report:
Medicolegal Aspect:
i) The juice is used as an abortifacient by application to OS uteri by means of an
abortion stick.
ii) It is applied to genitals as punishment for adultery.
iii) It is used by malingers to produce an artificial bruise to support a false charge.
iv) The juice may be instilled into eyes to produce conjunctivitis (vitriolage)
v) Accidental poisoning may occur from internal administration by quack.
vi) The juice like vitriol has been thrown on the face with evil intentions.
vii) Suicidal & Homicidal use is very uncommon.
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Other references
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Anti-cancerous:
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•Leukemia
•Breast Cancer
•Pancreatic
•Hepatocellular Carcinoma
•Epidermoid Larynx Carcinoma
•Cervical Cancer Cell Lines
Discussion
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•Charakaquoted maximum of dose of 1000 bhallatakaand Susrutaas a controversy
advised for upto2000 bhallataka, it can be considered in the point of view of
Swathasyaurjaskara(charaka) and Naimittikarasayana(Susruta)
•Many articles are available regarding the toxicity studies of Bhallatakabut case studies
are less.
•More clinical studies have to be encouraged by following the appropriate safety
precautions
•This is an era of Sedentary lifestyle which pays ways for various kaphapredominant
life style disorders, as this is an excellent drug of choice for the same; many
exploratory studies can be encouraged in future.
•Shende, Dr.(2021). Rasayanakarma of poisonous Bhallataka: A Review. Ayurline: International
Journal of Research in Indian Medicine. 5. 10.52482/ayurline.v5i04.598.
•A TOXICOLOGICAL REVIEW OF BHALLATAKA ( Semecarpusanacardium Linn) by Pawade
Uday Venkatrao
•LlanchezhianR, Joseph C R, RabinarayanA. Urushiol-induced contact dermatitis caused during
Shodhana(purificatory measures) of Bhallataka(Semecarpusanacardium Linn.) fruit. Ayu. 2012
Apr;33(2):270-3. doi: 10.4103/0974-8520.105250. PMID: 23559802; PMCID: PMC3611655.
•SemaltyM, SemaltyA, BadolaA, Joshi GP, Rawat MS. Semecarpusanacardium Linn.: A review.
PharmacognRev. 2010 Jan;4(7):88-94. doi: 10.4103/0973-7847.65328. PMID: 22228947; PMCID:
PMC3249908.
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Thank you!
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Every nectar is a poison if used in excess!