drug of abuse.pptx

Drug of abuse

1. Drug of Abuse Toxicology & Forensic Serology 1 Dr. Aamir Ali Khan Assistant Professor

2. Drug of Abuse 7/6/2021 Toxicology & Forensic Serology 1 The habitual use of drugs Not needed for therapeutic purposes Solely to alter one's mood Affect of state of consciousness, or to affect a body function unnecessarily Continuous use result in physical & medical dependence e.g. cocaine, heroin , alcohol

3. Drug Dependence Toxicology & Forensic Serology 3 Physical Dependence: the body need drugs to feel normal & function properly Body physiology altered & worked satisfactorily if large doses of drugs available The withdrawal symptoms (e.g pain) proof of physical dependence

4. Psychological dependence: There is carving for repeated or compulsive use of drugs to satisfy emotion or personality needs If discontinued result in absence of pleasure but no physical pain 7/6/2021 Toxicology & Forensic Serology 4

5. Psychotropic Drugs: these are drugs that could alter mental function by their action, it include stimulants, depressants, narcotics and hallucinogen. 7/6/2021 Toxicology & Forensic Serology 5

6. Drug of Abuse Hypnotics: these are drugs which produce sleep, e.g. barbiturates Narcotics: these are drugs which relieve pain & produce Sleep e.g. opium, morphine Sedatives: these are drugs which produce a calming effect on central nervous system 7/6/2021 Toxicology & Forensic Serology 6

7. Drug of Abuse Stimulants: drugs which produce wakefulness, alertness by acting on CNS e.g. amphetamine Hallucinogen: these are drugs which produce bizarre effects on mind such as distortion of time, space, sound, color etc e.g. Phencyclidine Street Drugs: these are drugs obtained not from pharmacist but surreptitious sources, it is usually adulterated drugs 7/6/2021 Toxicology & Forensic Serology 7

8. Effect of Stimulants 7/6/2021 Toxicology & Forensic Serology 8 Alertness Increased energy Restlessness Wakeful ness Euphoria Reduced appetite Talkative Increased BP, heart rate and breathing

9. Cocaine Amphetamine Nicotine 7/6/2021 Toxicology & Forensic Serology 9 Stimulants Street name : Crack, Snow , Star dust, Charlie, Nose candy Street name : Black beauties , co-pilots ,crystal meth , heart

10. Effect of Depressants 1 7/6/2021 Toxicology & Forensic Serology Depressant is a substance that reduces the normal body activity, function or an instinctive desire such as appetite for food. It is also known as “downers” Highly addictive Sedating Dizziness Anxiety /hypnosis

11. Alcohol Barbiturate s Cannabis Opioid Depressants Street name : Benzos, Downers, Goofballs Street name : Dope , Painkillers , Oxy 1 1 7/6/2021 Toxicology & Forensic Serology

12. Effects of Hallucinogen 1 2 7/6/2021 Toxicology & Forensic Serology Blurred vision & loss of coordination Increased breathing, heart rate & BP Anxiety, agitation Increased body temperature, feeling numbness euophoria

13. Marijuana PCP (phencyclidine) LSD Hallucinogen Weed & pot, Mary jane, ganga, Street name : Angel dust, love boat, wack,rocket fuel, peace pills Street name : Street name : Acid Battery acid Blotter Boomers hash,herb 1 3 7/6/2021 Toxicology & Forensic Serology

14. Common Sign Of Drug Abuse Drug Dependent Mood Swing 1 4 7/6/2021 Toxicology & Forensic Serology This Photo by Unknown Author is licensed under CC BY- SA- NC

15. Common Sign Of Drug Abuse This Photo by Unknown Author is licensed under CC BY- SA- NC Altered work efficiency Toxicology & Forensic Serology 1 5 7/6/2021

16. Common Sign Of Drug Abuse Injection marks on addict body 1 6 7/6/2021 Toxicology & Forensic Serology

17. Common Sign Of Drug Abuse Stealing items to support Drug habit This Photo by Unknown Author is licensed un d T e r o C x C i c B o Y l - o N g D y & Forensic 1 7 7/6/2021 Serology

18. Common Sign Of Drug Abuse This Photo by Unknown Author is licensed under CC BY-NC- ND Poor Physical Hygiene Toxicology & Forensic Serology 1 8 7/6/2021

19. Drug of Abuse Screening 1 9 7/6/2021 Toxicology & Forensic Serology Detection of one or more illegal substance in urine, blood, saliva, sweat or organ of deceased Testing detects substance normally not found in body Chromatographic technique can be use for screening of multiple drugs (qualitative analysis) Cut off value use for quantitative screening

20. Drug of Abuse Screening 2 7/6/2021 Toxicology & Forensic Serology Positive qualitative screening test considered presumptive Must be confirmed with more specific & sensitive method Gas chromatography/mass spectrometry (GC/MS) or liquid chromatography- tandem mass spectrometry (LC- MS/MS) recommended for medicolegal cases

21. Commonly screened drug classes 7/6/2021 Toxicology & Forensic Serology 1 2 https://labtestsonline.org/tests/drug-abuse- testing dated: 4/7/2021

22. Reference Text book of Medical Jurisprudence, Forensic medicine and Toxicology, BV Subrahmanym Seventh editio https :// labtestsonline.org/tests/drug-abuse- testing 7/6/2021 Toxicology & Forensic Serology 2