ECG_Physiology_17_01_2019.pdf notes for students

health2022carevasu 6 views 195 slides May 13, 2025
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About This Presentation

Ecg noted


Slide Content

Electrocardiogram [ECG]
Dr.Viral I. Champaneri, MD
Assistant Professor
Department of Physiology

1

Learning Objectives
•Definition of ECG
•ECG Paper
•Calculation of heart rate from ECG
•Leads of ECG & recordings from leads
•Einthoven's triangle
•Wave of excitation

2

Electrocardiogram
•Summated effect of
•Action potentials from cardiac muscle
•Can be recorded from the surface

3

Electrocardiogram
•If electrodes are placed
•On the skin
•On opposite sides of the heart
4

Electrocardiogram [ECG]
•Electrical potentials
•Generated by the current can be recorded
•The recording is
•Known as an Electrocardiogram (ECG)
5

Electrocardiogram [ECG]
•Record of
•Potential fluctuations
•During a cardiac cycle
6

Electrocardiograph
•Recording device
•Recording Machine

7

ECG Paper
•Recorded on  Heat sensitive paper
•Time (Duration) measured on X-axis
•Voltage measured Y-Axis

8

ECG Paper
•ECG paper has 
•Small boxes of  1 mm
2

•Five (5) small squares demarcated by 
•Thick line
9

Horizontal Calibration Line
•Voltage calibration lines
•10 of the small line divisions
•Each one 0.1 mV
•Upward or Downward
•In the standard ECG represent  1 millivolt
10

Horizontal Calibration Line  Voltage
•Positivity  Upward direction
•Negativity Downward direction
11

Y – Axis  Each small square
•Each of small square
•On Y- Axis corresponds to 0.1 mV

12

Vertical Calibration Line
•Time calibration lines


13

Speed of Typical ECG
•25 mm per Second
14

Each 25 mm  Horizontal direction
•25 mm Horizontal direction 1 second
•1 mm  0.04 sec
15

Each 5 mm Segment 
•Indicated by the Dark vertical lines
•Represents  0.20 second
16

0.20 second intervals broken  5
•Broken into 5 smaller intervals
•0.20 / 5  Each 1 mm on X-axis  0.04 sec
•Speed of the ECG Paper  25 mm / sec
•So 1 mm = 0.04 sec
17

X-Axis  Each small 1mm square
•Equal to 0.04 sec
•When speed of the ECG paper is 25 mm / sec
18

Y-Axis  Each small 1mm square
•Equal to 0.1 mV
19

Calibration  Before Recording
•ECG machine
•Calibrated before each recording
•For normal recording

20

Calibration  Before Recording
•Instrument has to be Calibrated to show
•Displacement of  10 mm for 1 mV
•Each 1mm (Y-Axis) correspond to 0.1mV
21

Speed of ECG Paper
•ECG paper can be moved at 2 Speeds
•Depending on type of recording
•Normally a speed of 25mm/sec

22

Speed  25 mm / sec
•Paper moves a distance of
•1500 mm in 1 minute
•25 mm x 60 sec = 1500 mm / minute

23

Speed  50 mm / sec
•Used when Heart rate (60 to 100 bpm)
•Heart rate  High Tachycardia
•Better view of different waves is required

24

Rate of Heartbeat from ECG
•Can be determined
•As the heart rate is the
•Reciprocal of the time interval
•Between two successive heartbeats
25

Calculation of Heart rate from ECG
•1500 / RR interval
•1500 / Small squares
•Between 2 RR interval
26

Calculation of Heart rate from ECG
•1500 / Small squares between RR Interval
•1500 / 23 = 65 beats per minute
27

Calculation of Heart rate from ECG
•1500 / Small squares between RR Interval
•1500 / 23 = 65 beats per minute
28

Calculation of Heart rate from ECG
•Heart rate can be calculated
•When heart beats Regular
•Cannot be used  Irregular beats
•RR or PR interval will vary
29

ECG  Recorded
•From the surface of the body
•Using different electrodes


30

Types of Leads
1.Bipolar leads
2.Unipolar leads
31

ECG Recorded in Unipolar recording
•Using an
•1 Active or Exploring electrode
•1  Indifferent electrode at Zero potential
32

ECG Recorded in Bipolar recording
•Using an
•2 Active or Exploring electrode
33

Bipolar / Standard Limb Leads
•Electrical connections between
•The Patient’s limbs and
•The Electrocardiograph for recording ECGs
34

3 Bipolar / Standard Limb Leads
•Leads record
•Potential difference
•Between  2 limbs

35

“Bipolar” means…
•The electrocardiogram is recorded
•From  Two (2) electrodes
•Located  On different sides of the heart
36

Bipolar / Standard Limb Leads
•Two (2) electrodes
•Located at  The Limbs
37

“Lead” Not Single wire
•Is
•Not a single wire
•Connecting from the body

38

“Lead”  Combination of
•2 wires and their Electrodes
•To make a complete circuit
•Between the body and Electrocardiograph
39

3 Bipolar / Standard Limb Leads
1.Lead I
2.Lead II
3.Lead III
40

Limb Lead I
•Negative terminal of the electrocardiograph
•Connected to the Right arm 
•Positive terminal is connected to the Left arm
41

Limb Lead I
•When the point where
•Right arm connects 
•To the chest is electronegative
•With respect to the point where
•The Left arm connects
42

Limb Lead I  Recoding
•The electrocardiograph records
•Positively
•Above the zero voltage line in the ECG
43

Limb Lead II
•Negative terminal of the electrocardiograph
•Connected to the Right arm
•Positive terminal is connected to the Left leg
44

Limb Lead II
•Right arm 
•Electronegative
•With respect to
•The Left leg
45

Limb Lead II  Recoding
•The electrocardiograph records
•Positively
•Above the zero voltage line in the ECG
46

Limb Lead III
•Negative terminal of the electrocardiograph
•Connected to the Left arm
•Positive terminal is connected to the Left leg
47

Limb Lead III
•Left arm 
•Electronegative
•With respect to
•The Left leg
48

Limb Lead III Recoding
•The electrocardiograph records
•Positively
•Above the zero voltage line in the ECG
49

•The triangle, Called
•Einthoven’s triangle
•Is drawn around the area of the heart
Einthoven’s Triangle
50

•The Two arms (Right & Left Arms)
•The Left leg
•Form  Apices of a triangle
•Surrounding the heart
Einthoven’s Triangle  Illustrates
51

•Represent the points At which
•The Two arms  Connect
•Electrically with the fluids around the heart
2 Apices at Upper part of Triangle
52

•Is the point
•At which
•The Left leg  Connects with the fluids
Lower Apex of Triangle
53

•If the ECGs are recorded simultaneously
•With the three (3) limb leads (I , II, III)
•Bipolar or Standard limb leads (I, II, III)
Einthoven’s Law
54

•The Summation (+) of the potentials recorded
•In Leads I and Lead III
•Will equal the potential in Lead II
Einthoven’s Law
55

•Lead I potential + (Plus)
•Lead III potential
•Equal to  Lead II potential
Einthoven’s Law
56

•If the electrical potentials of
•Any 2 of the 3 bipolar limb electrocardiographic
leads
•Are Known
•At any given instant
Einthoven’s Law Importance
57

•The potential of 3
rd
one
•Can be determined
•By simply summing the first two
Einthoven’s Law Importance
58

•Lead I potential + (Plus)
•Lead III potential
•Equal to  Lead II potential
Einthoven’s Law
59

•That the Positive and Negative signs
•Of the different leads
•Must be observed
•When Making this summation
Note  + / - Signs Must
60

•Lead I = +0.5mV
•Lead III = +0.7mV
•Lead II = +1.2mV
Potential in all 3 Bipolar Limb Leads
61

•Lead I potential +Lead III potential = Lead II potential
• (+ 0.5 mV) + (+0.7mV) = (+1.2mV)
Einthoven’s Law
62

•Holds true at any given instant
•While
•The three (3) “Standard”
•Bipolar ECGs are being recorded
Mathematically Einthoven’s Law
63

Recordings of Bipolar / Standard Limb Leads
•All record
•Positive P waves
•Positive T waves and
•The major portion of the QRS complex
•Is also positive in each ECG

64

Unipolar (V) Leads  9
•9 Unipolar leads
•Records  Potential difference between
•An exploring electrode & An indifferent electrode
65

Unipolar (V) Leads  9
•6  Standard Unipolar Chest Leads
•3  Augmented Unipolar Limb leads
•Total = 9
66

Chest Leads (Precordial leads)
•ECGs are recorded with
•One electrode placed
•On the  Anterior surface of the chest
•Directly over the heart at V
1,V
2,V
3,V
4,V
5 &V
6
67

Chest Leads (Precordial leads)
•V
1 = 4
th
ICS to the Right margin of the Sternum
• V
2 = 4
th
ICS at the Left margin of the Sternum


68

Chest Leads (Precordial leads)
•V
4 = 5
th
ICS Midclavicular line
•V
3 = In between V
2 & V
4
• V
5 = 5
th
ICS in the Anterior axillary line
•V
6 = 5
th
ICS in the Mid axillary line

69

Chest Leads (Precordial leads)
•One electrode placed at  V
1,V
2,V
3,V
4,V
5 &V
6
•This electrode is connected
•To the Positive terminal
•Of the Electrocardiograph [ECG machine]

70

Chest Leads (Precordial leads)
•The Negative electrode  Indifferent electrode
•Is connected through equal electrical resistances
•To the Right arm, Left arm, and Left leg
•All at the same time

71

•With the chest electrode being placed
•Sequentially
•At the 6 points shown in the diagram
6 standard Chest Leads are recorded
72

•One at a time
•From the Anterior chest wall
6 standard Chest Leads are recorded
73

•Known as...
•Leads V1, V2, V3, V4, V5, and V6
Different recordings of 6 Chest leads
74

•Of the cardiac musculature
•Immediately beneath the electrode
•Because
•The heart surfaces are close to the chest wall
Chest leads Records Electrical Potential
75

Unipolar (V) Leads  9
•6  Standard Unipolar Chest Leads
•3  Augmented Unipolar Limb leads
•Total = 9
76

3 Augmented Unipolar Limb Leads
•Unipolar leads
•Records Potential difference between
•An Exploring electrode and Indifferent electrode
77

3 Augmented Unipolar Limb Leads
•Augmented limb leads  Record 
•Potential difference between
•One Limb & the Other 2 Limbs
78

3 Augmented Unipolar Limb Leads
•Two (2) of the limbs are connected
•Through Electrical resistances
•To the Negative terminal of the ECG machine
79

3 Augmented Unipolar Limb Leads
•The Third (3
rd
) limb
•Is connected  To the Positive terminal
•of ECG Machine
80

Positive Terminal is on Right Arm
•The lead is known as the 
• aVR lead
81

Positive Terminal is on  Left Arm
•The lead is known as the 
•aVL lead
82

Positive Terminal is on  Left Leg
•The lead is known as the 
•aVF lead
83

3 Augmented Unipolar Limb Leads
1.aVR 
▫Exploring (+Ve) electrode connected to Right Arm
2.aVL 
▫Exploring (+Ve) electrode connected to Left Arm
3.aVF 
▫Exploring (+Ve) electrode connected to Left Leg

84

Normal recording of Augmented Limb Leads
•All similar to the standard limb leads
•Lead I, II, III recordings
85

Normal recording of Augmented Limb Leads
•Except recording from
•The aVR lead is  Inverted
86

Normal ECG composed of
1.P wave
2.QRS complex
3.T wave
87

Normal ECG composed of
•QRS complex is often
•But not always
•Three 3 separate waves:
•The Q wave, The R wave, and the S wave
88

Waves recorded in ECG  Depend
•On The Pattern of depolarization
•On  Position of the heart
•In  Relation to the recording electrodes
89

Atria Located 
•Posteriorly
90

Ventricles form 
•Base
•Anterior surface
•of the Heart
91

Right Ventricles is 
•Anterolateral 
•To the Left ventricle
92

Recording from aVR  Inverted
•aVR  “Looks at” the cavities of the ventricles
•Atrial depolarization
•Ventricular depolarization
•Ventricular repolarization
•Move away from the exploring (Positive) electrode
93

Recording from aVR  Inverted
•P wave
•QRS complex
•T wave are
•All negative (downward) deflections
94

Recording from aVL,aVF Positive
•aVL and aVF look at the ventricles
•The deflections are
•Therefore
•Predominantly “Positive” or “Biphasic”
95

Chest leads V
1 & V
2
•No  Q-Wave

96

Chest leads V
1 & V
2 QRS complex

•A small upward (Positive )deflection
•because
•Ventricular depolarization first moves across
•The mid portion of the septum
•From left to right toward exploring electrode
97

Large S wave  Negative
•The wave of excitation
•Then moves down the septum
•Into the left ventricle
•Away  From the exploring (Positive) electrode
•Producing a large S wave
98

Wave of Excitation
•Moves 
•Towards  Exploring (Positive) electrode
•Positive deflection
99

Wave of Excitation
•Moves 
•Away from  Exploring (Positive) electrode
•Negative deflection
100

Return to the Isoelectric Line
•Wave of excitation finally moves back
•Along the ventricular wall
•Toward  The electrode
•Producing the return to the isoelectric line
101

ECG:
Waves, Intervals, Segments & Uses
Dr.Viral I. Champaneri, MD
Assistant Professor
Department of Physiology

102

ECG Waves
•Composed of both
•Depolarization waves
•And
•Repolarization waves
103

Repolarization wave
•Halfway repolarization of the same muscle fiber,
•With
•Positivity returning to the outside of the fiber
104

Repolarization wave
•The left electrode is in an area of positivity
•The right electrode is in an area of negativity
•Consequently,
•The recording becomes negative
105

P Wave  Atrial Depolarization
•Occurs 
•Electrical potentials generated when
•The atria depolarize
•At the before
•Contraction of the atria
106

P Wave  Normal duration
•0.1 second
•Calculated from X-Axis 
•Vertical calibration line
107

P Wave  Voltage (mV)
•0.1 to 0.3 milliVolts (mV)
•Calculated from Y-Axis 
•Horizontal calibration line

108

P Wave Upright Wave
•In all the Leads
•Positive wave
109

P Wave  Inverted Wave
•In  aVR
110

P Wave  Inverted Wave
•In Nodal rhythm
•Nodal rhythm 
•Impulses travel in opposite direction
•From AV node towards SA node
111

P Wave  Absent  SA block
•SA node (Sinoatrial node  Pacemaker)
•Does not generate the impulses
•As in  SA Block
112

QRS complex  Beginning of Ventricular contraction
•QRS complex  due to
•Potentials generated
•When the Ventricles depolarize
•Before contraction
113

QRS complex  Due to
•Ventricular depolarization
•Atrial repolarization
114

QRS Complex  Normal duration
•0.08 – 0.1 second
115

Normal Voltage in ECG
•On the manner in which the
•Electrodes are applied To the surface of the body
•How close the electrodes are to the heart
116

QRS Complex Voltage  3 to 4 mV
•1
st
electrode is placed directly over the ventricles
•2
nd
electrode is placed
•Elsewhere on the body remote from the heart
117

QRS Complex Voltage  1.0 to 1.5 mV
•When ECGs are recorded from electrodes
•On the two arms or (Augmented Limb Leads)
•On one arm and one leg (Augmented Limb Leads)
118

QRS Complex Voltage  Calculation
•From
•The top of the R wave
•To
•The bottom of the S wave
119

QRS Complex  Importance
•Helps to determine 
•Electrical axis of the heart
120

Q R S T Waves  Ventricular complex
•Average duration of Q R S T  0.43 seconds
•Q R T  0.08 sec
•Should not exceed  0.1 seconds
121

Q Wave  Cause
•Contraction of
•Muscular part of the interventricular septum
122

Q Wave  Characteristic
•Small
•Negative wave
•Inconspicuous displacement
123

Q Wave  Not found
•Reptiles and Amphibians ( e.g. Snakes & Frogs)
•Do NOT possess  Interventricular septum

124

Q Wave Congenital patency of septum
•Q wave Absent
•VSD Ventricular reptum defect
•Infants having 
•Congenital patency of interventricular septum
125

Q Wave  Prominent
•Old Myocardial Infarction (MI)
126

R Wave  Tallest amplitude
•Constant
•Conspicuous
•First positive deflection
•During ventricular depolarization
127

S Wave  Downward deflection
•Constant but
•Inconspicuous
128

In Bipolar Limb Lead I 
•R wave  Right ventricle
•S wave  Left ventricle


129

In Bipolar Limb Lead III 
•R wave  Left ventricle
•S wave  Right ventricle


130

Bundle Branch Heart Block
•Duration of the R and S wave 
•Prolonged beyond 0.1 second
•Amplitude (mV) varies

131

T wave  Cause
•Caused by the action current
•Due to the contraction of
•The basal parts of the ventricles
132

T Wave  Atrial Repolarization
•Atria repolarize
•About 0.15 to 0.20 second
•After termination of the P wave
133

T Wave  Atrial Repolarization
•Which is also approximately
•When the QRS complex
•Is being recorded in the ECG
134

T Wave  Atrial Repolarization
•Atrial T wave
•Is usually obscured by the
•Much larger QRS complex
135

T Wave  Ventricular Repolarization
•Ventricular Repolarization
•Process normally occurs ventricular muscles
•After 0.25 to 0.30 seconds after depolarization

136

Ventricular Repolarization T wave  Duration
•0.15 seconds
137

•Ventricular muscle begins to repolarize
•In some fibers about 0.20 second after
•The beginning of the depolarization wave (QRS)
T wave in normal ECG is
Prolonged wave
138

•But in many other fibers it takes
•As long as 0.35 second
•The process of ventricular repolarization extends
•Over a long period  About 0.15 seconds
T wave in normal ECG is
Prolonged wave
139

•Because of
•Prolonged length of the T wave
Voltage of T wave < Voltage of QRS
140

T wave  Normally Positive
•The apex of the heart repolarize
•More earlier than the base of the heart
141

T wave Inverted III
•In Lead III  Normal
•Without apparent reasons
142

T wave  Significance
•Young adults  Prominent
•Old age  Flattened
•Exercise Increases the amplitude in health heart
143

T wave  Altered
•Stimulation of the Vagus (X
th
- CN)
•By Digitalis & Poisons
•Anoxia  Constriction of coronary arteries
144

T wave  Inverted  Other Leads
•Abnormal Seen in
1.Myocardial Ischaemia
2.Myocardial Infarction (MI)
3.Ventricular Hypertrophy
145

T wave  Lead I & II
•Abnormalities
•Size
•Shape
•Duration
•Direction
•Reaction to exercise
146
Prognostic
Significance
Myocardial damage
Cardiac hypoxia

U wave  Seen after T wave
•Inconstant finding
•May be due to Ventricular myocytes
•With long action potentials
147

U waveRepolarization of
1.Septum of ventricles (Interventricular)
2.Papillary muscle
148

U wave 
•However,
•The contributions to this segment
•Are still undetermined
149

ECG Waves
Duration
(second)
Voltage
(mV)
P wave 0.1 0.1 to 0.3
QRS Complex 0.08 – 0.1
3 to 4 mV
1.0 to 1.5
(Augmented
leads)
Ventricular
T wave
0.2 – 0.3 -
150
Duration & Voltage of ECG Waves

ECG Intervals
1.P – P Interval
2.R – R Interval
3.P – Q or P – R interval
4.QRS duraion
5.Q-T interval
6.S-T interval
151

R – R Interval  How to Measure
•Interval between
•2 successive R Waves
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R – R Interval  Significance
•If the R – R interval in next successive stage
•Same  Indicates 
•Ventricles depolarizing rhythmically
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P – P Interval  How to Measure
•Interval between
•2 successive P Waves

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P – P Interval  Significance
•If the P – P interval in next successive stage
•Equal 
•Rhythmical depolarization of the atrium

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Short notes: 4 Marks
•Significance of P-R interval in ECG.
•Name where P-R interval prolonged

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P-Q or P-R Interval  How to Measure
•Measured
•From  Beginning of P wave
•To  Beginning of QRS complex
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P-Q or P-R Interval 
•Often this interval is called  PR interval
•The Q wave is likely to be absent
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P-Q or P-R Interval  Significance
•Interval between
•Beginning of electrical excitation of the Atria &
•Beginning of excitation of the Ventricles
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P-Q or P-R Interval  Significance
•Atrioventricular conduction (AV conduction)
•Indicates time for Atrial depolarization
•Conduction through the AV node
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P-Q or P-R Interval  Significance
•Conduction time of the impulse
•From the SA node
•To the Ventricles
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P-Q or P-R Interval  Variable
•Variable P – R interval 
•Successive stages of
•Atrioventricular Dissociation
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P-Q or P-R Interval  Duration
•@ Heart rate  70 beats / minute
•Range : 0.12 – 0.20 Seconds (Ganong)
•Average: 0.18 seconds (Ganong)
•Guyton : 0.16 Seconds
163

P-Q or P-R Interval  Shortens
•As Heart rate  Increases Tachycardia
•From  average of 0.18 s at a rate of 70 beats/min
•To  0.14 seconds at a rate of 130 beats/min
164

P-Q or P-R Interval  Increases in
•Wenckebach Phenomenon
•Form of  Incomplete heart block
•P – R interval gradually prolonged
•Until  Ventricular beat is missed
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P-Q/P-R Interval  Very Short WPW
•Wolff – Parkinson-White (WPW) syndrome
•Additional Muscular or Nodal tissue connection
•Between Atria & Ventricle Bundle of Kent
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P – R IntervalWPW Syndrome
•Bundle of Kent 
•Conducts excitation impulses
•Faster to one ventricles than
•Slow conducting AV- node (0.1 second delay)
167

WPW Syndrome
•Wolff – Parkinson-White (WPW) syndrome
•Shorter PR Interval
•Prolonged QRS complex
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Wolf -Parkinson-White Syndrome
•Bundle of Kent
•Shorter PR or PQ Interval
•Prolonged QRS complex
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QRS Duration  Normal
•Range : 0.08 – 0.1 Seconds
170

QRS DurationHow to measure
•Beginning of the Q wave
•To
•End of S wave
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QRS Duration  Significance
•Measures 
•Total ventricular depolarization time
172

Q – T IntervalHow to Measure
•Measured
•From  Beginning of Q wave or
•From Beginning of R wave (If Q-wave Absent)
•To  End of T wave
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Q – T Interval  Significance
•Ventricular Action potential
•Ventricular electrial events
•Depolarization & Repolarizaiton

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Q – T Interval  Significance
•Measures 
•The ventricular total systolic time

175

Q – T Interval  Duration
•Range : 0.40 – 0.43 Seconds (Ganong)
•Average: 0.40 seconds (Ganong)
•Guyton : 0.35 Seconds
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Q – T Interval  Reduced
•Can be lower  0.35
•Depending on the heart rate

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Q – T Interval  Altered
•Drug  Quinidine
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S – T Interval  How to Measure
•ST interval = QT Interval – QRS duration
•ST interval = 0.40 – 0. 08
•ST Interval = 0.32 seconds
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S – T Interval  Significance
•Plateau portion of the
•Ventricular Action potential
180

T – P Interval  How to measure
•End of T wave
•To
•Beginning of P wave
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T – P Interval  Significance
•Alteration of this interval
•Indicates  Alteration of the heart rate
182

T – P Interval  Measures
•The diastolic period of the heart
183

ECG Segments
1.S-T segment
2.P-Q segment

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S – T Segment  How to Measure
•Segment Between 
•End of S wave
•Beginning of T wave
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S – T Segment  Isoelectric line
•Present on  Isoelectric line
•Ventricles completely depolarised
•No potential difference recorded in S-T segment
186

S – T Segment  Duration
•Average: 0.32 seconds

187

S – T Segment  Depression
•Ischaemia Ventricular muscle
•Causes Depression of ST segment

188

S – T Segment  Elevation
•Acute Myocardial Infarction  Acute MI
189

S – T Segment
•Why ST segment elevation or depression occurs..?
190

Myocardial Ischaemia & Infarction
•Ventricular muscles
•Not  Completely depolarized 
•Partly depolarized
•Potential difference is recorded
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Myocardial Ischaemia & Infarction
•Potential difference 
•Shift the ST segment
•From the Isoelectric line
•ST depression Ischaemia
•ST elevation Infarction
192

S – T Depression  Myocardial Ischaemia
•ST depression Ischaemia

193

S – T Elevation  Myocardial Infarction
•ST elevation Infarction


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ECG Interval
Duration
(seconds)
P – Q or P – R
Guyton  0.16
Ganong  0.12 to 0.20
QRS Duration 0.08 – 0.1
Q – T
Guyton  0.40 to 0.43
Ganong  0.35
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ECG Intervals
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