Erythropoietin

https://www.facebook.com/profile.php?id=100007500842607

1. SHREE MEDICAL AND TECHNICAL COLLEGE
BHARATPUR -12, GONDRANG
Presentation on Erythropoietin
PRESENTED BY:
SANJAY KUMAR YADAV
ROLL NO.: 22 (5
th
sem.)
1/18/2020 0sanjay k. yadav

2. INTRODUCTION
Erythropoietin is a Hormone.
Also called Epo.
Produced by kidney.
By which stimulation of red-bone marrow to
produce erythrocytes ( RBCs ).
RBCs transport oxygen throughout the body.
Finally , prevents from the anemia, hypoxia etc.
1/18/2020 1sanjay k. yadav

3. REGULATION
1/18/2020 2sanjay k. yadav

4. DRUGS
Epodrugs are used for treatment of
chemotherapy-induced anemia,
Anemia is common side effect occuringdue to
chemotheraphyof ESRD, cancer and HIV.
Forms of Eposuch as epoetinalfa, epoetinbeta,
epoetinomega, epoetindelta, derbepoetinalfa.
1/18/2020 3sanjay k. yadav

5. DOSES
ANEMIA ASSOCIATED WITH CKD:
----Adult: Initial dose: 50 to 100 units/kg IV or subcutaneously 3
times a week
----Pediatric (1 Month to 16 Years): Initial dose: 50 units/kg IV or
subcutaneously 3 times a week
Conditions:
----If hemoglobin increases by more than 1 g/dLin 2 weeks, reduce dose
by 25%
----If hemoglobin has not increased by more than 1 g/dLafter 4 weeks
of therapy, increase dose by 25%.
1/18/2020 4sanjay k. yadav

6. Storage conditions: -Protect from light.
-Store at 2 to 8C. -Do not freeze.
Other conditions:
-Do not dilute.
-Do not shake.
-Allow this drug to reach room temperature before
injecting.
-Do not use preservative-free vials.
1/18/2020 5sanjay k. yadav

7. 1/18/2020 6sanjay k. yadav