Ethics in Medicine | Jindal Chest clinic

JindalChestClinic 72 views 79 slides Jul 05, 2024
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About This Presentation

This presentation explores the ethical principles and dilemmas faced in the medical field.


Slide Content

Ethics in Medicine
•Ethics–Greekterm“ethikos”(i.e.customary).
•Moralobligationswhichgovernactionsinbiologicalsciences–medicine,
environmentalandphilosophicalsciences.
Equity(i.e.Fairnessprinciplesofjusticeusedtocorrectorsupplementthelaw)
constitutesthebasisofallethicsinthemodernsociety.
Partlysocialandprofessionalguidelines
Partlylegal(Caselaw/Statutelaw)

Medico-Legal Issues
MedicalJurisprudence-ScienceorPhilosophyofLaw(relatedtoMedicine)
MedicalNegligence
•Lackofpropercareandattention
•Culpablecarelessness(Culpable-deservingblame)
MedicalEthics
•Professionalpractice(clinicalindications/Commerce)
•ResearchandTechnology
•Publications

Medical Negligence
•Disease-diagnosis/Tests
•MedicalExpertiseDisease–information
•Standardsofcare
•Treatment–Drugs/Interventions
•EmergencyManagement
•Costs/Referrals
•Complications
•ViolationofActs

How to Avoid Problems?
1.Follow standard procedures –in place.
2.Consult others / seniors
3.Communicate well with patients / attendants
4.Good record-keeping
5.Adequacy of care (as per standards / Guidelines in place)

Why should doctors learn about ethics?
•Unusualinfluenceoverpatients’lives
•Balancetherightsandinterestsofsocietywiththatofpatients
•Civilrightsmovement
•Avoidethicalconflictsandthinkthroughethicaldilemmas
•Avoidjudicialoversightwithlegalandregulatorysystems–Personaland
Institutional

BASIC ETHICAL PRINCIPLES
•Autonomy–anindividual’srighttoself-determination
•Beneficence–todogood
•Nonmaleficence-donoharm
•DistributiveJustice-thejustandequitableprovisionoffinitehealth
careresources

Evolution of Medical Ethics
Hippocratic tradition
Philosophical inquiries
(Principle based moral theories)
Antiprinciplism
(Competing moral theories)
Crisis
(Conceptual conflicts –Skepticism of morality)
(Pellegrino, 1993)

Beneficence
•HasrootsintheHippocraticdoctrineoffosteringthepatient’swell-being
•Moralobligationtopromotegoodnessorbenefittothepatientandfamily,
toprovidecarethatmaintainsorimproveshealth,reducesdisability,and
alleviatesphysical,andexistentialpainandsuffering.
•Littlequarrelregardingnobilityofthesegoals
•Fewconflictsnevertheless

Nonmaleficence
•EmbodiedintheHippocraticdictumprimumnonnocere(first,dono
harm)
•Typicallyisseenasamorestrictrequirementthanbeneficence
•Disagreementabouttheproperbalancebetweenbeneficenceand
nonmaleficence

Ethics Determinants
•Cultural-social,religiousandethnicvaluesandcustoms
•Economicandcommercialissues
•Legalsystem
•Internationalcodes
•Politicalpower
•Individualbiases,beliefsandrights

Autonomy
•Patientsautonomyandtherighttoself-determinationarewellestablished
ethicalprinciplesandlegalrightsinmedicine.
•Manypatientsareincapableofmakingtheirowndecisions,oftencausing
ambiguityanduncertainty,whichcanleadtoconflictsamonghealthcare
providersandfamilies.

Distributive Justice
•Thisis,perhapsthemostdifficulttointerpretandimplement
•Personaljustice:physiciansmusttreateachandeverypatientwithrespect
andfairness
•Socialjustice:whichdovetailswithmedicalfutility;inaworldwithlimited
resources,ineffectivetreatmentsforaparticularindividualmaywaste
resourcesbetterspentonappropriatetherapiesforothers

Autonomy –Issues & Concepts
•Capacity
•Informed consent
•Surrogate decision making
•The best argument
•Paternalism
•Resuscitation status

Capacity
Presumptionthatadultshavetheabilitytomakedecisionsforthemselves
andabletoparticipateintheprocessofinformedconsent
“Incompetent”individuals
•Children
•Prisoners
•Mentallychallenged
•Dependents

Informed consent
*Disclosure*Understanding*Voluntariness
Exceptions
•Lifethreateningemergenciesinwhichdelaywillresultinharmtothe
patient
•Patientwaivestherighttoinformedconsent
Informedrefusal
•ImportantinICUswhenconsideringwithdrawingorwithholdinglife
support.

Surrogate Decision Making
•Patientlosescapacity
•Mostcommonlyafamilymember:“surrogate”or“proxy”forthe
patient
•Itisthesurrogate’sresponsibilitytorepresentthepersonalvaluesof
thepatient
•Difficultieswhenvaluesetisnotwelldefinedordisagreementamong
familymembers

Best Interest Argument
•Whenapatient’swishesareunknownbythefamilymembersandthereisno
designatedproxyforhealthcaredecisions,the“bestinterest”standard
prevails
•Doctorsaremorallyobligatedtooverruleasurrogateifthereisclear
evidencethatdecisionsarebasedonsurrogate’spersonalvaluesthanthe
patient.

Advanced directives…
•NowincreasinglyusedforEnd-of-Life&Criticalcare
•Enableapatienttomaintainadegreeofcontroloverhisorherlife,even
afterthecapacitytomakedecisionsislost.
•ThecardcarriedbymanyJehovah’sWitnesses,detailingtheirrefusalto
acceptbloodorbloodproducts.
•Legalstatus:ChangingandisnowbecomingpartofUKlawforthefirst
time.NotyetacceptedinIndianLaw.

Medical Ethics: Domains
1.Clinicalpractice
2.MedicalResearch-Human
-Animal
-Laboratory
3.Epidemiological
4.Economicalissues
5.Medicalteaching
6.Biotechnology
7.Management

CLINICAL PRACICE
Physiciansarelikekings;theybrooknocontradiction
JohnWebster,1580-1625

CLINICAL PRACTICE ISSUES
1.End-ofLifeCare&Dignityofdeath:
PalliativeCareand“Allowingtodie”
(Euthanasia–“assisted”and“mercykilling”)
2.Organtransplantation
Live-donor
Cadaver–Brainstemdeath
3.Sexselection–Abortion
4.AssistedReproduction:
Ovumdonation
Surrogatemotherhood…
5.GeneticEngineering
6.Cloning

END-OF-LIFE (TERMINAL) CARE

Death
Time
Health Status
TRAJECTORIES of Death
1. Sudden Death 2. Progressive Illness
Death
Time
Health Status

Death
Time
Decline
Health Status
3. Slow decline and Crises

Problems of the Terminally Sick Patients
1.Fearofdeath
2.Symptomsandsuffering
3.Socialisolation
4.Financialpressures
5.Medicaldisinterest
6.Nihilisticapproaches
7.Denialofdeath

Important Issues for Doctors
•Palliativecare–reliefofsymptomsvs.Lifeprolongingtreatments
•Hospiceversushospitalization
•Tellingtheobvious
•Managementinthelasthoursofliving
•Patient’sobligations:Family,financial,social,spiritual,religious
•Afterdeathhandling
•Bereavement

Acts and Omissions
•Treatmentwithheld/withdrawnevenifallowsdiseaseprogressiontonatural
death
•Importantdistinctionbetweenallowingthepatienttodieanaturaldeath
(allowingillnessprogressionnormally)andactivelydoingit(intentional
killing)
•Decisionbasedoninabilityofpatienttobenefitfromthetreatment
(Read“GuidelinesforWithdrawalofTreatmentofIrreversiblyCriticallyIll
patientsonAssistedRespiratorySupports”www.pgimer.nic.in)

Euthanasia and physician –assisted
suicide
•Activeeuthanasiaisillegal-TheNetherlandsandBelgiumpermit
voluntaryactiveeuthanasiabylethalinjections
•Physician-assistedsuicideislegalinsomecountriesandstatesofNorth
America,suchasSwitzerlandandOregon
•IndianCourtsdonotaccepttheconcepts

Do not resuscitate (DNR) orders
•CPRishighlyeffectiveinventricularfibrillation
•Notsuccessfulasaroutinetoalldyingpatients(criticallyillpatientswith
multiorganfailureoroverwhelmingsepsis)
•DNRordershasleadtoconflictb/wdoctorsandpatient’sfamilies
•NosanctionforDNRinIndia
•Goodcommunication,whyCPRwillbecommencedresolvesmanysuch
issues.CPRmaynotbewiseornecessaryinknown,end-stagediseasein
theabsenceofareversiblefactor

Rule of double effect (RDE)
•Interminalcare,thereisanobligationtomaximizethepatient’scomfort
andminimizethepain&distress
•Drugssuchasopioidsandbenzodiazepineareoftenrequiredmore
liberally
•Theharmfuleffectsofdrugsmayappeartohastenapatient’sdeath(i.e.
doubleeffect)
•TheUSSupremeCourthasgivenRDElegitimacy

Medical Commerce
“Wecannotexpecttoseemuchactionuntilenoughpolicymakerslosetheir
fascinationwiththeviewthathospitalsarebasicallybusinesses”.
ArnolRelman,NEJM1985
Ahospitalisbothalikeandfundamentallydifferentfromafactory,public
schoolorcorporateheadquarters.
ChaslesRosenberg,1987

A CODE OF MEDICAL ETHICS
ForinformationoftheRegisteredMedicalPractitionersonthePunjabMedical
Register
PartI:AcodeofMedicalEthics
GeneralAdvice
PartII:Warningnotice
Somemattersofforensicimportance

Health-Research: Ethical Issues
1.Subversionofresearch
Entrepreneurship
Conflictsofinterest
Growingalliance
2.Dangers:Unknownrisksvspromiseofbenefits
3.Patentprotection
4.Citation&Publication

BIOETHICS in Health-Research
•Restrictive/prohibitivetogrowth?
WHYNEEDED?
•Preventingmisguidance
•Warningfuturemisuse
•Protectingthepublicinterest
Bioethicspromoteadisciplinedapproach

Specific Areas of Concern
1.ObjectivesofResearch:Methodology&Safety;Costsofinvestigations;
Sponsorships
2.AnimalResearch:Numbers,Up-keep,Animalrights
3.Newdrugdevelopment-DNAandgenetictechnology
4.Geneticallymodifiedfoodsandplantbaseddrugs
5.Useoflivingcells;cell-lines
6.Assistedreproductiontechniques
7.Chimeratechnology
8.Biobanks,humangenepatents,stemcellresearch,humancloning
9.Bioinformaticsandbiologicalweapons
10.Plagiarism&Falseclaims

ICMR Guidelines -I
•Essentiality
•Voluntariness–informedconsentandcommunityagreement
•Non-exploitation
•Privacyandconfidentiality
•Precautionsandriskminimization

ICMR Guidelines -II
•Professionalcompetence
•Accountabilityandtransparency
•Maximizationofthepublicinterestandofdistributivejustice
•Institutionalarrangements
•Publicdomain
•Totalityofresponsibility
•Compliance

Publication & Authorship
For“intellectualworks”:Papers,Projectreports,images,electronic(etc.)
I.CitationandCopy-rightissues
II.Plagiarism(Passoffanotherperson’sthoughts,writingsasone’sown).
III.Authorshipissues:Itinvolves-
i.Accountability:Intellectual,Professional,Moral,Social,Legal
ii.ResponsibilityforContentsErrors&Omissions

Fundamental principals for authorship
Allthree
1.Substantial,intellectualcontribution
2.Participationinwriting,reviewingofthedraftsandapprovalofthefinal
version
3.Precisecontributionshouldbeidentifiableandjustifiable.
Authorshipisnotacharity–shouldbeearnedasabove.

What is intellectual contribution?
1.Conceptualization
2.Performanceofexperimentsanddatacollection
3.Conductinganalysisandinterpretingdata
4.Reviewingliterature,assessingaccuracy&relevancy,writingsignificant
partofpaper
5.Involvementindatacollection,verification,supervisionandguidance,
analysisandwriting(throughoutorformostofthestudyperiod).

Framing Ethics: Difficult Issues
•ImperviousvsResponsive
•Fusionoftheoryandpractice
•Conceptualframeworkof
Rightorwrong
Goodorbad
Conflictsofmorality
Otherconflicts:Personal/Social/Cultural/Legal/Professional/
Commercial/Political

Ethical Management Guidelines for
Leaders of Academic Medical Centres
•Threats(fiscal/others)toAHCs
•Powerconcentrationinleaders–
“Ethicalconceptsofprofessionalismandjusticerequired”
“Voluntarycooperationofallstakeholders”
“Fosteringfinancialviability”
Chervenaketal,AcadMed2002

Value system vs. Decision making
Itisnotonlythatvaluesystemsinevitablycreepintobiasdecision-making,
althoughtheydo.Itisratherthatpolicymakinglogicallyrequiresasystem
ofvalues.Inlargepartthosevaluesaredeterminedbyculture.
RobertVeatch

Handling Ethical Concerns
New discovery / vision
Social / Political /
Professionalcriticism / concerns
Commissions
Guidelines
Laws / Legislation

Part I
A Code of Medical Ethics (Pb. Med. Council)
1.DignityofProfessionofmedicinemaintainedonalloccasions…followingandsimilar
practicesavoided.
a.Solicitingpvt.Practice…advts.
b.Derivingpecuniaryprofitfromsaleofanysecretremedy
c.Shareinprofits
d.Publishingorsanctioningpublicationofreportsofcases,operations,lettersofthanks…
e.Coveringpersonsnotregd.UnderMedicalActs
f.Keepinganopenshop…
g.Talkingtoorassociationwiththeprofessionunconnected…
h.Agreeingtotreatpatientontheterms“nocurenopayment”basis
i.Givingcertificatesundertheirownnamestomanufacturersofsecretremedies.

Not Necessarily a Right to Authorship 1
•Mereprovisionoffunds,facilitiesoradministrativesupports.
•Mereparticipationindatacollection.
•Workdonebyanemployeeincourseofhis/heremploymentfora
specificpurpose.
•BeingHeadofaDepartment,doesnotqualitytobeauthor.Scientific
contributionisrequiredforauthorship.
•Authorshipdistributionshouldnotbeacharity–itshouldbeearned.
•Preservationofrawdataistheresponsibilityoftheprimaryauthorinthe
department.

Terminal sedation
•TheUSSupremeCourthassanctionedthepracticeofterminalsedation,in
whichthepatientsarerenderedcomatoseandthenmayhavenutritionand
hydrationwithdrawn
•Thoughtheissueiscontentious,theCourtsallowthispracticeifbasedon
informedconsent
•NosuchsanctioninIndia.

Not Necessarily a Right to Authorship 2
Laboratorydata
Routinediagnosticortreatmentinvestigationsinalaboratoryforpatients,
unless:
i,thetestsarecarriedoutforpurposeofthestudy;
ii,asignificantlaboratorydataisbeinganalysedandreported;
iii,thelaboratorydataconstitutesorformsthesubjectofthestudy;
iv,Multiplelaboratorydatafromasinglelaboratoryaretakenandhighlighted;
v,Evensingledata,highlightedincasereport.

Not Necessarily a Right to Authorship 3
Clinicaldata:Routineregistrationofapatient/sinanOPD/Clinic/Warddoes
notconstitutetherighttoauthorship,unless:
i,theworkisbasedononeormoreofthesepatientsorfromthematerialfrom
thesepatients,includingthestoredsamples.
ii,astudyisbeingdonewithreferencetoaclinicalissue(eg.onclinical
patterns,therapy,prognosisandnaturalhistory).

Order of Authorship
•Theleadauthorisgenerallythepersonwhotooktheleadandcontributed
maximally.
•Thesubsequentorderdoesusuallynotspeakoftherespectivecontribution
ofindividualauthors.Thiscouldbeeitheralphabeticalinorderoras
agreeduponbyalltheco-authors.
•Authorsshouldspecifyintheirmanuscriptadescriptionofthe
contributionsofeachauthor.Thisshouldatleastbeidentifiableand
justifiable.

Multi-centre Group and collaborative studies
•Thegroupshouldidentifytheindividual/swhoacceptdirectresponsibilityforthe
manuscript.Theseindividualsshouldfullymeetthethreeprinciplecriteriadefined
earlier.
•Theissueofauthorshipshouldbefranklydiscussedveryearlyinthecourseofthe
workandamutualdecisionshouldbemadeinwriting.
•Thefirstortheseniorauthorshouldgenerallycommunicatewiththejournal-editor
andothersrelatedtothepublication.He/shewilltakealltheresponsibilityasthe
primaryauthor.
Incasethefirstauthorisastudentinthedepartment,thecorrespondingauthorcouldbe
theleaderofthegroupperformingthestudy.
•Thefirstorthecorrespondingauthorshouldbeabletospeakonanddefendthe
paper.

A CODE OF MEDICAL ETHICS
•Shouldnotmeetinconsultationwithnon-registeredpractitioners
•Observepunctualityinconsultation
•Announcingresultofconsultation
•Differencesofopinionshouldnotbedivulgedunnecessarily,but..
•Attendanceshouldceasewhenconsultationisconcluded
•Shouldscrupulouslyavoidinterferencewithorremarksuponthe
treatmentordiagnosis
•Communicatetotherequestingpractitioner.

Justifiedinrefusingtocontinueattendanceoncases
a.Anotherpractitionerinattendance
b.Otherremedies(thanhis)beingused
c.Hisremediesrefused
d.Whereillnessisanimposture
e.Patientpersistsinabuseofopium,alcohol,chloraletc.
f.Subsequentchangeofmind…
Heisnotinanywayboundtogiveupacasebecausehecannot
cureitsolongasthepatientdesirehisservices.

Disputes & Plagiarism
Disputesoverauthorship&otherissuesshouldbebestsettledatthelocallevel
bytheauthorsthemselvesorwiththehelpofthedepartmenthead.
Iflocaleffortsfail,theDirector/Dean/IRBoftheInstituteshouldbeinformed.
Itdoesnogoodbydirectlywritingtothejournal’soffice/editor.
ComplaintsentdirectlytoanEditorofajournallowersthereputationofthe
institution.ThepersonshouldconsulttheDean/Directorbeforewriting
totheEditor.

Preservepatient’ssecrets.Notboundtoanswertopolicemen,solicitors,
vakils…;onlyattheexpressdiscretionofjudgeorMagistratespresiding
inaCourtofLaw.
NotvolunteertogiveevidenceinaCourtofLawagainsthispatient.Should
notappearsubpoena.

Ethical Practices and National
Ethics-Guidelines / Legislation
USA:NationalBioethicsCommission
India:IndianCouncilofMedResearch
Pakistan:LahoreStudy(Humayunetal2008)Inadequateinhospitals
Iran:Structuredapproachtoidentify,analyseandresolveethicalissues–
Nationalguidelines(Zahedi2008)

Brazilian Experience
Threedifferentcommitteesinhospitals:
1.MedicalEthicsCommittee:Toevaluateprofessionalconflicts
2.ResearchEthicsCommittee
3.ClinicalBioethicsCommittee/Rounds
i.Provideconsultancyonethicalquestions
ii.Suggestinstitutionalguidelines
iii.Transdisciplinaryperspective
Goldimetal2008

Professional Domains
Knowing(Education&Research)
Doing(Practice)
Helping(Management)
Thesearethethree‘socialvalues’inarecognizedconceptofanyprofession.
Meston,1981

National Bioethics Commission (US)
1.Handlingdifferences–Worldview
•Politicalorientationanddiscipline
•Dignityofdifference
•Understandingthanagreement
2.Experimentingwith‘prophetic’bioethics
•Critiqueofmodernmedicine
•Alternativeto“regulatorybioethics”(compromise-seeking)

Ethics of questionnaire-based research
“Itdoesn'tcostanythingjusttoask,doesit?”
•Balanceofbenefitsvsharms/time
•Harm–Creating/reinforcinganxietyaboutlifethreateningillnesses;level
ofcare;legalissues.Harmstoparticipatingprofessionals.
Evansetal,JMedEthics2002

Public Policy Formulation
Public Policy leaders
N.G.Os.
Decision makers
Public “scientific literacy” is poor –short of acceptable criteria (only 7% in
American adults –1979)
•Attitudes towards biotechnology ?
•Knowledge –attitude nexus
(Miller 1985; Bastels 1996;
Althaus 1998; Sturgis 2005)

Patent Protection
•Intellectualpropertyrights-Trademark/copyrights
•RightofresearchervsSocietalissues
•Useofthepast“unpatented”knowledgeandwisdom
•Hidinginformation
•Depriving“knowntreatments”-Unethicalculprit

Patent as Unethical Culprit
•CreationofWesternresearch
•Keepingpriceshigh
•Deprivingtheglobalpoor
•Creatingasocialdivideandimbalance
•Unitingfutureresearchanddevelopment

Special Ethical Considerations
MedicalFutility
•Thereisgeneralagreementthatphysiciansnevershouldunilaterallymake
decisionsaboutfutilitywithoutexplainingtothepatientandfamily.
•Thetrendinfutilitycasesisthatwhilecourtdidnotpermitlifesupportlimit
prospectivelyonappealfromdoctors,theytendtodefenddecisionstolimit
lifesustainingtherapywhenmadewithinacceptableprofessionalstandards

Drawbacks in the current strategies
•Thedominanceofautonomyoverthatofbeneficenceoftenleadsto
inappropriatetreatment
•Thedoctoroftenfindhimselfinmoraldilemmawithoutadequatelegalsafe
guardagainstmisinformeddecisionbyfamilies
•Inthispartoftheworldproblemsarecompoundedbytheneedtoration
recoursesandmoralobligationtoprotectfamiliesfromfinancialruin
•Societalpressurealsoerodetheselfesteem

The Indian Scenario
•InIndialegalopinionandlegalizationrelatingtocriticalcareisscarce
•Thereisnoclearlystatedlegalopinionregardingdiscontinuationoflife
supportsystemeveninbraindeadpatients
•InIndiaArticle21providestherighttolife.Howevertheconceptof
autonomyisstillweak

The Indian Scenario…
•TherehavebeenapaucityofcasesdealtwithbyIndiancourtsinthematter
ofendoflifecare
•IntheP-RathinamVSUnionofIndia1994.Thesupremecourtconceded
thatinthecaseofterminalillnessattemptstohastendeathmaybeviewed
asanaccelerationofdyingprocessalreadystarted
•Thecourtacknowledgedthat“apersoncannotbeforcedtoenjoytheright
tolifetohisdetriment,disadvantageordislike”

The Indian Scenario…
•InthecaseofGianKaurvsStateofPunjabthejudgmentdisallowsthe
conceptofeuthanasia
•InIndiathepredominantfactorimpactsdecisionmakingistheunbearable
financialburdenthatitentails

Science or Philosophy of Medical
Jurisprudence Law (related to Medicine)
MedicalNegligence
Lackofpropercareandattention
Culpablecarelessness
(Culpable-deservingblame)
MedicalEthics
• Professionalpractice(clinicalindications/Commerce)
• ResearchandTechnology
• Publications

Principles : Fundamental
•Autonomy(selfrule)
•Justice(Loveofothers)
•Non-maleficence(Lovinglife,donoharm)
•Beneficence(Lovinggood)
Macer1998

•Ethics–Greekterm“ethikos”,
Meaningcustomary,ornature,isthestudyofstandardsofconductand
moraljudgment.
•Systemorcodeofmoralsofaparticularperson,religion,group,or
profession.(Webster,1980)
“Medicalethicsisspecificallyconcernedwithmoralprinciplesand
decisionsinthecontextofmedicalpractice,policyandresearch”

EQUITY
•Fairness
•Principlesofjusticeusedtocorrectorsupplementthelaw.
Equityconstitutesthebasisofallethicsinthemodernsociety.

Positive rights vs. Negative rights
•“negativeright”torefuse:basedonautonomy
andinformedconsent,constitutionalrightsof
privacy,libertyandcommonlawagainst
battery.
•“positiveright”todemandtreatmentlimited
bythephysician’sclinicaljudgmentandhas
nofoundationsinbiomedicalethicsorinlaw.

Whatdoesethicalviolationbydoctorsdo?
–Damagethereputationoftheprofessionandtheperson
–Erodestrustondoctors
–Interferewithpeopleseekingtherapy
–Invitejudicialoversightwithlegalandregulatorysystems–Personal
andInstitutional

HIPPOCRATIC ETHICS
•OathAscetic(self-discipline)philosophy
•Obligationsof
Beneficence(helpful)
Nonmaleficence(official)
Confidentiality
•Prohibitionagainsteuthanasia,abortion,surgery,sexualrelationswithpt.
•“Pure”life–ofvirtue
Lateradditions:rulesregardingdress,gossip,Reputation,cleanliness,truth-telling,
education,Consultationsetc.Emphasisonduty,comparison,loveandfriendship