everything to know about viral infection & influenza

Influenza virus infection transmits through air borne route as well as through contaminated hands

1. The virus infection Dr. Fajar Bahari

2. Morphology Size Viruses are much smaller than cells, ranging from 20 to 400 nanometers in size, while cells range from 10 micrometers to 18 centimeters . For example , viruses are about 2,000 times smaller than a grain of sand and 100 to 1,000 times smaller than human cells

3. The nucleic acid  HUMAN DNA VIRUS 

4. The morphology

5. replication

6. The influenza Dr. Fajar Bahari

7. Influenza virus replication More or Less similar like any other viruses

8. morphology Shape : The influenza virus particle is typically spherical with a diameter of about 80-120 mm but pleomorphism is common. Filamentous forms upto several micrometers in length and readily visible under the dark ground microscope are frequent seen in freshly isolated strains. Symmetry :The virus is core consists of ribonucleoprotien in helical symmetry. The nucleoprotein (NP) associates with the viral RNA to form a ribonucleoprotein (RNP) which is a structure of 9 mm in diameter that assumes a helical configuration and forms the viral nucleocapsid Type A and B influenza virus consist of 8 pieces of segmented RNA (while type C influenza virus contains 7 segments), which encode for 11 proteins (HA, NA, NP, M1, M2, NS1, NEP, PA, PB1, PB1, PB2

9. types Influenza virus A: They are the causative agent for all flu pandemics and are known to infect humans other mammals and birds. Influenza A virus are further classified into sub types based on the properties of their major membrane glycoproteins; Haemagglutinin and Neuraminidase. Till now, 15 HA (H1-H15) sub types and 9 NA1 (N1-N9) sub types have been identified from influenza viruses of birds, animals and humans. Influenza virus B1 : They are known to infect humans and seals. Influenza virus C:  They are known to infect humans and sometimes pigs.

10. The infection/spreading Mode of transmission of Influenza: Influenza virus infection transmits through air borne route as well as through contaminated hands It spreads from person to person via respiratory secretions during the acts of sneezing and coughing It also transmits by contact with contaminated hands or surfaces.

11. Opportunistic/ seconday infection By continuous replication, epithelial layer of respiratory tract is completely removed. Then many opportunistic normal flora penetrate through damaged epithelium causing opportunistic bacterial infections. Many bacteria like Eg .  Streptococcus ,  staphylococcus  and  Haemophilus   are carried into lungs along with mucus. In lungs these bacteria multiply causing secondary bacterial pneumonia.

12. Treatment 1 Isolation and identification of virus Virus isolation is obtained readily from patients during the first two or three days of illness . Wear mask (Simplest form of Isolation)

13. Treatment 2 Virus cannot be Eliminated/Killed The Drugs usually given designated only for Symptomps

14. Treatment 3 Vaccine Eficient so far Antivirus Delaying Virus Replications