Review Article Oxygen Therapy Part 1 — History, Physiology, and Evaluation Matthew L. Wemple, M.D., Kai E. Swenson, M.D., and Erik R. Swenson, M.D. NEJM Evid Volume 2(5):EVIDra2300005 April 25, 2023
Summary Oxygen is standard therapy for acute cardiopulmonary diseases, and long-term oxygen therapy is common in the outpatient setting. In part I of a two-part review, Wemple and colleagues discuss the physiology of tissue hypoxia, mechanisms of hypoxemia, and its clinical assessment.
Signs and Symptoms of Acute Hypoxia According to System. Wemple ML et al. NEJM Evid2023;2:EVIDra2300005
Causes of Arterial Hypoxemia and Response to Oxygen Therapy. Wemple ML et al. NEJM Evid2023;2:EVIDra2300005