faculty of medicine l (homa IR-test).pptx

faculty of medicine l (homa IR-test).pptx

1. What is HOMA-IR ? Homeostatic Model Assessment of insulin resistance ( HOMA-IR). It gives information on the amount of insulin the pancreas needs to release to control blood sugar. What does HOMA measure ? Homeostatic model assessment (HOMA) is a method for assessing beta-cell function and insulin resistance (IR) from basal (fasting) glucose and insulin or C-peptide concentrations . This test measures how resistant the cells are to insulin.

2. Does HOMA test need fasting ? The measurement of the HOMA-IR index is performed by taking a blood sample. Must have fasted 8-10 hours . What is the HOMA-IR method ? It is calculated using a timely assessment of fasting glucose and insulin concentration. [ fasting glucose ( mmol /L) × fasting insulin ( μmol /L)/22.5] or [ fasting glucose (mg/ dL ) × fasting insulin ( μmol /L)/405].

3. What is a normal HOMA-IR level ? Healthy Range: 1.0 (0.5–1.4 ). Less than 1.0 means you are insulin-sensitive which is optimal. Above 1.9 indicates early insulin resistance. Above 2.9 indicates significant insulin resistance. A high HOMA IR calculator score denotes the presence of insulin resistance , a condition in which the body's cells do not react to insulin as they should .

4. What causes increased HOMA-IR ? Other factors include the following : Body mass index (BMI) greater than or equal to 25 kg/m. Diagnosis of CVD, PCOS, NAFLD, or acanthosis nigricans . A family history of T2D, hypertension, or CVD. Sedentary lifestyle. Non-white ethnicity. Age older than 40 years.