Anti anxiety medications
Prepared and Presented by :
Farah saleem Almaaitah
Submitted to Dr. Faris alsaraireh
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OUTLINE
???Definition of anti anxiety drugs .
???Common medications used as anti anxiety drugs
???Classification of anti anxiety drugs .
???Action , Indications, contraindication and the side effect of
anti anxiety drugs .
???Nursing intervention and health education for possible
side effects
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OBJECTIVES
???At the end of this seminar each student
will be able to:
???Define of antianxiety drugs .
???Identify common medication used as
antianxiety drugs
???Identify classification of antianxiety
drugs .
???Identify action , indications ,
contraindication and the side effect of
antianxiety drugs .
???Nursing intervention and health
education .
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DEFINITION
Antianxiety drugs : also called anxiolytics and
minor tranquilizer . this drugs are used in the
treatment of anxiety disorder , anxiety symptoms.
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ACTION
???Generalized CNS depression .
???Sedative allowing mental
relaxation .
???Skeletal muscle relaxant .
???Anti-convulsant when given I.V .
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INDICATIONS
???Anxiety and tension
???Anxiety prior to surgery , endoscopy , orthopedic
and dental procedure
???Acute withdrawal symptoms of alcoholism
???Status epileptics and seizure disorders
???Tetanus
???Premature labor
???Drug induced convulsions
???Muscle spasm
???Panic disorders
???insomnia
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CONTRAINDICATIONS
/ PRECAUTIONS
⚫Antianxiety drugs are contraindication in
individuals with known hypersensitivity to any of
the drugs within the classification (i.e.
anxiolytics) or group (e.g. benzodiazepines).
⚫They should not be taken in combination with
other CNS depressants and are contraindicated
in pregnancy and lactation , Shock , and coma .
⚫Caution with administering these drug to client
with hepatic dysfunction or sever renal
impairment 7
BENZODIAZEPINES:
✪The major group of antianxiety drugs for
chronic anxiety
✪First drug of this type (Librium) created in
1957.
✪Mild and transient side effects, Safe drug
when take alone
✪Mechanism: Interact with benzodiazepine
receptors and enhance the effect of GABA
(gamma amino butyric acid )
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✪D\C gradually due to withdrawal syndrome .
✪Avoid Juices like grapefruit juice do the inhibitor
cytochrome p 450 enzyme so increase
benzodiazepines life .
✪Cross blood – brain barrier lipid soluble .
✪Side effect : CNS: drowsiness , fatigue , decrease
coordination , mental impairment , slow reflex ,
confusion , depression , headache , memory
impairment , over sedation .
???Paradoxical reaction :agitation , change emotion
children and older adult are more risk .
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Dose (mg) \Day Uses properties Scientific (trade)
name
Tabe:0.25 , 0.5 , 1.0 , 2.0
Oral solu : 0.5 mg / 5 ml
Panic disorder , anxiety
disorder ,antitremor.
Intermediate action &
speed of onset
intermediate
Alprazolam
(Xanax)
Tab & caps : 5 ,
10 ,25
Inj : 100
Acute alcoholic
withdrawal ,antitremor
, anti panic.
Long action for anxiety
disorder relief
syndromes& speed
onset of action
intermediate
Chlordiazepam
(librium)
Tabs : 0.5 , 1 , 2 Panic disorder ,
myloclonic seizures.
Long action for
anticonvulsant &
intermediate onset
of action
Clonazepam
( klonopin)
Tabs : 3.75 , 7.5 , 15 Acute alcohol
withdrawal , partial
seizures ,
anticonvulsant.
Long action for
anxiety & fast onset
of action
Clorazepate
(tranxene)
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1
Dose (mg) \Day Uses properties Scientific
(trade) name
Tabs : 2 , 5 , 10
Oral solu : 5mg\ml ,
5mg\5ml
Inj : 5mg\ml
presurgery
nervousness , skeletal
muscle spasm , status
epileptic's ,alcohol
withdrawal.
Long action for
anxiety disorder short
for relief anxiety
symptoms & very fast
onset of action
Diazepam
(valium)
Tabs : 0.5 , 1.0 , 2.0
Oral solu : 2mg\ml
Inj : 2mg\ml , 4mg\ml
Antitremor ,
antipanic ,
anticonvulsant ,
antiemetic for cancer
pt.
Intermediate action for
anxiety disorder &
slow onset of action.
Lorazepam
(ativan)
Tabs & caps : 10 , 15
, 30
Anxiety associated
with depression
Intermediate acting
for acute alcoholic
withdrawal & slow
onset of action.
Oxazepam
( serax)
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2
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NONBENZODIAZEPINE
(BUSIPIRONE)
✪Act as serotonin agonist (neurotransmitter of
depression ) , for decrease worry irritability .
✪Safe drug
✪Differ of benzodiazepine in : not sedating , not
depress CNS , so it no abuse , no reaction with
alcohol , take 6 weeks to effect , no dependence
or tolerance or withdrawal , not muscle
relaxation
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Dose (mg) Properties Usesclassificatio
n
Scientific
(trade)
name
Tabs : 5 , 10 Effective for
many people less
than
benzodiazepine
Panic
disorder ,
anxiety
disorder , anti
depressant
Miscellaneous Buspirone
(BuSpar )
Nonbenzodiazepine (Busipirone)
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5
Caps : 25 , 50 , 100
Oral susp : 25mg\
5ml
Inj : 25 , 50 , 100
Social anxiety
disorder
Interrupts
physiologic
response of anxiety
related to social
phobia , safe , little
abuse
Propanolol
(
inderal)
Beta Blockers
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HEALTH EDUCATION
Instruct the client not to drive
or operate dangerous
machinery while taking the
medication .
1 *Drowsiness ,
confusion , lethargy
(most common side
effects)
Instruct the client on long-term
therapy not to quit taking the drug
abruptly . Abrupt withdrawal can be
life – threatening . Symptoms include
depression , insomnia , increased
anxiety , abdominal and muscle
cramps , tremors , vomiting , sweating
, convulsions .
2 *Tolerance
physical &
psychological
dependence (dose
not apply to
buspirone )
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Instruct the client not to drink alcohol
or take other medication that depress
the CNS wile taking this medication.
3 *Ability to potentiate the
effects of other CNS
depressants
Assess the clients mood daily .
Take necessary precautions for
potential suicide.
4 *Possibility of
aggravating symptoms
depressed persons
Monitor lying and standing blood
pressure and pulse every shift.
Instruct the client to arise slowly
from a lying or sitting position.
5 *Orthostatic
hypotension
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Withhold drug and notify the physician.
6 *Paradoxical excitement
(client develops symptoms
opposite of the medications
desired effect )
Have the client take frequent sips of
water , suck on ice ships or hard candy ,
or chew sugarless gum .
7 *Dray mouth
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NURSING
CONSIDERATION
❖Monitor vital signs when drug is given IM
or IV , noting hypotension , tachycardia ,
respiratory depression and muscle
weakness
❖Note and report paradoxical reaction like
excitement , muscle spasticity and sleep
disturbances
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❖Warn patient against abrupt withdrawal of
therapy as this may cause vomiting , muscle
cramps and convulsion
❖Advise patient that drug therapy is best
withdraw over several days or weeks unless
urgently needed to stop abruptly
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SUMMARY
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THANK YOU
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Reference
Townsened , M. (2021) . Essentials of psychiatric mental health
nursing. 8
th
ed. Davis puls.
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