female labshsjcgsjgjshgsh 2023 - pdf.pdf

bone

1. Department
practical sessions
Pathology
Lesson8
1)Femalegenitalpathology

2. FG-3Intramuralleiomyoma,uterus

3. FG-3Intramuralleiomyoma,uterus
Grossappearance:
1.Myometriumisoccupiedbywelldefinednon-capsulatedmass
2.Themassispinkishwhite,solid,whorledinappearance

4. FG-4Multipleleiomyomasoftheuterus

5. FG-4Multipleleiomyomasoftheuterus
Grossappearance:
1.Manygreyishwhitenodulesembeddedinthe myometrium
2.Thesenoduleshavebosselatedoutersurface
3.Theinnersurfaceispinkishwhitewhorledin appearance

6. FG-6Leiomyomaofthe cervix

7. FG-6 Leiomyomaofthecervix
Grossappearance:
1.Cervicalcanalanduterinecavityismarkedlydistorted bylarge
tumor
2.Arisesfromcervicalmusclelayer
3.Whorledappearance,solidmass

8. FG-9:Carcinomaofthecervix

9. FG-9:Carcinomaofthecervix
Grossappearance
1.Alargegreyishbrowncauliflowergrowth.
2.Thegrowthinvolvingmainlytheectocervixand infiltratingthe
lowerpartofendocervicalcanal.

10. Slide-85:SimpleEndometrialHyperplasia:
Increasednumbersofendometrialglands
(hyperplasia)
Thestromaisdense,compactandcellular

11. Slide85:SimpleEndometrialHyperplasia
Microscopicfeatures
1.Increasednumberofendometrialglands, somecystically dilated.
2.Thestromaisdensecompactandcellular.

12. FG-8:Carcinomaofbodyoftheuterus

13. FG-8:Carcinomaofbodyoftheuterus
Grossappearance
1.Theendometriumisreplacedbyapolypoidalfriable yellowish
mass.
2.Themassisinfiltratingthemyometriumandfillingthe uterine
cavity.

14. Slide-87:Endometrialadenocarcinoma,
endometrium
Malignantglands

15. Slide-87:Endometrialadenocarcinoma,
endometrium
Microscopicfeatures
1.Endometrialtissueisinfiltratedbyalargenumberof malignant
glands( lined by epithelial showing features of malignancy i.e
pleomorphism, dark nuclei ,disorientation, abnormal mitosis)
2.Intraglandularpapillaryinfoldingsareseen insome glands.

16. FG-10:Hydatidiformmole,trophoblastictissue

17. FG-10:Hydatidiformmole,trophoblastictissue
Grossappearance
1.Delicategreyishbrownmass.
2.Themasshasmultiplethin-walledtranslucentcystic grapelike
structures.

18. Slide-101:Hydatidiformmole,trophoblastic
tissue
Enlargedchorionic
villi
Andproliferationof
trophoblasticcells
Edematouscores
Cytotrophoblast
(mononuclear,
clearcytoplasm,
well-defined cell
membrane)
Syncytiotropho
blast (multiple
nuclei in
eosinophilic
syncytium)

19. Slide-101:Hydatidiformmole,trophoblastic
tissue
Microscopicfeatures
1.Enlargedchorionicvilli,linedbytrophoblasticcells(both cyto-&
syncytiotrophoblasts)showingproliferation.
2.Thecores of thevilliareedematousandavascular.

20. FG-11:Choriocarcinomaoftheuterus,
trophoblastictissue

21. FG-11: Choriocarcinomaoftheuterus,
trophoblastictissue
Grossappearance
1.Theuterusisreplacedbypolypoidnodularhemorrhagic tumorthat
isoccupyingtheendometrialcavity.
2.Thetumorinfiltratingthemyometrium
3.Noformationofchorionicvilli.

22. Slide-88:Choriocarcinomaoftheuterus,
trophoblastictissue
Hemorrhage
Necrosis

23. Slide-88:Choriocarcinomaoftheuterus,
trophoblastictissue
Microscopicfeatures
1.The myometrium is infiltrated by sheets of malignant cells.
2.Thetumorcellsaremalignanttrophoblasts&formedoftwotypesofcells
Syncytiotrophoblast:Irregularlargemultinucleatedcellswith abundant
cytoplasm.
Cytotrophoblast:Smallerpolyhedralwithcentraldarknuclei.
3.Hemorrhageandnecrosisareseen.
4.Nochorionicvilli.

24. FG-14:Serouscystadenomaoftheovary

25. FG-14:Serouscystadenomaoftheovary
Grossappearance
1.Ovalthin-walledovariancyst.
2.Unilocularfilledwithclearfluid.

26. Slide-106:Mucinouscystadenoma,ovary
Cystwallislinedby
Mucinouscolumnar
epithelium

27. Slide-106:Mucinouscystadenoma,ovary
Microscopicfeatures
1.Ovariancystislinedbyasinglelayerof tallcolumnar epithelium
with basal nuclei and apical mucinous cytoplasmicvacuoles.
2.Secretionsarealsoseeninlumens

28. FG-16: Dermoid cyst of the
ovary(Benigncysticteratoma)

29. FG-16:Dermoidcystoftheovary
(Benigncysticteratoma)
Grossappearance
1.Largeovarianmasswiththickwall
2.Partiallysolidpartiallycystic.
3.Cutsurfaceoccupiedbydifferentstructuresof different origins.
4.Tuftofhairispresent.

30. FG-22:Dysgerminomaoftheovary

31. FG-22:Dysgerminomaoftheovary
Grossappearance
1.Largesolidnodulartumorreplacingnormalovary.
2.Theexternalsurfaceshowsconvolutionsanditsbrain-likeappearance.
3.Cutsurfacehomogeneouslygreywhite.

32. FG-24:Kruckenberg’stumor,ovary

33. FG-24:Kruckenberg’stumor,ovary
Grossappearance
1.Bothovariesareenlarged.
2.Externalsurfaceissmooth.
3.Cutsurface:replacementof normalovariantissuebysolidtumor.
4.Theuterusandfallopiantubesappearnormal.

34. Pathology
Department
practicalsessions
Lesson8
2)Breastpathology

35. Slide-89:Fibrocysticchange,Breast
Apocrinemetaplasia
Apocrine
metaplasi
a
Apocrine
metaplasi
a

36. Slide-89:Fibrocysticchange,Breast
Microscopicfeatures:
1.Dilatedductswithcysticformation,thatarelinedbyflatepithelium.
2.Someofthecystsarelinedbytallepitheliumwithabundanteosinophilic
cytoplasm,thischangeistermedasapocrinemetaplasia.
3.Overgrowthofstromalfibroustissueisseenasbandsofhyalinizedfibrous
tissuebetweenthedilatedducts.

37. B-4:Infiltratingductcarcinomaofbreast

38. B-4:Infiltratingductcarcinomaofbreast
Grossappearance:
1.Breastwithnippleretraction.
2.Cutsurfaceshowsinfiltrationofbreastbyirregularill-Defined
greyishbrowntumormass.
3.The tumor is spreading in all directions, surrounding breasttissue,
undertheskin,breastfattissueanddown tothemuscle.

39. Slide-115:Infiltratingductcarcinomaof
breast

40. Slide-115:Infiltratingductcarcinomaofbreast
Microscopicfeatures:
1.Invasivemalignanttumorcomposedofgroups,cordsofpleomorphic,
hyperchromatic,atypicalcellswithabnormalmitoticactivity.
2.Thetumorcellsaresurroundedbydensesclerotic fibrous
stroma(desmoplasia)