Introduction Aberration of normal development and involution (ANDI) Severe form of cyclical changes Take place in the woman's breasts monthly Influences of sex hormones which varies with menstrual cycle Common in reproductive age (25-35 years old) No significant risk of malignancy Except one subtype Atypical ductal hyperplasia
Clinical features Breast pain Lump in the breast Indurated area is found in surgery Biopsy = autopsy finding in normal women fibrosis, adenosis, epitheliosis and cyst formation