TOTAL BODY FLUID IS DIVIDED INTO 2
COMPARTEMENTS:-
1.Intracellular(ICF)
2.Extracellular(ECF)
Total Body Water
INTRACELLULAR COMPARTMENT
Consists of 40% of body weight
EXTRACELLULAR COMPARTMENT
Interstitial fluid- 80% of ECF
Plasma- 20% of ECF
Transcellular fluid
Gastrointestinal
CSF
Peritonial & ocular
Consists of 20% of body water
FLUID LOSS
Plasma water loss
dehydration,anaemia
polycythemia,heart failure
hypoalbuminemia,
abnormal plasma osmolality
Fluid loss in neonates
Insensible water loss ----15 –30ml/kg
Renal water loss -----------60—90ml/kg
Stool water loss-------------10 ml/kg
Growth --------------10—15 ml/kg
Water of oxidation-----------15---18ml/kg
Insensible fluid loss in neonates
Increase in surface area per unit body mass
Decrease in subcutaneous fat tissue
Thin epidermis
Increased permeability of epidermis
causes -----