Friedel craft's alkylation

Friedel craft's alkylation

1. Friedel -craft’s Alkylation Prepared by .-R.M. shelake Asst. Prof. Sojar college of pharmacy khandvi

2. Contents Introduction Reaction Mechanism Limitation

3. Introduction Friedel -Craft’s alkylation involves the formation of new C-C bond between an aromatic ring & an alkyl group. This means that an alkyl group is introduced when benzene reacts with haloalkane in he presence of Lewis acid catalyst i.e. aluminium chloride(AlCl 3)

4. Reaction

5. Mechanism Step-I : Formation of an alkyl cation as an ion pair

6. Step 2 :Attack of the alkyl cation on the aromatic ring

7. Step 3 : Proton transfer regenrates t he aromatic ring

8. Limitation