GAVONIX (Calcium Carbonate, Sodium Bicarbonate, Sodium Alginate)

Gavonix is the combination of two antacids (Calcium Carbonate & Sodium Bicarbonate) & an Alginate (Sodium Alginate).

1. Prepared By
Magferatun Nessa MiLii
Product Manager, PMD
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2. Indication
Heartburn,
Indigestion,
GERD &
Others Hyperacidity related complications.
Many People think that INDIGESTIONand
HEARTBURN are the same but quite often HEARTBURN
is one of the symptoms of INDIGESTION.
2Magferatun Nessa MiLii, PMD

3. Mechanism of Action
isthecombinationoftwoantacids(CalciumCarbonate
&SodiumBicarbonate)&anAlginate(SodiumAlginate).
Gavonixworkintwoways-
1.Neutralizingexcessstomachacidtorelievethepain&
discomfort.
2.Formingprotectivebarrieroverstomachcontentstosoothethe
burningpaininchest.
3Magferatun Nessa MiLii, PMD

4. Mechanism of Action
is a unique combination of –
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Sodium Alginate
•Reacts with acid to form a viscous layer of Alginate, on top of
the stomach content, which exerts anti-reflux action.
Sodium Bicarbonate
•Neutralizes gastric acid & forms Carbon dioxide, which gets trapped
into the viscous gel of Alginate & floats it to the surface of stomach
content.
Calcium Carbonate
•Neutralizes gastric acid & links with Alginate to strengthen protective
raft or barrier on top of the stomach contents, which ensures
stronger & prolong effect.

5. World Gastroenterology Organisation (WGO)&
National Institute for Health and Care Excellence (NICE)
First Line Treatment
for GERD Symptoms
management
If symptoms
persist
Alginate Antacid
(Gavonix) + Proton
Pump Inhibitor(PPI)
Optimal Relief
5Magferatun Nessa MiLii, PMD

6. Dosage And Administration
For Oral Administration
Adults & Children Over 12 Years:
10-20ml after meals and at bedtime, up to four times a day.
Children 6 to 12 Years:
05-10ml after meals and at bedtime, up to four times a day.
Children under 6 years: Not recommended.
Elderly: No dosage modification is required for this age group.
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7. Pregnancy & Lactation
Pregnancy:
This product can be used during
pregnancy.
Lactation:
This product can be used during
breast-feeding.
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8. Key Message
Best Combination for GERD & Indigestion.
Fastest Onset of action within 3 minutes.
Provides long lasting effect up to 4 hours.
Works physically in non-systemic mode of action.
Doesn’t show Acid Rebound effect.
Directly targets the Acid Pocket.
Can be given from 6 years old.
Can also be Co-administered with PPIs.
Safe in Pregnancy & Lactation.
Suitable for Diabetic & Obese Patient.
Free from side-effects like Constipation & Diarrhea.
Doesn’t interfere the nutritional value of food.
Mint Oil exerts Cooling & Soothing Effect just after taken.
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