Glyoxylate cycle PATHWAYS REACTION

A series of metabolic reactions by which many different organism utilise fats for the synthesis of carbohydrate

Another Process Involving Glycolytic Enzymes and Metabolites
Anabolic metabolic pathway occurring in plants, and several
microorganisms , fungi not animals.
Occurs in glyoxysome
The enzymes common to the TCA cycle and the glyoxysomes are isoenzymes, one specific to mitochondria and the other to glyoxysomes.
The glyoxylate cycle allows plants to use acetyl-CoA derived from β-oxidation of fatty acids for carbohydrate synthesis (use fats for the synthesis of carbohydrates).
The glyoxylate cycle is a cyclic pathway that result in conversion of 2 carbon fragment of Acetyl CoA TO 4 carbon compound succinate then succinate is covert to oxaloacetate and then glucose involving the reaction of gluconeogenesis

1. GlyoxYLate cycle Shylesh Murthy I A Follow for More Biological Slides ( LIFE-Sciences ).

2. The Glyoxylate Cycle Another Process Involving Glycolytic Enzymes and Metabolites

3. A series of metabolic reactions by which many different organism utilise fats for the synthesis of carbohydrate

4. Anabolic metabolic pathway occurring in plants, and several microorganisms , fungi not animals. Occurs in glyoxysome The enzymes common to the TCA cycle and the glyoxysomes are isoenzymes , one specific to mitochondria and the other to glyoxysomes . The glyoxylate cycle allows plants to use acetyl- CoA derived from β-oxidation of fatty acids for carbohydrate synthesis (use fats for the synthesis of carbohydrates).

5. The glyoxalate cycle is regarded as an anabolic varient of citric acid cycle . Acetyl coa produced from fatty acid oxidation condenses with oxaloacetate to give citrate , which is then convert to iso citrate . At this stage isocitrate lyase to succinate and glyoxalate . Another molecule of acetyl CoA Is now utilized to combine with glyoolate to form malate synthase and the malate so formed enters citric cycle

6. The glyoxylate cycle is a cyclic pathway that result in conversion of 2 carbon fragment of Acetyl CoA TO 4 carbon compound succinate then succinate is covert to oxaloacetate and then glucose involving the reaction of gluconeogenesis

7. References ; Biochemistry book by U sathyanarayana Chakrapani page no.- 244 INTERNET SOURCES https ://bio.libretexts.org/Bookshelves/Biochemistry/Book%3A_Biochemistry_Free_and_Easy_(Ahern_and_Rajagopal)/06%3A_Metabolism_I/6.06%3A_Glyoxylate_Pathway

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