Hcg and hpl

HCG AND HOP #PLACENTALHORMONES OVERVIEW

1. PLACENTAL HORMONES
HCG AND HPL
@copyright and owner
POKHREL,BHARAT
DOCTOR OF MEDICINE

2. PLACENTA
lFOETAL ORIGIN → CHORION FRONDOSUM
lMATERNAL ORIGIN → DECIDUA BASALIS

3. HORMONES
PROTEIN HORMONES STEROID HORMONES
lhCG
lhPL
lhCT
lHypothalamic and
pituitary like hormones
lOthers like inhibin, relaxin
and beta endorphins
lEsrogens
lProgestin

4. HCG (Human chorionic
gonadotropin)
HPL (Human placental lactogen)
1)It is a hormone produced by the
syncytiotrophoblast, a portion of
the placenta following
implantation
2)The pituitary analog of hCG,
known as luteinizing hormone
3)promotes the maintenance of the
corpus luteum during the
beginning of pregnancy
4) hCG can also be used clinically
to induce ovulation in the ovaries
as well as testosterone production
in the testes.
1)Also called human chorionic
somatomammotropin (HCS), is a
polypeptide placental hormone.
2)Its structure and function is
similar to that of human growth
hormone
3)↓ maternal insulin sensitivity
leading to an increase in maternal
blood glucose levels.
4)↓ maternal glucose utilization,
which helps ensure adequate fetal
nutrition (the mother responds by
increasing beta cells). Chronic
hypoglycemia leads to a rise in
hPL.

5. Picture taken from : http://www.slideshare.net/NadaGYoussef/lecture-4-development-inheritance

6. PRODUCTION OF HCG