Hematology Analyzer Machine - Complete Blood Count
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Jun 09, 2024
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About This Presentation
The CBC machine is a common diagnostic tool used by doctors to measure a patient's red blood cell count, white blood cell count and platelet count. The machine uses a small sample of the patient's blood, which is then placed into special tubes and analyzed. The results of the analysis are th...
Slide Content
Done BY:
Shahd AbdulbasetOsama Khalad
Malak Moheb Yousef Bashara
Shahd AbdulbasetOsama Khalad
Malak Moheb Yousef Bashara
A Complete Blood Count (CBC) is a blood test that measures
various components and features of your blood. It includes red
blood cells, white blood cells, platelets, hemoglobin and
hematocrit.
CBCis commonly performed during routine checkups to detect
disorders such as infections, anemia, immune system disorders, and
blood cancers.
various components and features of your blood. It includes red
blood cells, white blood cells, platelets, hemoglobin and
hematocrit.
CBCis commonly performed during routine checkups to detect
disorders such as infections, anemia, immune system disorders, and
blood cancers.
Specification
Specification Binder
Electrical characteristics
1)A120V,60Hzmono-phaseelectricalsourcewithline
connectionplugNEMA5-15type.
2)Protectionsagainstover-voltageandover-currentline
conditions.
3)CompliancewithapplicableHaitianstandardsand
regulations
4)EquipmentprovidedwithanadequateUninterruptible Power
Supply(UPS)systemwithnotlessthan30minutesof back-up.
√ √ √
√ √ √
√ √ √
√
(Ifrequested)
√
(Preachment)
√
Operationalcharacteristics
5)Benchtopconfiguration,compactmodel,fullyautomated equipment,
autodiluting,forcounting,sizingordifferentiating bloodcells.
6)Sampletype:capillaryorwholeblood.
√ √ √
√ √ √
Electrical characteristics
1)A120V,60Hzmono-phaseelectricalsourcewithline
connectionplugNEMA5-15type.
2)Protectionsagainstover-voltageandover-currentline
conditions.
3)CompliancewithapplicableHaitianstandardsand
regulations
4)EquipmentprovidedwithanadequateUninterruptible Power
Supply(UPS)systemwithnotlessthan30minutesof back-up.
√ √ √
√ √ √
√ √ √
√
(Ifrequested)
√
(Preachment)
√
Operationalcharacteristics
5)Benchtopconfiguration,compactmodel,fullyautomated equipment,
autodiluting,forcounting,sizingordifferentiating bloodcells.
6)Sampletype:capillaryorwholeblood.
√ √ √
√ √ √
Specification Binder
Operationalcharacteristics
7)Ready tousereagents.
8)Throughput:WholeBloodMode≥50samples/hour.
9)Samplevolume≤200μL(wholeblood).
10)Minimumrequirementsformeasuredandcalculated parameters:
WBC,Hb,Ht,RBC,HGB,HCT,MCV,MCH,MCHC,MPV,PLT,RDW,
Monocytes(%,and#),Lymphocytes(%,and#),Granulocytes
Neutrophil,Eosinophil andBasophil(%, and#).
11)Barcodeidentificationforsamplesandreagents.
12)Datastoringcapacitynotlessthan200patientdata samples,with
allparametersandhistograms.
√ √ √
√ √ √
√
(15μL)
√
(17μL)
√
(110μL)
√ √
√
√ √ √
√
(100000DS)
√
(30000DS)
√
(100000DS)
Operationalcharacteristics
7)Ready tousereagents.
8)Throughput:WholeBloodMode≥50samples/hour.
9)Samplevolume≤200μL(wholeblood).
10)Minimumrequirementsformeasuredandcalculated parameters:
WBC,Hb,Ht,RBC,HGB,HCT,MCV,MCH,MCHC,MPV,PLT,RDW,
Monocytes(%,and#),Lymphocytes(%,and#),Granulocytes
Neutrophil,Eosinophil andBasophil(%, and#).
11)Barcodeidentificationforsamplesandreagents.
12)Datastoringcapacitynotlessthan200patientdata samples,with
allparametersandhistograms.
√ √ √
√ √ √
√
(15μL)
√
(17μL)
√
(110μL)
√ √
√
√ √ √
√
(100000DS)
√
(30000DS)
√
(100000DS)
Specification Binder
Operationalcharacteristics
x √ √
√ √ √
√
LIS
Communication
√
√
√
x
√ √ √
Optional
ExternalKey
InternalThermal
Printer
√
Bar Code Scanner
√ √
Bar Code Scanner
Optional
External& Microsoft
OptionalUSB
Printer
√
13)Flexibleanduser-friendlyanalyzersoftwareinFrench languagefor
dataanalysisandreporting.Graphs,histograms and/or
scattergramsavailableformainparameters(atleast WBC,RBC,
PLT).
14)Alertindicators.
15)Built-inorexternaldisplayand workstationor controlpanel;
input/outputdevicesanddataimport/exportcapabilityin standard
formats,fordatamanagementandtransfer.
16)Built-inorexternal printer.
17)Anyotheraccessoryordedicateddevicenecessarytothe proper
functioningandutilizationoftheequipmentincluded.
18)Theequipmentshallpreferablybefunctioningbyuseof reagentsof
mostcommon brands,withoutexclusiveneedof dedicated
reagentsproducedbyasinglesupplier.The compatibleopen
reagentsshallbeavailableinthemarketsof CaribbeanRegion.
Operationalcharacteristics
x √ √
√ √ √
√
LIS
Communication
√
√
√
x
√ √ √
Optional
ExternalKey
InternalThermal
Printer
√
Bar Code Scanner
√ √
Bar Code Scanner
Optional
External& Microsoft
OptionalUSB
Printer
√
13)Flexibleanduser-friendlyanalyzersoftwareinFrench languagefor
dataanalysisandreporting.Graphs,histograms and/or
scattergramsavailableformainparameters(atleast WBC,RBC,
PLT).
14)Alertindicators.
15)Built-inorexternaldisplayand workstationor controlpanel;
input/outputdevicesanddataimport/exportcapabilityin standard
formats,fordatamanagementandtransfer.
16)Built-inorexternal printer.
17)Anyotheraccessoryordedicateddevicenecessarytothe proper
functioningandutilizationoftheequipmentincluded.
18)Theequipmentshallpreferablybefunctioningbyuseof reagentsof
mostcommon brands,withoutexclusiveneedof dedicated
reagentsproducedbyasinglesupplier.The compatibleopen
reagentsshallbeavailableinthemarketsof CaribbeanRegion.
Specification Binder
√ √ √
19)Completewiththenecessarystartupkitofconsumables and
reagentsforinitialtesting,calibrationandtraining activities.
Additionalconsumablesandaccessoriestobeincludedinthebidprice
ReferenceProducerandModel
Hemaray-51 DxH520 ADVIA560
√ √ √
19)Completewiththenecessarystartupkitofconsumables and
reagentsforinitialtesting,calibrationandtraining activities.
Additionalconsumablesandaccessoriestobeincludedinthebidprice
ReferenceProducerandModel
Hemaray-51 DxH520 ADVIA560
It's important to note that the specific cost of a
CBC
machine based on specifications can vary
widely.
CBC
machine based on specifications can vary
widely.
RaytoHemaray51 $5,500 -$5,950
Beckman DxH520 $23,649.00
SIEMENS ADVIA 560 $57,000
Model price
Beckman DxH520 $23,649.00
SIEMENS ADVIA 560 $57,000
Model price
Catalogues Of CBC
Machine
Machine
DxH 520
5-part differential closed tube
hematology analyzer
5-part differential closed tube
hematology analyzer
DxH 520 HEMATOLOGY ANALYZER
Minimum footprint. Maximum productivity.
The new closed tube 5-part differential analyzer—because great things come in small
packages
Spend more time on patient care and less on operational tasks with the powerful, compact
DxH 520 closed tube hematology analyzer, the latest in a legacy of low-volume solutions. With
the DxH 520 closed tube system, laboratories can deliver critical first results accurately, with as
little as 375 µL microtainer fill-volume and an aspiration of only 17 µL.
Experience safety without compromise by using closed tube technology. The DxH 520
analyzer provides optimal security against blood-borne pathogens due to its closed tube
aspiration.
Laboratories can enhance operational flexibility by selecting from an extensive number of
tube types and accommodate cap-pierceable microtainers, such as MAP tubes. The system
streamlines the analysis of puncture samples from infant, child, geriatric, oncology and
critical-care patients. Laboratories can also choose the open tube mode for
even smaller draws and non-cap-pierceable collection tubes.
Provide comprehensive care with less than a drop of blood to test the
most precious patient samples. Technologists can perform 5-part
differential testing with ease, using just a finger-prick amount of blood.
This is ideal for pediatric patients, who routinely provide small sample
volumes at collection. Tests can be added or repeated while using less
blood and without collecting another sample.
› The DxH 520 enables laboratories to:
•Maximize laboratory
productivity
•Reduce overall
operating costs
•Deliver high-quality
clinical results
3
MAXIMIZE LABORATORY PRODUCTIVITY
The DxH 520—designed for high reliability—delivers automated tasks, efficient reagent usage, easy
reagent replacement, and powerful patient and QC data-management tools. All of this means increased
productivity and maximum uptime for laboratories.
Enhance uptime and system maintenance
› Ensure uptime with proven system reliability
Know that results will be delivered precisely when needed. A global, multisite reliability study of the
analyzer’s platform, using more than 36,000 samples, showed an emergency service-call rate of less
than one call per year. With high reliability and a low number of operational tasks, the DxH 520
analyzer is able to achieve an uptime rate greater than 98.5%.
› Discover task automation
Apply the programmable power-up and start-up features with background checks. Users are able
to set the system to activate automatically, before the beginning of a shift, so it is ready to work
when they arrive. Cleaning can also be programmed and automated to minimize daily
maintenance.
› Benefit from quick and
infrequent reagent
replacement
Use only three reagents, requiring
only five minutes or less for
replacement, to keep analysis
running smoothly throughout the
day.
Minimum footprint. Maximum productivity.
The new closed tube 5-part differential analyzer—because great things come in small
packages
Spend more time on patient care and less on operational tasks with the powerful, compact
DxH 520 closed tube hematology analyzer, the latest in a legacy of low-volume solutions. With
the DxH 520 closed tube system, laboratories can deliver critical first results accurately, with as
little as 375 µL microtainer fill-volume and an aspiration of only 17 µL.
Experience safety without compromise by using closed tube technology. The DxH 520
analyzer provides optimal security against blood-borne pathogens due to its closed tube
aspiration.
Laboratories can enhance operational flexibility by selecting from an extensive number of
tube types and accommodate cap-pierceable microtainers, such as MAP tubes. The system
streamlines the analysis of puncture samples from infant, child, geriatric, oncology and
critical-care patients. Laboratories can also choose the open tube mode for
even smaller draws and non-cap-pierceable collection tubes.
Provide comprehensive care with less than a drop of blood to test the
most precious patient samples. Technologists can perform 5-part
differential testing with ease, using just a finger-prick amount of blood.
This is ideal for pediatric patients, who routinely provide small sample
volumes at collection. Tests can be added or repeated while using less
blood and without collecting another sample.
› The DxH 520 enables laboratories to:
•Maximize laboratory
productivity
•Reduce overall
operating costs
•Deliver high-quality
clinical results
3
MAXIMIZE LABORATORY PRODUCTIVITY
The DxH 520—designed for high reliability—delivers automated tasks, efficient reagent usage, easy
reagent replacement, and powerful patient and QC data-management tools. All of this means increased
productivity and maximum uptime for laboratories.
Enhance uptime and system maintenance
› Ensure uptime with proven system reliability
Know that results will be delivered precisely when needed. A global, multisite reliability study of the
analyzer’s platform, using more than 36,000 samples, showed an emergency service-call rate of less
than one call per year. With high reliability and a low number of operational tasks, the DxH 520
analyzer is able to achieve an uptime rate greater than 98.5%.
› Discover task automation
Apply the programmable power-up and start-up features with background checks. Users are able
to set the system to activate automatically, before the beginning of a shift, so it is ready to work
when they arrive. Cleaning can also be programmed and automated to minimize daily
maintenance.
› Benefit from quick and
infrequent reagent
replacement
Use only three reagents, requiring
only five minutes or less for
replacement, to keep analysis
running smoothly throughout the
day.
3
Optimize laboratory performance
›Achieve fast analysis—in 60 seconds or less
Simplify work processes and allow rapid turnaround of specimens with intuitive
and powerful software, helping to minimize patient wait times.
› Create valuable space
Maximize available space with an analyzer that is smaller than a standard microwave
and does not require a separate PC or monitor. The DxH 520 analyzer’s compact
design gives laboratories the flexibility to place instrumentation in optimal locations—
closer to the patient, for example—to create a leaner workflow for greater efficiency.
› Execute any command in three touches or less
Learn how to use the system in less than one hour due to the DxH 520 analyzer’s
intuitive software. Complete any system operation in three steps or less and access all
major functions quickly from any screen.
Improve data and quality control management
› Gain powerful patient data-management tools
•Reduce clerical errors, inefficiencies and risk with a bidirectional interface
•Expand sample storage capacity—up to 30,000 patient samples—for easy delta
checks and file retrieval
•Upload records quickly and easily with a front-side USB connection port
•Ensure patient privacy and security with customizable user login and automated
timeouts with full traceability
› Achieve trusted performance with a robust QC management-tool package
•View Levy-Jennings limits and quality control (QC) results with easy-to-interpret
graphs
•Access online peer-review expertise and support
•Upload new QC lot details with an easy-to-use handheld barcode reader
•Automate daily checks and keep up to 50 data points stored for easy viewing
•Expand QC monitoring with additional techniques, such as the XM, XB and eQC
methods
Patient result screen
Easy backup to restore patient test results,
QC reports and consumable event logs
Easy-to-read QC charts
Preprogrammed daily and
background checks
Optimize laboratory performance
›Achieve fast analysis—in 60 seconds or less
Simplify work processes and allow rapid turnaround of specimens with intuitive
and powerful software, helping to minimize patient wait times.
› Create valuable space
Maximize available space with an analyzer that is smaller than a standard microwave
and does not require a separate PC or monitor. The DxH 520 analyzer’s compact
design gives laboratories the flexibility to place instrumentation in optimal locations—
closer to the patient, for example—to create a leaner workflow for greater efficiency.
› Execute any command in three touches or less
Learn how to use the system in less than one hour due to the DxH 520 analyzer’s
intuitive software. Complete any system operation in three steps or less and access all
major functions quickly from any screen.
Improve data and quality control management
› Gain powerful patient data-management tools
•Reduce clerical errors, inefficiencies and risk with a bidirectional interface
•Expand sample storage capacity—up to 30,000 patient samples—for easy delta
checks and file retrieval
•Upload records quickly and easily with a front-side USB connection port
•Ensure patient privacy and security with customizable user login and automated
timeouts with full traceability
› Achieve trusted performance with a robust QC management-tool package
•View Levy-Jennings limits and quality control (QC) results with easy-to-interpret
graphs
•Access online peer-review expertise and support
•Upload new QC lot details with an easy-to-use handheld barcode reader
•Automate daily checks and keep up to 50 data points stored for easy viewing
•Expand QC monitoring with additional techniques, such as the XM, XB and eQC
methods
Patient result screen
Easy backup to restore patient test results,
QC reports and consumable event logs
Easy-to-read QC charts
Preprogrammed daily and
background checks
REDUCE OVERALL OPERATING COSTS
The efficiently designed DxH 520 can reduce overall operating costs through the use
of
non-toxic reagents and low power consumption for efficient management of the
laboratory’s bottom line.
Preserve valuable resources
›Reducereagentusage
Use50%lessreagentvolumepersample,comparedtootherlow-volume
analyzers.Asingle reagent bottlecansupporthundredsof tests.
›Lowerthecostofdisposal
Utilizecyanide-,azide-andformalydehyde-freereagents,reducingthecostof
disposalaswell ashelpingtomeetenvironmentalandregulatorycompliance
standards.
›Optimizepowerconsumption
Consume less power by using fewer moving parts and energy-efficient
components. A low- energy light source promotes longer life, and a highly
reliable auto-voltage-switching power supply, which regulates voltage
fluctuations.
7
Figure 1a: Optimal measurement zone Figure 1b: Optimal cell pulses identified
DELIVER HIGH-QUALITY RESULTS
The DxH 520 low-volume system provides accuracy through Coulter Principle
technology and Axial Light Loss (ALL) for a 5-part white blood cell (WBC)
differential. Proprietary dynamic gating increases the automated differential
accuracy, delivering more reportable results with less unnecessary flagging.
Hemoglobin is read accurately using the cyanide-free oxyhemoglobin methodology at
545 nm. Counting and sizing is performed in duplicate, also using the Coulter
Principle, for greater precision.
Apply optical analysis—Axial Light Loss (ALL)—and Coulter Principle
innovation to WBC testing
› Combine ALL and Coulter Principle technologies to complete an accurate 5-part
leukocyte differential
Gain accurate cellular information, measured by preserving cells in their native
states. The DxH 520 analyzer does not alter blood cells through staining, shrinkage
or WBC lysis, which can induce fragility in the cells and distort results (Figures 1a
and 1b). The digital information obtained from the WBC blue LED analysis is
processed through the WBC differential algorithm. This information is represented
on a 2D scatter plot, according to Coulter Principle volume, plotted on the Y-axis
and ALL.
1
Users can easily identify cells by color.
8
The efficiently designed DxH 520 can reduce overall operating costs through the use
of
non-toxic reagents and low power consumption for efficient management of the
laboratory’s bottom line.
Preserve valuable resources
›Reducereagentusage
Use50%lessreagentvolumepersample,comparedtootherlow-volume
analyzers.Asingle reagent bottlecansupporthundredsof tests.
›Lowerthecostofdisposal
Utilizecyanide-,azide-andformalydehyde-freereagents,reducingthecostof
disposalaswell ashelpingtomeetenvironmentalandregulatorycompliance
standards.
›Optimizepowerconsumption
Consume less power by using fewer moving parts and energy-efficient
components. A low- energy light source promotes longer life, and a highly
reliable auto-voltage-switching power supply, which regulates voltage
fluctuations.
7
Figure 1a: Optimal measurement zone Figure 1b: Optimal cell pulses identified
DELIVER HIGH-QUALITY RESULTS
The DxH 520 low-volume system provides accuracy through Coulter Principle
technology and Axial Light Loss (ALL) for a 5-part white blood cell (WBC)
differential. Proprietary dynamic gating increases the automated differential
accuracy, delivering more reportable results with less unnecessary flagging.
Hemoglobin is read accurately using the cyanide-free oxyhemoglobin methodology at
545 nm. Counting and sizing is performed in duplicate, also using the Coulter
Principle, for greater precision.
Apply optical analysis—Axial Light Loss (ALL)—and Coulter Principle
innovation to WBC testing
› Combine ALL and Coulter Principle technologies to complete an accurate 5-part
leukocyte differential
Gain accurate cellular information, measured by preserving cells in their native
states. The DxH 520 analyzer does not alter blood cells through staining, shrinkage
or WBC lysis, which can induce fragility in the cells and distort results (Figures 1a
and 1b). The digital information obtained from the WBC blue LED analysis is
processed through the WBC differential algorithm. This information is represented
on a 2D scatter plot, according to Coulter Principle volume, plotted on the Y-axis
and ALL.
1
Users can easily identify cells by color.
8
Figure 2a: Static-gating technology Figure 2b: Dynamic-gating technology
Improve flagging and reduce WBC differential slide reviews—while
maintaining effective clinical sensitivity— with proprietary dynamic-
gating technology
› Improve confidence in the accuracy of the 5-part leukocyte differential with
proprietary dynamic-gating technology compared to a static gate
Take advantage of sophisticated gating technology that improves the
identification of cell populations by adjusting the thresholds between cell-cluster
arrangements. The unique dynamic-gating technology in the DxH 520 analyzer
provides multiple layers of adjustable gates, unlike the static or simple dynamic
gates available in other technologies. With Beckman Coulter’s proprietary
method, the gates move to more proper cutoffs between cell clusters
in a series of steps (Figures 2a and 2b). Improvement is seen in more
challenging cell populations, such as lymphocytes and eosinophils, giving a
more accurate 5-part leukocyte differential than static gating.
› Reduce unnecessary flagging, compared to static- or less-effective
gating techniques
Conduct fewer slide reviews, while maintaining effective clinical sensitivity,
and achieve excellent agreement with manual slide reviews and good
predicative values.
Secure quality CBC results and eliminate guesswork
› Provide fast, accurate CBC analysis using the Coulter Principle and digital
pulse processing
Achieve accurate WBC, red blood cell (RBC), and platelet counting and sizing
with the proprietary Coulter counting method (Figure 3). Digital pulse
processing enables the recognition of data points that fall outside the optimal
counting zone. Removing these unreliable data points enhances count
accuracy (Figures 1a and 1b). Quality results are further improved with dual-
count apertures and a wider linearity range for a more comprehensive patient-
care experience.
Figure 3: Coulter impedance for size and counting
VACUUM
Electrolyte (~50 ohm/cm)
Aperture (~50 ooo ohm/cm)—R=pxl/s
Electrode
Detection area
Couting Impulse
VOLT
Proportional height to the cell volume—U=RxI
Voltage impulse on the electrode terminal
Electric threshold
TIME
Improve flagging and reduce WBC differential slide reviews—while
maintaining effective clinical sensitivity— with proprietary dynamic-
gating technology
› Improve confidence in the accuracy of the 5-part leukocyte differential with
proprietary dynamic-gating technology compared to a static gate
Take advantage of sophisticated gating technology that improves the
identification of cell populations by adjusting the thresholds between cell-cluster
arrangements. The unique dynamic-gating technology in the DxH 520 analyzer
provides multiple layers of adjustable gates, unlike the static or simple dynamic
gates available in other technologies. With Beckman Coulter’s proprietary
method, the gates move to more proper cutoffs between cell clusters
in a series of steps (Figures 2a and 2b). Improvement is seen in more
challenging cell populations, such as lymphocytes and eosinophils, giving a
more accurate 5-part leukocyte differential than static gating.
› Reduce unnecessary flagging, compared to static- or less-effective
gating techniques
Conduct fewer slide reviews, while maintaining effective clinical sensitivity,
and achieve excellent agreement with manual slide reviews and good
predicative values.
Secure quality CBC results and eliminate guesswork
› Provide fast, accurate CBC analysis using the Coulter Principle and digital
pulse processing
Achieve accurate WBC, red blood cell (RBC), and platelet counting and sizing
with the proprietary Coulter counting method (Figure 3). Digital pulse
processing enables the recognition of data points that fall outside the optimal
counting zone. Removing these unreliable data points enhances count
accuracy (Figures 1a and 1b). Quality results are further improved with dual-
count apertures and a wider linearity range for a more comprehensive patient-
care experience.
Figure 3: Coulter impedance for size and counting
VACUUM
Electrolyte (~50 ohm/cm)
Aperture (~50 ooo ohm/cm)—R=pxl/s
Electrode
Detection area
Couting Impulse
VOLT
Proportional height to the cell volume—U=RxI
Voltage impulse on the electrode terminal
Electric threshold
TIME
DANAHER
BUSINESS SYSTEM
CLINICAL
INFORMATION
MANAGEMENT
TOOLS
COMPREHENSIVE,
HIGH-QUALITY CLINICAL
DIAGNOSTIC SOLUTIONS
TOP-TIER SERVICE
AND UPTIME
Beckman Coulter Diagnostic Difference
Partnering Today for a Stronger Tomorrow
Delivering high-quality hematology analyzers such as the DxH 520 system is
part of Beckman Coulter’s vision to advance care for every person. It is one
component of a larger, integrated solution called the Beckman Coulter
Diagnostics Difference, the company’s commitment to partnering with clinical
laboratories to:
›Improve patient care with comprehensive, high-quality clinical diagnostic
solutions, including scalable and reliable systems, advanced workflow
automation and assays designed forquality and accuracy
›Strengthen confidence in clinical and operational decision making
through clinical information-management tools that put people first
›maximizestaffeffectivenessandlaboratoryuptimethroughtop-tier
serviceand instrument uptime
›Drive an achievable and sustainable culture of continuous improvement
through the Danaher Business System (DBS)
Partnering with Beckman Coulter gives laboratories access to this unique,
integrated solution to achieve desired clinical effectiveness and operational
efficiencies.
Discoverthedifference.
1. Beckman Coulter. DxH 520 Instructions for Use v2.
DxH 520 is CE marked. Not available for sale in all countries. Pendi ng cl earance by the Uni ted States Food and
Drug Admi nistration; not yet available for in vi tro di agnosti c use in the U.S.
© 2018 Beckman Coulter, Inc. Al l ri ghts reserved. Beckman Coulter, the styl ized l ogo and the Beckman Coulter
product and servi ce marks menti oned herein are trademarks or regi stered trademarks of Beckman Coulter, Inc.
in the Uni ted States and other countries.
For Beckman Coulter’s worl dwi de offi ce l ocations and phone numbers, pl ease vi sit
www.beckmancoulter.com/contact
BR-66953
Mode of Operation Open and closed tube sampling
Sample Volume
1 7μL of venous or micro-collected whole blood 20 μL of
whole blood for pre-diluted analysis
Throughput 55 closed tube samples per hour, 60 open tube samples per hour
Menu/Test Parameters
WBC, RBC, HGB, HCT, MCV, MCH, MCHC, RDW-SD, RDW-CV, PLT, MPV, LY%, LY#, MO%, MO#, NE%, NE#, EO%, EO#, BA%, BA#
RUO Parameters IMM%, IMM#, LHD, MAF, PCT, PDW
Data Storage
30,000 patient results, including graphics, flags, codes and messages; 1 2 control files, each with a maximum of 1 5 0 runs
User Interface Touch screen; Handheld barcode scanner
Power Requirements 100–240 VAC 50–60 Hz/Single phase with ground
Power Consumption Less than 120W
Operational Ambient
Temperature
18–32°C (64.4–89.6°F)
Humidity 80% relative humidity (non-condensing) at 32°C (89.6°F)
Altitude Up to 3,000 meters (9,843 feet)
External Storage Supports USB 2.0 (five ports)
LIS Supports serial (RS-232) and Ethernet communication
Printer Optional USB printer
Languages Czech, English, French, German, Iberian Portuguese, Italian, Japanese, Romanian, Spanish
Weight and Dimensions
Width Height Depth Weight
270 mm (10.6 in.) 406 mm (16.0 in.) 430 mm (16.9 in.) 1 14Kg (2 51lbs.)
Part Nuber
DxH 520 Hematology Analyzer Specifications
Low-volume
Up to 60 samples/hour
Medium-volume
Up to 100 samples/hour
Medium- to high-volume
Up to 100 samples/hour
High-volume
Up to 200 samples/hour
Ultra-high-volume
Up to 300 Samples/Hour
DxH 500 Series DxH 600 DxH 900 DxH 900-2S DxH 900-3S
Ordering Information Part Number
DxH 520 Hematology Analyzer B40602
DxH 500 Series Diluent (10 L each) B36845
DxH 500 Series Lyse (500 mL each) B36846
Ordering Information Part Number
DxH 500 Series Cleaner (500 mL each) B36868
DxH 500 Series Calibrator (2 x 2.0 mL) B36880
DxH 500 Series Control (6 x 2.3 mL, tri-level sets) B36872
BUSINESS SYSTEM
CLINICAL
INFORMATION
MANAGEMENT
TOOLS
COMPREHENSIVE,
HIGH-QUALITY CLINICAL
DIAGNOSTIC SOLUTIONS
TOP-TIER SERVICE
AND UPTIME
Beckman Coulter Diagnostic Difference
Partnering Today for a Stronger Tomorrow
Delivering high-quality hematology analyzers such as the DxH 520 system is
part of Beckman Coulter’s vision to advance care for every person. It is one
component of a larger, integrated solution called the Beckman Coulter
Diagnostics Difference, the company’s commitment to partnering with clinical
laboratories to:
›Improve patient care with comprehensive, high-quality clinical diagnostic
solutions, including scalable and reliable systems, advanced workflow
automation and assays designed forquality and accuracy
›Strengthen confidence in clinical and operational decision making
through clinical information-management tools that put people first
›maximizestaffeffectivenessandlaboratoryuptimethroughtop-tier
serviceand instrument uptime
›Drive an achievable and sustainable culture of continuous improvement
through the Danaher Business System (DBS)
Partnering with Beckman Coulter gives laboratories access to this unique,
integrated solution to achieve desired clinical effectiveness and operational
efficiencies.
Discoverthedifference.
1. Beckman Coulter. DxH 520 Instructions for Use v2.
DxH 520 is CE marked. Not available for sale in all countries. Pendi ng cl earance by the Uni ted States Food and
Drug Admi nistration; not yet available for in vi tro di agnosti c use in the U.S.
© 2018 Beckman Coulter, Inc. Al l ri ghts reserved. Beckman Coulter, the styl ized l ogo and the Beckman Coulter
product and servi ce marks menti oned herein are trademarks or regi stered trademarks of Beckman Coulter, Inc.
in the Uni ted States and other countries.
For Beckman Coulter’s worl dwi de offi ce l ocations and phone numbers, pl ease vi sit
www.beckmancoulter.com/contact
BR-66953
Mode of Operation Open and closed tube sampling
Sample Volume
1 7μL of venous or micro-collected whole blood 20 μL of
whole blood for pre-diluted analysis
Throughput 55 closed tube samples per hour, 60 open tube samples per hour
Menu/Test Parameters
WBC, RBC, HGB, HCT, MCV, MCH, MCHC, RDW-SD, RDW-CV, PLT, MPV, LY%, LY#, MO%, MO#, NE%, NE#, EO%, EO#, BA%, BA#
RUO Parameters IMM%, IMM#, LHD, MAF, PCT, PDW
Data Storage
30,000 patient results, including graphics, flags, codes and messages; 1 2 control files, each with a maximum of 1 5 0 runs
User Interface Touch screen; Handheld barcode scanner
Power Requirements 100–240 VAC 50–60 Hz/Single phase with ground
Power Consumption Less than 120W
Operational Ambient
Temperature
18–32°C (64.4–89.6°F)
Humidity 80% relative humidity (non-condensing) at 32°C (89.6°F)
Altitude Up to 3,000 meters (9,843 feet)
External Storage Supports USB 2.0 (five ports)
LIS Supports serial (RS-232) and Ethernet communication
Printer Optional USB printer
Languages Czech, English, French, German, Iberian Portuguese, Italian, Japanese, Romanian, Spanish
Weight and Dimensions
Width Height Depth Weight
270 mm (10.6 in.) 406 mm (16.0 in.) 430 mm (16.9 in.) 1 14Kg (2 51lbs.)
Part Nuber
DxH 520 Hematology Analyzer Specifications
Low-volume
Up to 60 samples/hour
Medium-volume
Up to 100 samples/hour
Medium- to high-volume
Up to 100 samples/hour
High-volume
Up to 200 samples/hour
Ultra-high-volume
Up to 300 Samples/Hour
DxH 500 Series DxH 600 DxH 900 DxH 900-2S DxH 900-3S
Ordering Information Part Number
DxH 520 Hematology Analyzer B40602
DxH 500 Series Diluent (10 L each) B36845
DxH 500 Series Lyse (500 mL each) B36846
Ordering Information Part Number
DxH 500 Series Cleaner (500 mL each) B36868
DxH 500 Series Calibrator (2 x 2.0 mL) B36880
DxH 500 Series Control (6 x 2.3 mL, tri-level sets) B36872
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved. Answers for life.
ADVIA 360, ADVIA 560, and
ADVIA 560 AL Systems
Siemens Solutions for Hematology
ADVIA 360, ADVIA 560, and
ADVIA 560 AL Systems
Siemens Solutions for Hematology
The ADVIA Hematology Family
Siemens can now offer a total solution with the
ADVIA
®
360, ADVIA 560, ADVIA 560 AL and ADVIA 2120i HematologySystems.*
The ADVIA Hematology Family
Solutions for all laboratories of all sizes
Safe, reliable, easy to use
Accurate, comparable results
Siemens service and support
Underscores Siemens’ commitment to hematology
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
Siemens can now offer a total solution with the
ADVIA
®
360, ADVIA 560, ADVIA 560 AL and ADVIA 2120i HematologySystems.*
The ADVIA Hematology Family
Solutions for all laboratories of all sizes
Safe, reliable, easy to use
Accurate, comparable results
Siemens service and support
Underscores Siemens’ commitment to hematology
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
ADVIA560SystemSpecifications
Throughput Up to 60 tests/hr
Parameters 26,* including 5-part WBC Differential
Technology Laser light scatter for 5-part Differential Impedance for
CBC
Absorbance for HGB
Samples 110 L sample volume
Closed- and open-tube manual modes
Reagents Three cyanide-free reagents
Quality Control Quality-control database Levey-
Jennings graphs
IT Storage capacity: 100,000 records Easy-to-use
multilingual user interface HL7 connectivity
52 cm
41 cm
49 cm
35 kg
Throughput Up to 60 tests/hr
Parameters 26, including 5-part WBC Differential
Technology Laser light scatter for 5-part Differential Impedance
for CBC
Absorbance for HGB
Samples 110 L sample volume
Closed- and open-tube manual modes
Reagents Three cyanide-free reagents
Quality Control Quality-control database
Levey-Jennings graphs
IT Storage capacity: 100,000 records Easy-to-use
multilingual user interface HL7 connectivity
ADVIA560SystemSpecifications
Throughput Up to 60 tests/hr
Parameters 26,* including 5-part WBC Differential
Technology Laser light scatter for 5-part Differential Impedance for
CBC
Absorbance for HGB
Samples 110 L sample volume
Closed- and open-tube manual modes
Reagents Three cyanide-free reagents
Quality Control Quality-control database Levey-
Jennings graphs
IT Storage capacity: 100,000 records Easy-to-use
multilingual user interface HL7 connectivity
52 cm
41 cm
49 cm
35 kg
Throughput Up to 60 tests/hr
Parameters 26, including 5-part WBC Differential
Technology Laser light scatter for 5-part Differential Impedance
for CBC
Absorbance for HGB
Samples 110 L sample volume
Closed- and open-tube manual modes
Reagents Three cyanide-free reagents
Quality Control Quality-control database
Levey-Jennings graphs
IT Storage capacity: 100,000 records Easy-to-use
multilingual user interface HL7 connectivity
ADVIA 560 AL System Specifications
Throughput Up to 60 tests/hr
Parameters 26, including 5-part WBC Differential
Technology Laser light scatter for 5-part Differential
Impedance for CBC
Absorbance for HGB
Samples 110 L sample volume
Closed- and open-tube manual modes
Autoloader holds 100 samples (10 racks, 10 samples per rack)
Reagents Three cyanide-free reagents
Quality Control Quality-control database
Levey-Jennings graphs
IT Storage capacity: 100,000 records Easy-to-
use multilingual user interface HL7 connectivity
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
ADVIA560andADVIA560ALSystemUser
Interface
Start-up Screen Reagent Status Autoloader Log Result Screen
Throughput Up to 60 tests/hr
Parameters 26, including 5-part WBC Differential
Technology Laser light scatter for 5-part Differential
Impedance for CBC
Absorbance for HGB
Samples 110 L sample volume
Closed- and open-tube manual modes
Autoloader holds 100 samples (10 racks, 10 samples per rack)
Reagents Three cyanide-free reagents
Quality Control Quality-control database
Levey-Jennings graphs
IT Storage capacity: 100,000 records Easy-to-
use multilingual user interface HL7 connectivity
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
ADVIA560andADVIA560ALSystemUser
Interface
Start-up Screen Reagent Status Autoloader Log Result Screen
Quality Control on ADVIA 360 and ADVIA 560
Systems
QC Database and 24 QC files
Target values can be scanned
Levey-Jennings graphs
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
Manual Closed-Vial Sampling
Closed- or open-vial sampling
Suitable for various
cap-pierceable tubes
110 L sample volume
Available on the ADVIA 360,560, and 560 AL Systems
Manual bar-code reader for positive sample ID
Systems
QC Database and 24 QC files
Target values can be scanned
Levey-Jennings graphs
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
Manual Closed-Vial Sampling
Closed- or open-vial sampling
Suitable for various
cap-pierceable tubes
110 L sample volume
Available on the ADVIA 360,560, and 560 AL Systems
Manual bar-code reader for positive sample ID
Tube management
•External Barcode Reader
Code 128; Code 39; Interleaved 2 of 5;
Codabar; EAN-8; EAN-13
•Supported Sample Tube Types
K2- or K3-EDTA 13 x 75-mm sample-tubes
-Sarstedt Monovette
-Becton Dickinson (BD) Vacutainer
-Terumo Venosafe …
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
Autoloader Upgrade on ADVIA 560 System
•External Barcode Reader
Code 128; Code 39; Interleaved 2 of 5;
Codabar; EAN-8; EAN-13
•Supported Sample Tube Types
K2- or K3-EDTA 13 x 75-mm sample-tubes
-Sarstedt Monovette
-Becton Dickinson (BD) Vacutainer
-Terumo Venosafe …
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
Autoloader Upgrade on ADVIA 560 System
Reagents Setup
1.ADVIA 360/560 Dil
•Color Code GREEN
•Dilution of blood sample
•Sheat for optical
measurement
2.ADVIA 560 Lyse 5P
•Color code YELLOW
•Lyses RBCs and PLTs to
determine WBC count, 5-
diff and HGB concentration
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
3.ADVIA 560 Diff-5P
•Color code ORANGE
•Stop the lysing process and
prevent WBC from lysing
1.ADVIA 360/560 Dil
•Color Code GREEN
•Dilution of blood sample
•Sheat for optical
measurement
2.ADVIA 560 Lyse 5P
•Color code YELLOW
•Lyses RBCs and PLTs to
determine WBC count, 5-
diff and HGB concentration
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
3.ADVIA 560 Diff-5P
•Color code ORANGE
•Stop the lysing process and
prevent WBC from lysing
Reagents Setup
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
Reagents Lock System/Hardware (HW)
Key
•Each ADVIA 560 Lyse reagent container
comes with a reagent HW key that
contains 900 measurement credits
•System count down warns operator when
the remaining test is 50
ADVIA 560
Function Diluent Lyse Stopper HypoClean CC Controls Calibration
Product Name
ADVIA 360/560
Dil
ADVIA 560
Lyse
ADVIA 560 5P
Diff
ADVIA 360,560
Hypoclean
ADVIA 560 Control Set
(L-N-H)
ADVIA 360, 560
Calibrator
SMN 11170845 11170846 11170847 11170851 11170854 11170852
Content 20 Ltr
5 Ltr / 900
tests
1 Ltr 100 ml 2 x 3 x 3 mL 2 x 3 mL
Consumption per
measurement
52 mL 5,7 mL 0,7 mL 4mL/jour 110 µL 110 µL
Cycles 380 tests 900 tests 1400 tests 25 days 80 tests 80 tests
Open vial stability 60 days 60 days 60 days 60 days 8 days 7 days
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
Reagents Lock System/Hardware (HW)
Key
•Each ADVIA 560 Lyse reagent container
comes with a reagent HW key that
contains 900 measurement credits
•System count down warns operator when
the remaining test is 50
ADVIA 560
Function Diluent Lyse Stopper HypoClean CC Controls Calibration
Product Name
ADVIA 360/560
Dil
ADVIA 560
Lyse
ADVIA 560 5P
Diff
ADVIA 360,560
Hypoclean
ADVIA 560 Control Set
(L-N-H)
ADVIA 360, 560
Calibrator
SMN 11170845 11170846 11170847 11170851 11170854 11170852
Content 20 Ltr
5 Ltr / 900
tests
1 Ltr 100 ml 2 x 3 x 3 mL 2 x 3 mL
Consumption per
measurement
52 mL 5,7 mL 0,7 mL 4mL/jour 110 µL 110 µL
Cycles 380 tests 900 tests 1400 tests 25 days 80 tests 80 tests
Open vial stability 60 days 60 days 60 days 60 days 8 days 7 days
ADVIA 360 and 560 System Methodology
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
Technologies
Volumetric Impedance Determine the cellular concentration and volume distribution for
WBC, RBC and PLT. The unit is femtoliters (fL).
Photometric Measurement After RBC lysis, HGB concentration is measured based on
absorbance variation against blanc.The unit is g/dL.
Optical Measurement WBC analysis based on a dual-angle measure of light
scattering and diffraction. This determines cell volume
and granularity for each single cell
ADVIA 560 System Result Screen
The Diff cytogram has same orientation and color-coding
as the ADVIA 2120i System
X axis: complexity and granularity
Y axis: cell size
The baso cytogram
X axis: cell complexity
Y axis: cell size
Red cell and platelet histograms
X axis: cell size
Y axis: cell number
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
Technologies
Volumetric Impedance Determine the cellular concentration and volume distribution for
WBC, RBC and PLT. The unit is femtoliters (fL).
Photometric Measurement After RBC lysis, HGB concentration is measured based on
absorbance variation against blanc.The unit is g/dL.
Optical Measurement WBC analysis based on a dual-angle measure of light
scattering and diffraction. This determines cell volume
and granularity for each single cell
ADVIA 560 System Result Screen
The Diff cytogram has same orientation and color-coding
as the ADVIA 2120i System
X axis: complexity and granularity
Y axis: cell size
The baso cytogram
X axis: cell complexity
Y axis: cell size
Red cell and platelet histograms
X axis: cell size
Y axis: cell number
ADVIA 560 vs 2120i System Results (USA)
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
ADVIA560vs2120iSystemResults(USA)
WWBCB
C
WBC HHGB
GB
HGB MCV
MCV
MCV
PLTS NEUTS LYMPHS
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
ADVIA560vs2120iSystemResults(USA)
WWBCB
C
WBC HHGB
GB
HGB MCV
MCV
MCV
PLTS NEUTS LYMPHS
Operator Maintenance ?
Reduced Maintenance
Daily: System Shut Down (automatic)
Weekly: Na*
Monthly: Na*
On demand:
-Shear valve cleaning – 5 min
-Cleaning the Wash head – 5 min
-Measuring chambers – 1 min
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
François Richir / BM / BA LD HH
•Small footprint with onboard cleaning and zero daily maintenance
•Good reliability
•Full support supplied by Siemens
ADVIA560,ADVIA560AL,andADVIA360
Systems
Reduced Maintenance
Daily: System Shut Down (automatic)
Weekly: Na*
Monthly: Na*
On demand:
-Shear valve cleaning – 5 min
-Cleaning the Wash head – 5 min
-Measuring chambers – 1 min
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
François Richir / BM / BA LD HH
•Small footprint with onboard cleaning and zero daily maintenance
•Good reliability
•Full support supplied by Siemens
ADVIA560,ADVIA560AL,andADVIA360
Systems
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