BIOENERGETICS AND ENZYMOLOGY HIGH ENERGY PHOSPHATE COMPOUNDS SUBMITTED BY: S.DHASARADHA BAI 18PBI803
INTRODUCTION All organisms obtain energy from the environment Autotrophic organisms use exergonic process Heterotrophic organisms obtain free energy by coupling their metabolism Atp plays a central role in transfer of free energy from exergonic to endergonic process
ATP STRUCTURE
PHOSPHATE COMPOUNDS Low energy phosphates are exemplified by the ester phosphates High energy phosphates have a value which is greater than that of atp The bonds in the high energy compounds are referred to as high energy bonds The bonds are represented by squiggle discovered by fritz albert lipmann
[ continued ] The term ‘group transfer potential’ is referred as high energy bond Free energy – the energy that is actually available to do work Changes in free energy is gibb’s free energy
High energy phosphates Pyrophosphate - atp Acyl phosphate – 1,3 bis phosphoglycerate Enol phosphates – phospho enol pyruvate Thiol esters – acyl AND ACETYL COMPOUNDS Guanido phosphates – PHOSPHO CREATINE
HIGH ENERGY PHOSPHATES ARE USED IN ENERGY CAPTURE OXIDATIVE PHOSPHORYLATION GLYCOLYSIS CITRIC ACID CYCLE PHOSPHAGENS ARE THE STORAGE FORM OF HIGH ENERGY PHOSPHATES
FUNCTIONS OF ATP SYNTHESIS MUSCLE CONTRACTION ACTIVE TRANSPORT AND SECRETION CHEMICAL REACTIONS