Histology (Skin) - Part 2

1. (sweat glands(eccrine
Sweat gland
Myoepithelial cell
Sweat duct
Secretory cell

2. ECCRINE AND APOCRINE GANDS

3. Skin Glands

4. Structures of skin: hair
follicle
Invagination of epidermis
Hair contains keratin and
melanin
Dermal papilla
Connective tissue
invagination into bulb,
has capillary network
Matrix
Germinative layer
adjacent to dermal
papilla
Also contains
melanocytes
Sebaceous gland
Secretion empties into
hair follicle
Arrector pili muscle
Smooth muscle, inserts
on hair follicle and base
of epidermis
bulb
(dermal papilla)

5. THE HAIR

6. The hair is formed of
Shaft: medulla, cortex and cuticle
The hair follicle is formed of :
Inner root sheath formed of:
Cuticle ,Huxleys layer,Henles layer
Outer root sheath: identical with
Malpighian
Layer of epidermis
Connective tissue sheath

7. Structures of skin: hair
follicle
Dermal papilla
Arrector pili muscle
Sebaceous gland

9. Thick skin vs thin
skin
Thick skin
Palms and soles
Thicker epidermis
Hairless ,more sweat
glands
Thin skin
Everywhere else
Thinner epidermis
Hair, sebaceous
And sweat glands

10. FINGER PRINTS

11. THE PANCREAS

12. The Pancreas

13. Exocrine part
Stroma : thin C.T capsule &trabeculae.
Parencaima : pancreatic acini ,lined with
Pyramidal cells with apical acidophilic
zymogen granules and basal basophilic
striation.
Secrete digestive enzymes via duct system
starting by intercalated ducts.

14. Pancreatic acinus

15. Pancreas
Intercalated ducts
&Centroacinar cells

16. Endocrine Pancreas

17. ISLETS OF LANGERHANS
Non capsolated anastomosing cords of cells
separated by blood sinusoids
Alpha-cells 15-20um, prepheral
Secrete glucacone
20 % stain pink with Gomori
Beta –cells 10-15um, central in position
60-75%, Stain blue with Gomori stain
Secrete insulin

18. Delta cells 2%
Secrete somatostatine which supresses
A,B cells and growth hormone secretion
PP cells 2% secrete pancreatic
polypeptide which is involved in protein
and carbohydrate metabolism.
Ganglion cells
Involved in nervous control of islet
functions.

19. http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Liver/Images/pan20he.jpg

20. Islets- glucagon

21. Islet- insulin

22. Islet-somatostatin

23. Cells of islets of langerhans
Immunohistoch
emical stain
β
δ
α

24. Islet of langerhans

25. Pancreas

26. Pancreas

28. ? ? DO YOU KNOW
Quiz

31. 2. Where are the stem cells of the
epidermis located?
A.
B.
C.
D.
E.

32. 2. What is the name of the layers
labeled (A) &(B) and (C)?
A.
B.
C.
D.
E.

33. The structure at the .3
:pointer
A.is involved in
touch sensation
B.contains
unmyelinated nerve
endings
C. both A and B
D.is involved in
vibratory sensation
E. none of the above

34. Thank youThank you