Skin & appendages 1. Color - pale, flushed, cyanosed, yellow 2. Pigmentation – endocrine, deficiency, infections, metabolic, neurofibramatosus 3. Hypopigmentation - leprosy, leukoderma, albinism, fungal infections of skin 4. Eruptions – macules, papules, pustules, nodules, vesicles, bullae. 5. Neurocutaneous Stigmata ( Phakomatoses ) - Cafe-Au-Lait spots seen in neurofibromatosis, tuberous sclerosis, Sturge weber syndrome. 6. Hemorrhage – purpura, hematoma 7. Types of Skin - dry skin, moist skin, thick skin, thin skin 8. Hair – falling of hair, Patchy hair loss, Loss of outer third of the eyebrow, Absence of axillary, pubic and facial hair, Excessive hair growth in women 9. Nails – Pallor, Koilonychia, Onychia, Discoloration