Sagittally oriented safranin -O–stained sections of an adult human lumbar intervertebral disk (top) and a degenerated intervertebral disk (bottom). Disk matrix stains purple and collagen blue. In the adult disk, the peripheral annulus fibrosus , containing collagen, stains blue (arrowhead). The inner annulus fibrosus and nucleus pulposus , containing GAGs, stains purple. The central portion of the nucleus pulposus , where reticulin , collagen, and elastin fibers are located, stains faintly blue. The degenerated disk has lost purple-staining GAGs from the nucleus pulposus and annulus fibrosus . It conforms to Pfirrmann grade IIII degeneration.
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77 year old woman with h/o hand weakness/numbness/ataxia Prior acdf 14 years ago
Cephalomedullary angle 135-175
48 year old man with right fifth finger pain and numbess
S/P C7T1 ACDF
persistent symptoms of ataxia, neck pain, fine motor hand dysfunction
47 year old woman with 6 month h/o neck stiffness and pain with left UE paresthesias into The elbow forearm and hand especially IF/thumb
Note:the black line directly posterior to the vertebral bodies and relative Thinning of spinal cord, note normal disc height
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Mid-sagittal diameter: width 1:5 ratio leads to necrosis of gray matter Ogino H: Canal diameter, anteroposterior compression ratio and spondylotic myelopathy of the cervical spine. Spine 1983; 8:1-15 Cord compression causes ischemia and direct mechanical trauma
Thanks
Raymond Damadian from Downstate NY published an article in Science 1971 on a technique to differentiate cancer and nomral cells with an MRI. He filed the first USP patent for an MRI on 3/17/72’ he created the first Mri machine
Peter Lauterbur chemist at Universtiy of Illinois created and published the first MRI image of a living mouse in 1973 Physicist Peter Mansfield of the Universtiy of Nottingham developed a mathemantical technique to refine inages 2003 3 Type equation here.
Wilhem Rontgen 1845-1923 1895 xray discovery German physicist Expelled from high school for refusing to reveal a classmate who created a disparaging drawing of a teacher