How to remember drug names easily

How to remember drug names easily with suffix

1. How to remember drug names easily ?

2. Suffix Drug - afil Silden afil Tadal afil Varden afil Avan afil Action/category M/A Vasodilation cGMP - GMP –vasodilation (PDE-v/ Posphodiesterase v inhibitors) Disease Erectile-dysfunction, Pulmonary-arterial-hypertension-PAH

3. Suffix Drug - azepine Carbam azepine Oxcarb azepine Quetia pine Action /category M/A Antiepileptic Na + channel blocker Disease Epilepsy, Schizophrenia, Bipolar disorder, Trigeminal neuralgia

4. Suffix Drug -azole Ketoconazole Miconazole Econazole Clotrimazole Fluconazole Itraconazole Terconazole Butoconazole Tioconazole Posaconazole Voriconazole Action /category M/A Antifungal Blocking fungal CYP450 enzyme ( Cytochromes P450) - Prevent biosynthesis of triglycerides and phospholipid. Disease candidiasis, Fungal infection, Seborrhoeic -dermatitis, Pityriasis-versicolor Imidazole T riazole

5. Suffix Drug - azosin Prazosin Terazosin Doxazosin Action /category M/A Antihypertensive Competitively b locks postsynaptic a lpha 1 adrenoreceptor of vein & artery – Vasodilation Disease Hypertension, Benign prostatic hyperplasia-BPH, Raynaud’s disease,

6. Suffix Drug -bendazole Albendazole Me bendazole Thiabendazole Action/category M/A Anthelminthic Anti-worm Selectively bind to nematode ß-tubulin, inhibiting polymerization, thus preventing the formation of microtubules and so stopping cell division. Block uptake of glucose, leading to depletion of glycogen, and reduced stores of ATP and subsequent parasite immobilization. Disease Helminthiasis, Echinococcosis , Neurocysticercosis, Enterobiasis , Ascariasis, Hookwarm infection, Strongyloidiasis , Giardiasis , Filariasis

7. Suffix Drug - caine Benzocaine Procaine Chlorprocaine Tetracaine Lidocaine Bupivacaine Mepivacaine Ropivacaine Prilocaine Action /category M/A Local anaesthetic Blocks Na ion influx /movements-reduce s depolarisation of ventricles, refractory period, duration of action potential- This block stops nerve conductance and prevents further signals reaching the brain. Disease Hemorrhoids, Perianal pain, Itching, Pupil dilatation, Ventricular-fibrillation, Tachycardia, Surgery, Esters Amides why lidocaine with epinephrine? For loss of feeling (numbness ) The use of local anesthetic agents  WITHOUT Epinephrine  produces a significantly SHORTER duration of action.  Lidocaine with Epinephrine  should provide adequate anesthesia for AT LEAST 3 HOURS.

8. Suffix Drug - capone Entacapone Tolcapone Action /category M/A COMT inhibitors ( catechol-o-methyl transferase ) COMT inhibitor drug inhibits the enzyme COMT. COMT  inhibitors are indicated in combination with levodopa to inhibit it’s peripheral metabolism. Disease Parkinson's disease,

9. Suffix Drug - cillin Penicillin G Penicillin v Amphicillin Amoxicillin Piperacillin Methicillin Action /category M/A Antibiotic Inhibits cross-linking of peptidoglycan production through inactivation trans peptidase- inhibit cell wall synthesis. Disease Meningitis , Anthrax, Pneumonia, Bacterial-Endocarditis, Septicemia, Diphtheria, Syphilis, Gonorrhea, Cellulitis, Lung abscess, Septic arthritis, Gangrene, botulism,

10. Suffix Drug -cycline Tetracycline Oxytetracycline Chlortetracycline Doxycycline Minocycline Action /category M/A Antibiotic Binding to 30S subunits of ribosome- blocks tRNA binding - inhibit protein synthesis Disease Acne, Lyme disease, Gonorrhea, Syphilis, Psittacosis, Q fever, Pleural effusions, Trachoma, Lymphogranuloma venereum , Nongonococcal urethritis. Tetracyclines cannot be  taken with milk and coating drug (gelatin)   because the calcium in the  milk  binds the antibiotic and prevents gut absorption.  Gelatin forms mask and reduce effect. A ntacids  containing Mg,Al , Ca , sodium bicarbonate, calcium supplements, Zn, Fe products, and laxatives containing magnesium interfere with  tetracycline , making it less effective . why tetracycline is given with hydrochloric acid? Answer: So that drug reduces basicity and become slightly acidic .

11. Suffix Drug -dipine Nife dipine Amlo dipine Felodipine Nicardipine Action /category M/A Vasodilator Blocks calcium channel (CCB)- Relaxes peripheral & coronary blood vessels- vasodilation Disease Hypertension, Angina, Stroke, Raynaud’s disease, Atherosclerosis,

12. Suffix Drug -floxacin Cipro floxacin Moxi floxacin Nor floxacin O floxacin Levofloxacin Nalidixic acid Action /category M/A Antibiotic inhibit DNA gyrase- Breakage of double stranded DNA- inhibit DNA reproduction Disease Cystic fibrosis, intra-abdominal infections, Meningitis, Peritonitis, Endocarditis, Anthrax, Otitis media, Otitis externa , Septicaemia , Respiratory tract infection RTI, Urinary tract infection UTI, Biliary tract infection BTI, Cystitis, Gonorrhea, Nosocomial pneumonia, Enteric fever, Typhoid, Bone-joint infection, Q fever, spotted fever, Surgical prophylaxis, Gastroenteritis, Sinusitis, Cat scratch disease, Typhus, Chancroid brucellosis,

13. Suffix Drug - formin Metformin, Action /category M/A Antidiabetic Antihyperglycaemic Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Disease Diabetes mellitus-DM 2 polycystic ovarian syndrome,

14. Suffix Drug - glinide Repaglinide , Nateglinide , Action /category M/A Antidiabetic Meglitinide Lowers blood glucose levels by blocking ATP-dependent potassium channels in pancreatic beta cells, which in turn, stimulates insulin secretion. Disease Diabetes mellitus- DM 2

15. Suffix Drug -gliptin Sita gliptin , Saxa gliptin , Action /category M/A Antidiabeteic dipeptidyl peptidase-4 ( DPP-4 ) inhibitor acts by preventing the degradation of glucagon-like peptide – 1 and hence increases secretion of insulin and decreases secretion of glucagon. Disease Diabetes mellitus- DM 2

16. Suffix Drug - gilline Selegilline , Rasagilline , Action /category M/A MAO B inhibitor (Monoamine Oxidase B) Monoamine oxidase B is an enzyme involved in the metabolism of dopamine. It converts dopamine to its corresponding carboxylic acid via an aldehyde intermediate. MAOB inhibitors bind to and inhibit MAOB, preventing dopamine degradation. Thus inhibit metabolism of dopamine. Disease Parkinson’s disease

17. Suffix Drug -lukast Monte lukast , Zafir lukast , Action /category M/A Leukotriene receptor antagonist Antihistamine works by blocking the action of leukotriene D4 in the lungs resulting in decreased inflammation and relaxation of smooth muscle. Disease Asthma, Allergic rhinitis,

18. Suffix Drug - mab Rituximab, Cituximab , Abciximab , Omalizumab , Trastuzumab , Action /category M/A Antirheumatic Anticancer Monoclonal –antibody Targeting the CD20  (pan-B cell antigen) antigen on normal and malignant B-cells. Then the body's natural immune defenses are recruited to attack and kill the marked B-cells. Disease Non -Hodgkin’s lymphoma, Follicular lymphoma

19. Suffix Drug -metazoline Oxy metazoline Xylo metazoline Action /category M/A Nasal decongestants Binds to and activates alpha-2 adrenergic receptors. Upon nasal or ocular administration, constricts the arterioles in the nose and eye, resulting in decreased nasal and conjunctival congestion. Disease Sinusitis, Hay fever, Common cold, c onjunctival decongestant, Rhinitis, Nasal congestion,

20. Suffix Drug -nidazole Metronidazole, Tinidazole , Ornidazole , Action /category M/A Anti- diarrhoeal Antiprotozoal Converted to reduction products that interact w/DNA to cause destruction of helical DNA structure & strand leading to protein synthesis inhibition & cell death in susceptible organism. Disease Pneumonia, Giardiasis, Peptic ulcer disease-PUD, Peritonitis, H pylori infection, Septicemia, Rosacea, Endometritis , Lung abscess, Empyema, Bone & joint infection, Surgical prophylaxis, Amoebiasis , Bacterial vaginosis , Balantidiasis , Blastocystis hominis infection, Trichomoniasis , Dental infection, Gingivitis, Colitis, Fungating tumours , Leg ulcer & pressure sore, Diverticulitis, Diabetic foot ulcer, Endocarditis, Meningitis & brain abscesses,

21. Suffix Drug - olol Propanolol , Nadolol , Timolol , Atenolol, Bisoprolol , Nebivolol , Betaxolol , Metoprolol , Esmolol , Action /category M/A Beta-blocker inhibits the sympathetic nervous system by blocking the beta-receptors on the nerves. Disease Hypertension-HTN, Migraine, Arrhythmias, Angina pectoris, Myocardial infraction MI, Glaucoma, Ocular hypertension, Congestive heart failure-CHF, Tremor, Hyperthiroidism ,

22. Suffix Drug -penem Imi penem , Mero penem , Doripenem , Ertapenem Action /category M/A Antibiotic Binds to penicillin binding protein (PBP) –Inhibits transpeptidase of peptidoglycan synthesis in bacterial cell wall. Disease Bacterial infection, Septicemia, Pneumonia, UTI, Pyelonephritis, Diabetic foot infection, Meningitis, Cystic fibrosis, Bone-joint infection, Skin infection, Gonorrhea

23. Suffix Drug - platin Cisplatin , Carboplatin, Oxaliplatin , Action /category M/A Anticancer Modify cell cycle by interfering DNA –prominent during S phase-cells are killed at all stages. Disease Lymphomas, Sarcomas, Carcinomas, Lung cancer, Tumors, Bladder cancer,

24. Suffix Drug -prazole Ome prazole, Rabe prazole , Panto prazole, Lanso prazole , Aripiprazole , Action /category M/A PPI Proton pump inhibitor Blocks H+/k+ ATase enzyme of parietal cell – both basal & stimulated acid are inhibited Disease H. Pylori infection, Peptic ulcer (PUD) GI reflux, Zollinger Ellison syndrome, Dyspepsia, Oesophagitis ,

25. Suffix Drug - pril Captopril, Ramipril , Lisinopril , Enalapril , Perindopril, Action /category M/A Angiotensin-converting enzyme (ACE) inhibitor Inhibits the conversion of Angiotensin-I (AT-I) to Angiotensin-II (AT-II) - Reduced aldosterone secretion – increase plasma renin activity- decreased Na and water retention -vasodilation Disease HTN, CHF, MI, Diabetic nephropathy, Heart failure, Stroke,

26. Suffix Drug - quine Chloroquine , Mefloquine , Primaquine , Tafenoquine , Action /category M/A Antimalarial Influences Hb digestion by increasing intravasicular pH in malaria parasite cell- suppressive Disease Malaria, Systemic lupus erythematosus (SLE), Rheumatoid arthritis,

27. Suffix Drug - rubicin Doxorubicin, Danuorubicin , Epirubicin , Idarubicin , Action /category M/A antibiotic Forms stable complex with DNA & interferes with nucleic acid synthesis- cytotoxic in S phase- immunosuppressant & antibacterial effect. Disease Leukaemia, AIDS –related Kaposi’s sarcoma, Carcinoma, Breast cancer, Myeloma, Lymphoma,

28. Suffix Drug - sartan Losartan, Valsartan, Olmesartan , Telmisartan , Azilsartan , Candesartan, Eprosartan , Irbesartan , Action /category M/A Antihypertensive, Angiotensin-ii receptor blocker blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by inhibiting the binding of angiotensin II to the AT  1  receptor. AT  1  receptor blockade results in an increase in plasma renin activity (PRA) followed by increases in plasma angiotensin II concentration. Disease HTN, strokes, Heart attacks, Diabetes nephropathy, Heart failure,

29. Suffix Drug - setron Ondansetron , Palonosetron , Granisetron , Tropisetron , Dolasetron , Action /category M/A antiemetic works by blocking the  action  of serotonin 5-HT 3  receptor, a natural substance that may cause nausea and vomiting. Disease Nausea, Vomiting, nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. 

30. Suffix Drug -statin Atorvastatin, Fluvastatin , Nystatin , Rosuvastatin , Simvastatin, Somatostatin , Pitavastatin , Action /category M/A Antihypercholesterolemia work by competitively blocking the active site of the first and key rate-limiting enzyme in the mevalonate pathway , HMG-CoA reductase . Inhibition of this site prevents substrate access, thereby blocking the conversion of HMG-CoA to mevalonic acid. Disease Primary  hypercholesterolaemia , Mixed dyslipidemia, CVS event prevention,

31. Suffix Drug - tecan Irinotecan , Deruxtecan , Topotecan , Action /category M/A Topoisomerase -I inhibitor inhibits the  action  of topoisomerase-I. prevents religation of the DNA strand by binding to topoisomerase I-DNA complex. The formation of this ternary complex interferes with the moving replication fork, which induces replication arrest and lethal double-stranded breaks in DNA. Disease Carcinoma of colon/rectum,

32. Suffix Drug -thiazide Hydrochlorothiazide, Chlorothiazide , Bendroflumethiazide , Action /category M/A Diuretics  inhibiting reabsorption of sodium (Na + ) and chloride ( Cl − ) ions from the distal convoluted tubules in the kidneys by blocking the  thiazide -sensitive Na + - Cl −   symporter . Disease congestive heart failure, Oedema , heart failure, cirrhosis, chronic kidney failure, corticosteroid medications, nephrotic syndrome. HTN,

33. Suffix Drug - thromycin Azithromycin, Erythromycin, Clarithromycin, Roxithromycin , Action /category M/A Antibiotic, Macrolide binds to the 50S subunit of the bacterial ribosome, thus inhibiting translation of mRNA. Nucleic acid synthesis is not affected. Disease Salmonellosis, Cervicitis, Babesiosis , Otitis media, Tonsillitis, Gonorrhea, Chancroid , Pelvic inflammatory disease- PID, COPD, Endocarditis, UTI, pneumonia, Sinusitis, skin infections, Lyme disease, sexually transmitted infections.

34. Suffix Drug - tidine Cimetidine, Famotidine, Ranitidine, Action /category M/A H2 antagonist Disease

35. Suffix Drug -triptan Sumatriptan , Riza triptan , Almo triptan Zolmitriptan Action /category M/A 5-HT agonist Selective serotonin agonist which acts on the 5-HT 1 receptors & produces cranial vasodilation. Disease Migraine, Headache,

36. Suffix Drug - vir Acyclovir, Oseltamivir , Valganciclovir , Valacyclovir , Tenofovir , Sofosbuvir , Adefovir , Entecavir , Famciclovir , Ganciclovir , Ribavir , Zidovudine , Lamivudine, Action /category M/A Anti-viral inhibits some stage of the virus replication cycle, competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate ( dGTP ). Disease cold sores, Shingles, Chickenpox, genital herpes, Influenza, Hepatitis B, C,

37. Suffix Drug - zolamide Acetazolamide, Brinzolamide , Dorozolamide , Action /category M/A Carbonic anhydrase inhibitor inhibiting the  angiotensin converting enzyme  responsible for the conversion of angiotensin I to angiotensin II. Angiotensin II is a vasoconstrictor causes to increase in blood pressure. Disease Glaucoma, Mountain sickness, Epilepsy, HTN, Idiopathic intracranial, Cardiac edema,

38. Suffix Drug Action /category M/A Disease

39. Thank you

40. Created by_ Md. Jahidul islam Department of pharmacy Jashore university of science & technology