HRT

HRT

1. A 50 year old women presents with history of hot flushes ,irritability and insomnia. She attained menopause 1 year ago. Her BMI is 26 and there are no other risk factors? What do you think her problem is???????????? What is YOUR plan next? Case scenario 1

2. Hormone R eplacement T herapy DR.RUPAL 2

3. Hormone replacement therapy (HRT) is a treatment used to relieve symptoms of the menopause. It replaces female hormone(estrogen)that is at a lower level as you approach the menopause. What is HRT? 3

4. Symptomatic women who suffer from oestrogen deficiency. High risk cases of menopausal complications such as cardiovascular disease, osteoporosis, stroke, Alzheimer’s disease and colonic cancer Premature menopause(spontaneous/post surgery) Gonadal dysgenesis (therapeutic) Women demanding HRT as prophylaxsis . WHO NEEDS HRT? 4

5. ESTROGEN PROGESTERONE TIBOLONE RALOXIFENE BISPHOSPHONATES SOYA ANDROGENS DRUGS USED IN HRT 5

6. ESTROGEN ORAL TRANDERMAL IMPLANTS 6

7. 7

8. 4.VAGINAL 5. INJECTABLE CEE 8

9. ORAL INTRAMUSCULAR INJECTION IMPLANTS IUCD VAGINAL TABLETS AND RINGS SKIN PATCHES PROGESTERONE 9

10. 10

11. TIBOLONE 11

12. SERM 12

13. ANDROGENS 13

14. 14

15. SHORT TERM LO NG TERM HOT FLUSHES OSTEOPOROSIS VASOMOTOR SYMPTOMS CARDIOVASCULAR DISEASE DYSPAREUNIA, LIBIDO ALZHEIMER’S DISEASES URETHRAL SYNDROME USES OF HRT 15

16. RISKS OF HRT 16

17. HOW TO START 17

18. OLDER WOMEN 18

19. MONITORING 19

20. TIME OF CEASING 20

21. THANK YOU 21