Indian pharmacopoeia

Indian pharmacopoeia

1. INTRODUCTION TO INDIAN
PHARMACOPOEIAS
Mr. Ajay Kumar Dubey, Assistant Professor, Institute of Pharmacy
Subject-Inorganic Pharmaceutical Chemistry (BP104T)
[email protected]
Dr. ManjuPandey, Director, Institute of Pharmacy
[email protected]
ShriRamswaroopMemorial University, Barabanki-225003

2. Indian Pharmacopoeia
•UndertheDrugsandCosmeticsAct1940,TheIndian
Pharmacopoeiaisanofficialbookthatcontainsthestandards
fordrugsandotherrelatedsubstancesincludedinthe
pharmacopoeia.
•Thedrugsandotherrelatedsubstancespreparedby
pharmaceuticalmanufacturersmustcomplywiththese
standards.
•ForthepreparationofPharmacopoeiaofIndia,the
pharmacopoeiasofothercountries,likeBritish,Europe,
UnitedStates,USSR,Japan,theNationalFormulary(USA)
andMerckIndexwereconsulted.

3. History of development of Indian Pharmacopoeia
•ThegovernmentofIndiapublishedtheIndianpharmacopoeial
listin1946,asasupplementtotheBritishPharmacopoeia.
•IndianPharmacopoeialListcontainlistofdrugsbothincluded
andnotincludedintheBritishPharmacopoeiaalongwith
standardstosecuretheirusefulness,testsforidentityand
purity.
•TheGovt.ofIndiaconstitutedapermanentIndian
PharmacopoeiaCommitteein1948.
•ThiscommitteewasassignedthetaskofpreparingIndian
Pharmacopoeiaandtokeepitup-to-date.

4. Editions of Indian Pharmacopoeia Indian Pharmacopoeia
•1955-Firstedition,followedbysupplementin1960
•IndianPharmacopoeia1966-Secondedition,followedbysupplementin
1975
•IndianPharmacopoeia1985-Thirdedition,followedbyitsaddendumin
1989and1991
•IndianPharmacopoeia1996-Fourthedition,followedbyitsaddendum
2000,supplement2000forVeterinaryProducts,addendum2002and
addendum2005
•IndianPharmacopoeia2007-Fifthedition,followedbyaddendum2008
•IndianPharmacopoeia2010-Sixedition,followedbyitsaddendum2012
•IndianPharmacopoeia2014withDVD-Seventhedition
•IndianPharmacopoeia2018withDVD-Eighthedition

5. Number of volumes in each edition of IP
•IP 1955, 1965 and 1985 was published in 1
volumes
•IP 1996 was published in 2 volumes
•IP 2007 and 2010 was published in 3 volumes
•IP 2014 was published in 4 volumes
•IP 2018 was published in 4 volumes

6. Contents of the IP 2014 Volume-1
•Introduction General Chapters
•General Notices
•Test Methods
•Apparatus
•Biological Methods
•Chemical Methods
•Physical and Physicochemical Methods
•Pharmaceutical Methods
•Tests on Herbal Products
•Tests on Vaccines
•Tests on Blood and Blood Blood-related Products
•Reference Data
•Reagents and Solutions
•General Tests
•Containers
•Tables

7. Contents of the IP 2014 Volume-2
•General Notices General Monographs on
Dosage Forms Monographs on Drug
substances, Dosage forms and Pharmaceutical
Aids
•Monographs A to M

8. Contents of the IP 2014 Volume-3
•General Notices
•Monographs on Drug substances,
•Dosage forms and Pharmaceutical aids
•Monographs N to Z
•Monographs on Vaccines and Immunoserafor
Human Use
•Monographs on Herbs and Herbal Products
•Monographs on Blood and Blood Bloodrelated
Products
•Monographs on Biotechnology Products

9. Contents of the IP 2014 Volume-4
•Monographs on Veterinary Products o
•Non Non-Biological
•Biological
•Diagnostics Index

10. MONOGRAPH
Title of the Monograph : The main name of the substance (The
International Non-proprietary Name (INN) approved by the World
Health Organization (WHO )).
Subsidiary or abbreviated title or synonym: The common name(s), if
any, of the substance.
Chemical formula and Molecular Weight of the substance : If
necessary, its I.U.P.A.C. chemical name and/or its chemical structure
is also given .
Standards: Prescribes the standards of purity and strength e.g. Sodium
bicarbonate IP contains not less than 99.0 % and not more than
100.5 % of NaHCO3.
Description: A brief description of the physical form of the material,
including colour, texture, whether hygroscopic, odour, if readily
apparent, and any other characteristic

11. MONOGRAPH
Solubility:
Identification:Atleasttwoorthreeidentificationtests,startingwith
physicalandinstrumentaltestsandendingwithgeneralchemical
reactionsisgiven.
Testsofpurity:Thesetestsincludemeltingpoint,boilingpoint,weight
perml,limittestsforchloride,sulfates,iron,heavymetals,leadand
arsenic,specificopticalrotation,sulfatedash,lossondrying,pHof
solution,etc.asmaybeapplicableforthesubstance.
MethodofAssay:Theterm‘Assay’isusedinpharmacopoeiasfor
quantitativedeterminationofprincipalingredientsoftheofficial
substancesandoftheirpreparations.
Storage:Prescribessomeconditionsforthestorageofsomeofficial
substanceswhicharelikelytodeteriorateifnotproperlystored.

12. NATIONAL FORMULARY OF INDIA
•TheNationalFormularyofIndiawouldprovetobethe
authoritativeguidetoprescribing,dispensingand
administeringmedicinesforallhealthcareprofessionals.
TheNationalFormularyofIndiaeditionsareasfollows:-
•NationalFormularyofIndia1960-ThefirsteditionofNFI
•NationalFormularyofIndia1966-TheSecondeditionofNFI
•NationalFormularyofIndia1979–TheThirdeditionofNFI
•NationalFormularyofIndia2011-FourthEditionItcontains
informationaboutdruginteraction,resistance,cumulative
effects,drugdependence,prescriptionwritingetc.

13. CONTENTS OF NATIONAL FORMULARY OF INDIA
•List of Medicines in NFI
•Common Abbreviations
•General Advice to Prescribers
•Alphabetical listing of different classes of drugs with Indications .
•Availability
•Dose .
•Contraindications
•Precautions
•Adverse effects
•Storage
•Appendices
•Index

14. THANK YOU
REFERENCES-
https://en.wikipedia.org/wiki/Indian_Pharmacopoeia
https://www.slideshare.net/
https://www.pharmtech.com/