Dr. SamreenMisbah
MBBS, MPH, MHPE
Assistant Professor Community Medicine Department
Army Medical College, NUMS Rawalpindi
At the end of this 50 minutes session,
Students will be able to;
Discuss disease prevention and control
Discuss disinfection and types of
disinfectant
Learning Objectives
Disease Prevention & Control
•Reducing the
transmission of disease
agent at a low level that
it cease to be a public
health problem
Disease
Control
Disease Prevention &
Control
Basic approach is to
find weakest link in the
chain of transmission
of infection and to
break them
Requires sound
epidemiological
knowledge of the
disease
Disease Prevention & Control
Involves all the measures designed to prevent
or reduceas much as possible the incidence,
prevalence and consequences of disease
Requires
Community participation
Political Support
Inter-sectoralcoordination
Disease Prevention & Control
•1. Controlling Reservoir
•2. Interruption of
Transmission
•3. Protection of
susceptible Host
Control
Measures
1.General Control Measures
of Reservoir
Early
Diagnosis
Notification
Epidemiological
Investigation
Isolation
Treatment
Quarantine
Early Diagnosis
Needed for:
Treatment of patients
Epidemic investigation
Study time, place and person
distribution
Institution of prevention and control
measures
Notification
Notification to local health authorities to
provide medical care to hospitalized patients
and to operate control measures
A valuable source of morbidity data
(incidence and distribution of diseases)
Notification
Health administration are required to notify to
WHO Geneva of communicable diseases under
international health regulations (IHR)
(cholera, yellow fever, plague)
Diseases under surveillance by WHO
Louse borne typhus, relapsing fever, paralytic polio,
viral influenza A, SARS, malaria, smallpox
Notification
Also include Non-communicable diseases
Conditions like cancers, accidents, congenital
defects
Diseases to be notified vary from country to
country
Epidemiological Investigation
Characteris
tics of
Agent
Source or
Reservoir
Vectors
and
vehicles
Susceptible
host
populations
Climatic
condition
Social,
cultural and
behavioural
patterns
Geographi
cal
situation
Isolation
Applied to patients
Purpose is to protect the community by
preventing transfer of infection from the
reservoir to the possible susceptible hosts
Isolation
Separation for the period of
communicability of infected person or
animal to limit or prevent the direct or
indirect transmission of infectious agent
Physical isolation of the cases and carriers,
preferably hospital isolation
Isolation
Distinctive value in diseases (diphtheria,
cholera, plague)
In diseases with large sub-clinical infection
and carrier state (polio, typhoid, hepatitis
A) disease can not be prevented
Unsuccessful in diseases which are highly
infectious before they are diagnosed
(mumps)
Isolation
Chemical isolation by rendering cases non-
infectious through rapid treatment in their
homes (STD, Leprosy, TB)
Because of these limitations and
improvements in epidemiological
technologies isolation is replaced by
Surveillance
Surveillance
Must follow the control measures
It is the continuous scrutiny of all the aspects of
occurrence and spread of disease that are
pertinent to effective control
Surveillance
Once control measures have been instituted,
their effectiveness should be evaluated
If control measures are not successful, failure
reasons should be identifiedand existing
measures modified and evaluation continues
Surveillance
Individual Surveillance of Infected person until they are
no longer risk to others
Local Population Surveillance; Malaria surveillance
National Surveillance Small pox surveillance after its
eradication
International SurveillanceWHO maintains surveillance
of important diseases e.g. polio, malaria, influenza etc.
Treatment
Objectiveis to kill the infectious agent
when it is still in the reservoir before it is
disseminated
Cut short the duration of illness
Reduces the communicability of disease
Prevents development of secondary
cases
Quarantine
Applied to Exposed Well Person
“Limitation of freedom of movement of such
well persons or domestic animals exposed to
communicable disease for a longest usual
incubation periodof the disease, in such a
manner as to prevent effective contact with
those not so exposed”
Quarantine
Absolute quarantine -applied to any means
of transport or container to prevent the
spread of disease reservoir or vector of the
disease
Modified Quarantine: exclusion of sick child
from school
Segregationrefers to the separation of a
healthy person from an infected person
2.Interruption of Transmission
2. Interruption of Transmission
Water can be a medium for transmission of
many infective disease; Water treatment will
eliminate this disease
Food borne disease can be prevented by clean
practices i.e. hand-washing, adequate cooking,
prompt refrigeration, withdrawal of
contaminated food
2. Interruption of Transmission
Vector-borne disease can be controlled by
measures directed towards vector and its
breeding places
Early diagnosis and treatment of patients
and carrier, personal hygiene and proper
handling of secretions and excretion in case
of droplet infection and droplet nuclei
Disinfection
Thermal or chemical Disinfection-destruction of
most recognized pathogens but not bacterial
spores
Disinfectant; “A substance which destroys
harmful microbes (not usually spores) with the
objective of preventing transmission of disease”
It is applicable to only inanimate objects
Hospital disinfectant-registered for use in medical
facility
Alcohol, sodium hypochlorite-bleach, chlorine,
formaldehyde
Sterilization
A process of destroying all viable micro-
organisms including spores
Sterilizer-apparatus used to sterilize
medical devices and instruments by
directly exposing to sterilizing agents
Sterile-state of being free from all living
microorganisms
Antiseptic
A substance which destroys or inhibits the
growth of micro-organisms
Suitable to apply topically to living tissues
Asepsis-prevention of contact with
microorganism
Chlorhexidine, iodine
Sanitizer: agent that reduces the number
of bacterial contaminants to safe levels as
judged by public health requirements
Properties of an ideal disinfectant
Broad spectrum, fast acting
Active in presence of organic matter
Non-toxic to user and environment friendly
Should not corrode instruments
Antimicrobial layer on treated surfaces
Odourless, soluble and stable
Economical and easy to use
Concurrent Disinfection
Measures for disinfection as soon as
possible:
afterdischarge of infectious materials
from the body of an infective person
aftersoiling of articles with infectious
discharges
disinfectionof vomit, urine, faeces,
clothes, hands, dressings, gloves etc.
Terminal Disinfection
Application of measures for disinfection
after the patient has been removed from a
hospital or by death or has ceased to be a
source of infection (It is now not practiced
commonly)
Terminal cleaning is considered adequate
along with airing and sunning of rooms,
furniture and bedding
Pre-current Disinfection
Prophylactic disinfection as:
Disinfection of water by chlorine
Hand washing
Pasteurization of milk
Natural Agents
Sunlight
Direct and continuous exposure to
sunlight is destructive to many organism
bedding, linen, furniture
Airing
Exposure to open air acts by drying or
evaporation of moisture which is lethal
to most bacteria
Physical Agents
Burning or Incineration
Contaminated dressing, rags, swabs etc.
Hot Air
Sterilizing articles such as syringes, swabs,
instruments
Boiling
Rolling boil for 5-10 minutes will kill
bacteria but not spores or viruses
Physical Agents
Autoclaving sterilizers which act at high
temperature (100 degC) and pressure are called
autoclaves.
Most effective sterilizer for absolute sterility of
gloves, syringes, instruments
Not suitable for plastics and sharp instruments
Ionizing radiation
Most effective sterilizer for dressing, needles,
instruments etc.
Very effective but very costly too
Chemical Agents
Alcohols
Available evidence suggests that the most
effective skin antiseptics are alcoholic
solutions of chlorhexidineand iodine
Formaldehyde
Miscellaneous
Lime, ethylene oxide
Faeces & Urine Disinfection
Faeces & Urine should be collected in
impervious vessels
Disinfected by adding equal volume of one of
the disinfectantsand allowed to stand for 1-2
hours
Quicklime can also be used if recommended
one are not available
Faeces & Urine Disinfection
Sputum Disinfection
Best is to receive sputum in gauze or paper
handkerchiefs & destroy by burning
If amount is considerable (as in TB), it may
be disinfected by boiling or autoclaving for
20 minutes at 20 lbs. pressure
Sputum Disinfection
Patient may be asked to spit in a sputum
cup half filled with 5 per cent cresol
When cup is full, it is allowed to stand for
an hour and the contents may be emptied
and disposed off
Room Disinfection
Thorough cleaning, airing & exposure to direct
sunlightwhen possible for several hours
Floor & hard surfaces in the room should be
prohibited for 48 hours
For chemical disinfection, floor and hard
surfaces should be mopped or sprayed with
disinfectant
Room Disinfection
Chlorine preparations such as chlorinated lime
in concentrations that leave 25 ppm or more
of free chlorine
Formaldehyde solutions at a concentration of
1 % or more
Phenol disinfectants such as 2.5 % cresol
Solutions must remain in contact with surface for
at least 4 hours before final washing
Room Disinfection
Fumigationif required, the gas most commonly used
is formaldehyde
It may be generated by boiling commercial formalin
in 2 volumes of water in stainless steel vessel, over
an electric hot plate
There is vigorous boiling and liberation of
formaldehyde gas
Room is kept close for 6-12 hours to allow
disinfection
Medical students have a responsibility to
make every effort to minimize the spread
of infection and to encourage patients
and other health-care workers to actively
engage in practices that minimize the
spread of infection both in the
community, in the hospitals and clinics
What medical students
need to do?