Intergenic segments

1. Intergenic segments Teacher : Oscar Gonzales Davis Student : Mayko V. Tramontini Tapia

2. Also called intergenic regions, Any of the DNA in between gene-coding DNA, including untranslated regions, 5' and 3' flanking regions, INTRONS, non-functional pseudogenes , and non-functional repetitive sequences. This DNA may or may not encode regulatory functions Introns : is any nucelotide sequence within a gene that is removed by RNA splicing which generate the final mature RNA product of a gene

3. The gaps or spaces between the genes that lie on chromosomes termed intergenic regions. By definition, intergenic regions are non-coding, (i.e., they are not transcribed into  codons ) and therefore do not direct the  protein synthesis  via  messenger RNA ( mRNA ). Although not transcribed, intergenic regions have been shown to play a role in the expression of adjacent genes and there is increasing evidence that they contain important control sequences.

4. Recent research suggests, however, that intergenic regions between genes may play critical roles in the process of imprinting, cancers and some  birth defects . Current research projects are attempting to more accurately characterize the intergenic regions near imprinted genes that cause the expression of one parental allele over another

5. Molecular biologist use sophisticated mathematical techniques and modeling enhanced with modern computer technology (e.g. bioinformatic analysis) to identify intergenic   nucleotide  sequences and to investigate their potential role in  cell  regulation. Sophisticated computer algorithms may lead to a more detailed understanding of the role intergenic regions may play in  gene regulation .

6. http://www.bookrags.com/research/intergenic-regions-wog/ http://en.mimi.hu/biology/intergenic.html http://www.biology-online.org/dictionary/Imprinting