Introduction & role of Polymers in CrDDS

Controlled Drug delivery systems

1. POLYMERS
(Introduction, definition, classification,
properties and application)
Dr. Shabnam Ain
Associate Professor & Head
Sanskar College of Pharmacy &
Research, Ghaziabad

2. INTRODUCTION
Polymer is coined from to Greek word “poly” means
many “mer” means parts.
Polymer is defined as very large molecules having
high molecular mass which are formed by joining of
repeating structural unit on large scale.
Monomer : repeating structural unit derived from
some simple and reactive moleculeles are linked to
each other by covalent bond.
Polymerization : process of polymer formation.

4. Protein, cellulose,
resin, rubber,
alginate, gelatin,
albumin.
Nylon , teflon
Polysterylin
Polyethylene,
polypropylene, PLA,
PGA,
Polyhydroxybutyrat
e ,
Polyanhydride,
Polyacrylamide.
Based on Sources

5. Based on polymerization

6. Based on Degradability

7. Based on Nature

8. Based on properties

9. Based on structure

10. Should be inert and compatible with
environment
Should be non toxic
Should be easily administered
Should have good mechanical
strength
Should be biodegradable and
biocompatible
Characteristics of ideal polymer

11. Advantages of polymer
Localised delivery of drug
Sustained delivery of drug
Decrease in dosing frequency
Reduce side effect
Improve patient compliance
Biodegradable and biocompatible
Disadvantages of polymer
Exhibit dose dumping effect
High initial drug release after administration
Low mechanical properties

12. Applications

13. POLYMER APPLICATION
Polyethylene oxide Cosmetic pharmaceuticals
Polyethylene glycol Swelling agent
PVP Tablet granulation
Polyvinyl alcohol Tablet binder and coating
Ethyl cellulose Sustained release system
Carboxy methyl celluloseSuper disintegrant
HPMC Coating and binder

14. 15
Application in Drug delivery system
In modified drug release delivery system
Controlled release formulation
Sustained release formulation
Biomedical applications
Tissue engineering
Bone fixation devices
Vaascular graft
Surgical adhesive
Industrial Application
Agriculture Application
Packaging

15. THANK YOU