Introduction to Biopharmaceutics .pptx

This presentation provides an introduction to biopharmaceutics and Pharmacokinetics , covering key concepts such as drug absorption, distribution, metabolism, and excretion (ADME) with flow chart.

1. UNIT: I Introduction to Biopharmaceutics Biopharmaceutics and Pharmacokinetics - By Mr. Akshanshu Patel Assistant Professor, Dept. of Pharmaceutics Shikhar Institute of Pharmacy

2. Introduction to Biopharmaceutics Biopharmaceutics: It is defined as “study of the factors affecting the rate and amount of drug that reaches the systemic and the use of this information to optimize the therapeutic efficacy of drug”. Biopharmaceutical classification system

3. Pharmacodynamics: Pharmacodynamics is the study of the biochemical and physiological effects of drugs on the body. It focuses on how a drug affects an organism, including its therapeutic and adverse effect. Key concepts: Receptor Binding: Drugs bind to specific receptors to exert their effects. Affinity: The attraction between a drug and its receptor. Efficacy: The ability of a drug to activate its receptor once bound. Potency: The amount of drug needed to produce a desired effect. Dose-Response Relationship : The relationship between drug concentration and its effect on the body Akshanshu Patel

4. Pharmacokinetics: Pharmacokinetics is the study of what the body does to a drug. It involves the processes by which a drug is absorbed, distributed, metabolized, and excreted by the body. Akshanshu Patel

5. Akshanshu Patel Absorption  How a drug enters the body The process of moving from the administration site to the bloodstream. Distribution  How a drug spreads throughout the body The rate at which a drug reaches different sites The extent of a drug's distribution

6. Metabolism How a drug is broken down and altered by the body  The process of biotransformation of a drug by organs or tissues  The production of waste products like carbon dioxide, water, salts, urea, and uric acid  Excretion How a drug is removed from the body as waste  The process of eliminating metabolized drug compounds from the body  The process of transporting intact medication out of the body  Akshanshu Patel