Investigation of thermal-induced decomposition of iodoform

The objective of the article is to investigate the thermal-induced decomposition of iodoform under non-isothermal conditions in a dynamic oxidative atmosphere, aiming to understand the compound's behavior under these conditions and contribute to the knowledge of its thermal stability.

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Universidade Regional do Cariri - URCA
Departamento de Química Biológica
Curso de Graduação em Química
Investigation of thermal-induced decomposition of iodoform
J Therm Anal Calorim - DOI 10.1007/s10973-016-5368-z

Ionut¸ Ledet¸i1 • Marius Murariu2 • Gabriela Vlase3 • Titus Vlase3 • Nicolae Doca3 • Adriana Ledet¸i1 •
Lenut¸a-Maria S¸ uta1 • Tudor Olariu1
Rubem Francisco Silva Bezerra
Crato - CE
2024

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●Historical Significance of Iodoform
●Chemical Properties of Iodoform
●Medical and Industrial Applications
●Research Gaps in Iodoform Studies
Introduction

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The objective of the article is to investigate the thermal-induced
decomposition of iodoform under non-isothermal conditions in a dynamic
oxidative atmosphere, aiming to understand the compound's behavior
under these conditions and contribute to the knowledge of its thermal
stability.
Objective

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●Preparation and purification of iodoform as described in the literature
●Determination of the melting point of iodoform
Bo¨etius PHMK (Veb Analytik Dresden)
●Fourier transform infrared spectroscopy (FT-IR)
Bruker Vertex 70 FT-IR
●Thermogravimetry (TG), derivative thermogravimetric analysis (DTG),
and differential thermal analysis (DTA) measurements
Perkin-Elmer DIAMOND TG/DTA
Materials and methods
Ti = ambient temperature
Tf = 550 ºC
Rate = 10 ºC min-1
ẞ = 5, 7, 10, 12 and 15 C min⁻¹


TG/DTG/DTA

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Synthesis of iodoform
Iodine 3g
Acetone 3mL
Agitation
NaOH 5%
Disproportion
Filtration
Dried for 2h at 35 ºC


Product
Hot ethanol
Cooling at room temperature
Filtration
Dried for 24h at 35 °C

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Iodoform mechanism

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ATR-FTIR

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TG/DTG/DTA

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Plottings of the selected isoconversional methods used in the kinetic study

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Plottings of the selected isoconversional methods used in the kinetic study

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The Ea values obtained by isoconversional methods for IDF

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Ea versus a variation by the employment of isoconversional methods

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In all cases, good linear correlations were
obtained, with determination coefficients higher
than 0.984. The estimation of Ea values was
realized from the slopes of those lines, for 0.05 B
a B 0.95, with a variation step for a of 0.05.

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Conclusions
All the results obtained by the employment of isoconversional methods
are in good agreement; the mean apparent activation energy was around 330
kJ mol-1 by all three methods. However, since variation larger than 10 % of Ea
versus a was noticed, the NPK method was employed, and the separation of
physical versus chemical transformations of the sample was possible. NPK
method suggested that the degradation of iodoform occurs in two parallel
processes, the main step being a chemical degradation (n = 1/3), while the
parallel process is a physical–chemical one (n = 3/5; m = 1/3).

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Any question?

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