Progressive disorder in which the cornea
assumes a conical shape secondary to corneal
thinning and protrusion
Onset is around puberty- progresses untill 3
rd
or 4
th
decades of life
Both eyes affected usually
Role of hereditary transmission is not clear.
PRESENTATION
Presents usually during puberty.
Impairment of vision due to progressive
myopia and irregular astigmatism.
Asymmetrical nature.
Approximately 50% of normal fellow eyes will
progress to keratoconus within16 years.
DIAGNOSIS
Central or paracentral stromal thinning,
apical protrusion and irregular astigmatism
SIGNS:
Direct ophthalmoscopy shows ‘oil droplet
sign’.
Retinoscopy shows irregular’ scissor’ reflex’
Slit lamp microscopy showsfine, vertical,
deep stromal striae called vogts striae .
Epithelial iron deposits may surround the
base of cone –’fleischer ring’.
Marked irregular myopic astigmatism with
steep keratometry reading.
Bulging of the lower lid in down gaze-
‘munson sign’.
Corneal topography – sensitive method of
detecting early keratoconus.
ACUTE HYDOPS
Caused by rupture of descemets membrane
that allows influx of aqueous into the conea.
Causes sudden drop in visual acuity with
discomfort and watering.
Usually the break heals within 6-10 weeks and
edema clears but scarring results
Treatment is keratoplasty after edema
resolves.
ASSOCIATIONS
SYSTEMIC DISORDERS LIKE Down, Turner,
Ehler-Danlos and Marfan syndromes, atopy,
oesteogenesis imperfecta, MVP, mental
retardation.
OCULAR DISORDERS like vernal kerato
conjunctivitis, blue sclera, aniridia, ectopia
lentis, RP
TREATMENT
Spectacles in early stages.
Rigid contact lenses for higher degrees of
irregular astigmatism..Piggy back lenses.
Keratoplasty : both lamellar and penetrating
keratoplasty especially in cases of severe
corneal scarring.