Levera (Levetiracetam Tablets)

Levera (Levetiracetam Tablets) is used for adjunctive therapy in the treatment of partial onset seizures in patients 12 years of age and older with epilepsy.

1. Levetiracetam Tablets
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Levera (Levetiracetam Tablets) is used for
adjunctive therapy in the treatment of partial
onset seizures in patients 12 years of age
and older with epilepsy.

2. Levera Tablets
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Levera Tablets are manufactured by
Intas Pharmaceuticals Ltd., India
(Website: www.intaspharma.com)

3. Levetiracetam Tablets – Brand Names
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Levetiracetam tablets are available as
Keppra, Levera, Levera-XR, Levepsy,
Levefree, Levexx, Levilex, Levipil,
Levroxa , Levtam, Torleva, Torleva-
XR and Vitisun.

4. Active Ingredient
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The active ingredient contained in Levera
tablets is Levetiracetam. Each Levera tablet
contains 250 mg, 500 mg, 750 mg or 1000 mg
of Levetiracetam.

5. Chemical Structure
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The structure of Levetiracetam is given below:

6. Uses of Levera Tablets
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Levera (Levetiracetam Tablets) is used as
adjunctive therapy in the treatment of partial
onset seizures in adults and children 1
month of age and older with epilepsy, in the
treatment of myoclonic seizures in adults
and adolescents 12 years of age and older
with juvenile myoclonic epilepsy and as
adjunctive therapy in the treatment of
primary generalized tonic-clonic seizures in
adults and children 6 years of age and older
with idiopathic generalized epilepsy.

7. Levera Dosage

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➢Dosing for Partial Onset Seizures (Adults 16
Years and Older).Start treatment with a daily
dose of 1000 mg/day, given as twice-daily
dosing (500 mg twice daily). Additional dosing
increments may be given (1000 mg/day
additional every 2 weeks) to a maximum
recommended daily dose of 3000 mg.
Levera (Levetiracetam Tablets) is administered
orally with or without food.
The dosage of Levera tablets (Levetiracetam) is
given below:

8. Levetiracetam Tablets Dosage

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➢Dosing for Myoclonic Seizures in Patients 12 Years of
Age and Older with Juvenile Myoclonic Epilepsy:
Treatment has to be started with a dose of 1000
mg/day, given as twice-daily dosing (500 mg twice
daily). Increase the dosage by 1000 mg/day every 2
weeks to the recommended daily dose of 3000 mg.
➢Dosing for Primary Generalized Tonic-Clonic
Seizures in Adults 16 Years and Older: Treatment has
to be started with a dose of 1000 mg/day, given as
twice-daily dosing (500 mg twice daily). The dosage
may be increased by 1000 mg/day every 2 weeks to
the recommended daily dose of 3000 mg.
The dosage of Levera (Levetiracetam Tablets) is
given below:

9. Warnings

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Before taking Levetiracetam tablets, inform
your doctor or pharmacist if you are allergic to
it; or if you have any other allergies.
Antiepileptic drugs (AEDs), including
Levera (Levetiracetam Tablets), increase the
risk of suicidal thoughts or behavior in
patients undergoing therapy with these
medicines for any indication.
Patients treated with any AED for any
indication must be monitored for the
emergence or worsening of depression,
suicidal thoughts or behavior, and/or any
unusual changes in mood or behavior.

10. Warnings

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This medicine may make you dizzy or drowsy,
especially during the first month of treatment. Do not
drive, use machinery, ride a bicycle, or do any
activity that requires alertness until you are sure you
can perform such activities safely.
Limit alcoholic beverages.
Children may be more sensitive to the side effects of
this medicine, especially mental/mood changes
(such as irritability, aggression, agitation, anger,
anxiety, depression, thoughts of suicide).
Children younger than 4 years may be at greater risk
for increased blood pressure while using this
medication.
Withdrawal Seizures: Levera (Levetiracetam
Tablets) must be gradually withdrawn

11. Storage Instructions

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Levera (Levetiracetam Tablets) have to
be stored at controlled room temperature
i.e. 25°C . Protect from light.
Keep this as well as all other medicines
away from children and pets.

12. Levera Tablets
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Contraindications
Levera is contraindicated in patients
with a hypersensitivity to
Levetiracetam or any other
component of this medication.

13. Levera Side Effects
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➢Most common Levera side effects of
with an incidence rate of 5% or more and
greater than placebo include
somnolence, infection, and irritability.
➢Get medical help immediately in case
you notice any symptoms of a serious
allergic reaction to Levera (Levetiracetam
Tablets), such as: rash, itching/swelling
(especially of the face, tongue or throat),
severe dizziness, trouble breathing.

14. Levetiracetam Overdose
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Somnolence, agitation, aggression,
depressed level of consciousness,
respiratory depression and coma were the
symptoms observed in cases of
Levetiracetam overdoses.

15. Levetiracetam Overdose
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There is no specific antidote for an overdose with
Levera (Levetiracetam Tablets).
If necessary, elimination of the unabsorbed drug
should be attempted by emesis or gastric lavage
and the normal precautions should be observed
to maintain the airways.
General supportive care of the patient is
indicated, including monitoring of vital signs and
observation of the patient's clinical status.
Standard haemodialysis procedures result in
significant clearance of Levetiracetam
(approximately 50% in 4 hours) and must be
considered in cases of overdose.

16. Levetiracetam During Pregnancy
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Levetiracetam (Levera Tablets) has been
classified by the US FDA as Pregnancy
Category C .
During animal studies with Levetiracetam, it
was observed that developmental toxicity
occurs at doses similar to or greater than
human therapeutic doses.
During pregnancy, this medication must be
used only when clearly needed. It can harm
an unborn baby.

17. Levera Tablets
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Levera Tablets click here
© Clearsky Pharmacy
Levera (Levetiracetam Tablets) by Intas
Pharmaceuticals Limited, India.